| P50 | author | Arnauld Sergé | Q58808086 |
| | Magali Irla | Q38304798 |
| P2093 | author name string | Pierre Ferrier | |
| | Noëlla Lopes | |
| P2860 | cites work | Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens | Q21131226 |
| | An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains | Q24313206 |
| | Essential role for ZAP-70 in both positive and negative selection of thymocytes | Q24321424 |
| | Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus | Q24597291 |
| | Transcriptional regulation by AIRE: molecular mechanisms of central tolerance | Q24648384 |
| | Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla | Q27324446 |
| | Positional cloning of the APECED gene | Q28116470 |
| | Projection of an immunological self shadow within the thymus by the aire protein | Q28207164 |
| | Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system | Q28255466 |
| | Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance | Q28585306 |
| | Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) | Q28590962 |
| | Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance | Q28593303 |
| | Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see) | Q29391777 |
| | Regulatory T cells: mechanisms of differentiation and function | Q29620731 |
| | CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus | Q33722636 |
| | B cells participate in thymic negative selection of murine auto-reactive CD4+ T cells | Q33728132 |
| | CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease | Q33980867 |
| | MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity | Q34096499 |
| | Adult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic epithelial lineages | Q34106631 |
| | NF-κB-inducing kinase in thymic stroma establishes central tolerance by orchestrating cross-talk with not only thymocytes but also dendritic cells. | Q54319219 |
| | Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. | Q54380933 |
| | Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. | Q55035366 |
| | Medullary thymic epithelial stem cells maintain a functional thymus to ensure lifelong central T cell tolerance. | Q55058749 |
| | Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance | Q56701390 |
| | T cell tolerance by clonal elimination in the thymus | Q56922465 |
| | Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population | Q59056890 |
| | A Role for Intrathymic B Cells in the Generation of Natural Regulatory T Cells | Q61631808 |
| | Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development | Q62024090 |
| | Unbiased analysis, enrichment and purification of thymic stromal cells | Q62078505 |
| | Thymic CCL2 influences induction of T-cell tolerance | Q63190400 |
| | Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity | Q63190413 |
| | Epithelial heterogeneity in the murine thymus: fucose-specific lectins bind medullary epithelial cells | Q69834637 |
| | Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment | Q70212975 |
| | CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium | Q71169434 |
| | Monoclonal antibodies to stromal cell types of the mouse thymus | Q71390646 |
| | Maturation of medullary thymic epithelium requires thymocytes expressing fully assembled CD3-TCR complexes | Q72403451 |
| | CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen | Q73520530 |
| | Functional comparison of thymic B cells and dendritic cells in vivo | Q73642967 |
| | Thymic vasculature: organizer of the medullary epithelial compartment? | Q73959276 |
| | In Vivo Treatment of Class II MHC-Deficient Mice with Anti-TCR Antibody Restores the Generation of Circulating CD4 T Cells and Optimal Architecture of Thymic Medulla | Q79074350 |
| | Lymphotoxin beta receptor is required for the migration and selection of autoreactive T cells in thymic medulla | Q80139452 |
| | Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected | Q81464228 |
| | Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance | Q83863991 |
| | Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner | Q84394189 |
| | Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance | Q34112986 |
| | Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus | Q34247810 |
| | Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation | Q34533105 |
| | Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells | Q34576335 |
| | Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development | Q34577749 |
| | Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia | Q34590391 |
| | The impact of circulating dendritic cells on the development and differentiation of thymocytes | Q34601204 |
| | Dendritic cells in the thymus contribute to T-regulatory cell induction | Q34601754 |
| | Negative selection--clearing out the bad apples from the T-cell repertoire | Q35136005 |
| | For3D: Full organ reconstruction in 3D, an automatized tool for deciphering the complexity of lymphoid organs | Q35625520 |
| | Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance | Q35861549 |
| | Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase | Q35925641 |
| | Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium | Q36011240 |
| | Heterogeneity of thymic dendritic cells | Q36157476 |
| | Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire | Q36229072 |
| | Thymic emigration revisited | Q36229138 |
| | Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment | Q36322501 |
| | Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development | Q36369382 |
| | Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. | Q36371648 |
| | Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation | Q36399298 |
| | Journey through the thymus: stromal guides for T-cell development and selection | Q36402237 |
| | Modifier loci condition autoimmunity provoked by Aire deficiency | Q36403033 |
| | Murine thymic selection quantified using a unique method to capture deleted T cells | Q36712531 |
| | Zoned out: functional mapping of stromal signaling microenvironments in the thymus | Q36732547 |
| | The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development | Q36750060 |
| | Aire-dependent thymic development of tumor-associated regulatory T cells | Q36754190 |
| | Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells | Q36932226 |
| | Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla | Q36946557 |
| | Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus | Q37234298 |
| | Autoreactive thymic B cells are efficient antigen-presenting cells of cognate self-antigens for T cell negative selection | Q37240479 |
| | Antigen-presentation properties of plasmacytoid dendritic cells | Q37272231 |
| | Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity | Q37273185 |
| | Lineage tracing and cell ablation identify a post-Aire-expressing thymic epithelial cell population | Q37288027 |
| | Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells | Q37303952 |
| | The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells | Q37382924 |
| | CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens | Q37386006 |
| | The impact of negative selection on thymocyte migration in the medulla. | Q37476326 |
| | Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways | Q37501186 |
| | An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells | Q37627734 |
| | Antigen presentation in the thymus for positive selection and central tolerance induction | Q37638193 |
| | Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors | Q37650757 |
| | Control of central self-tolerance induction by autoreactive CD4+ thymocytes | Q37651855 |
| | How thymic antigen presenting cells sample the body's self-antigens | Q37787422 |
| | The mechanism of tissue-restricted antigen gene expression by AIRE. | Q38086140 |
| | Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases | Q38132390 |
| | Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus | Q38466522 |
| | Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla | Q39207497 |
| | Intercellular MHC transfer between thymic epithelial and dendritic cells | Q39992060 |
| | Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation | Q40463872 |
| | Crosstalk in the mouse thymus | Q40668183 |
| | Thymus medulla consisting of epithelial islets each derived from a single progenitor | Q40763624 |
| | Medullary thymic epithelial cells induce tolerance to intracellular proteins. | Q41236038 |
| | Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice | Q41854796 |
| | RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla | Q41868543 |
| | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens | Q42147296 |
| | The phenotypic heterogeneity of mouse thymic stromal cells | Q42481348 |
| | The thymic medulla: a unique microenvironment for intercellular self-antigen transfer | Q42572856 |
| | Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand | Q42767299 |
| | Growth of epithelial cells in the thymic medulla is under the control of mature T cells | Q42769057 |
| | CCR7 signals are essential for cortex-medulla migration of developing thymocytes. | Q42971212 |
| | Expression of the alpha beta T-cell receptor is necessary for the generation of the thymic medulla | Q43088727 |
| | CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus. | Q43434964 |
| | Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen | Q43554100 |
| | Analysis of APC types involved in CD4 tolerance and regulatory T cell generation using reaggregated thymic organ cultures | Q43679325 |
| | Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input | Q43809296 |
| | A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla | Q44996730 |
| | Murine thymic plasmacytoid dendritic cells | Q46551221 |
| | Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors. | Q46978934 |
| | Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction. | Q50582693 |
| | Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus. | Q50640787 |
| | Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo. | Q50883531 |
| | Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency. | Q51286881 |
| | The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. | Q51949099 |
| | Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells. | Q51972426 |
| | NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. | Q52093900 |
| | Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance. | Q53253030 |
| | The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. | Q53453365 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 365 | |
| P577 | publication date | 2015-07-20 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction | |
| P478 | volume | 6 | |