Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus

scientific article published on 09 March 2009

Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20082232
P932PMC publication ID2699131
P698PubMed publication ID19273629
P5875ResearchGate publication ID24188942

P2093author name stringIrving Goldschneider
JiChu Li
Deborah Foss
JooHung Park
P2860cites workBidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activationQ28213281
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymusQ28268867
Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1Q28509825
Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endotheliumQ28572680
Blood monocytes consist of two principal subsets with distinct migratory propertiesQ29614286
Use of interleukin 7 receptor-alpha knockout donor cells demonstrates the lymphoid independence of dendritic cellsQ34312818
Designer dendritic cells for tolerance induction: guided not misguided missilesQ34319943
Intrasplenic steady-state dendritic cell precursors that are distinct from monocytesQ34522666
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.Q34566731
Steady-state and inflammatory dendritic-cell developmentQ34591334
Dendritic cells in the thymus contribute to T-regulatory cell inductionQ34601754
Thymic dendritic cells traffic to thymi of allogeneic recipients and prolong graft survivalQ34789662
A central role for peripheral dendritic cells in the induction of acquired thymic toleranceQ35053394
Plasmacytoid dendritic cells in immunityQ35953140
Heterogeneity of thymic dendritic cellsQ36157476
Development of murine plasmacytoid dendritic cell subsets.Q36262296
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Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivoQ36365201
Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulusQ36371026
The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult miceQ36376184
Dendritic cell development in culture from thymic precursor cells in the absence of granulocyte/macrophage colony-stimulating factorQ36377402
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levelsQ36402949
Generation, migration and function of circulating dendritic cellsQ36507785
In vitro-generated antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells control the severity of herpes simplex virus-induced ocular immunoinflammatory lesionsQ36747712
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant miceQ36780661
Regulatory T cells and infection: a dangerous necessityQ36975739
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cellsQ38336314
Clonal deletion of thymocytes by circulating dendritic cells homing to the thymusQ38466522
Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated miceQ41854796
A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodesQ42039464
Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cellsQ42114183
Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligandQ42767299
Tolerance to cyclosporin A-induced autologous graft-versus-host disease is mediated by a CD4+CD25+ subset of recent thymic emigrantsQ43628927
Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration.Q43855733
Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potentialQ44045898
Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against LeishmaniaQ44920559
Targeted lymphoid homing of dendritic cells is required for prolongation of allograft survivalQ46108818
Murine thymic plasmacytoid dendritic cellsQ46551221
Regulation of thymus size by competition for stromal niches among early T cell progenitorsQ47413321
CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells.Q51990381
Characterization of distinct conventional and plasmacytoid dendritic cell-committed precursors in murine bone marrow.Q52088536
Two developmentally distinct populations of dendritic cells inhabit the adult mouse thymus: demonstration by differential importation of hematogenous precursors under steady state conditions.Q52107789
Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage.Q52114388
Distinct functional capacities of mouse thymic and splenic dendritic cell populations.Q53455335
Origin of dendritic cells in peripheral lymphoid organs of mice.Q53558035
In situ replication of immediate dendritic cell (DC) precursors contributes to conventional DC homeostasis in lymphoid tissue.Q53619790
Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8- and CD8+ splenic dendritic cells.Q54741751
"Alternatively activated" dendritic cells preferentially secrete IL-10, expand Foxp3+CD4+ T cells, and induce long-term organ allograft survival in combination with CTLA4-IgQ56901846
Role for thymic and splenic regulatory CD4+ T cells induced by donor dendritic cells in allograft tolerance by LF15-0195 treatmentQ56904437
Thymic recognition of class II major histocompatibility complex allopeptides induces donor-specific unresponsiveness to renal allograftsQ57704413
Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivoQ63917052
Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. A study in parabiotic miceQ67880403
Recruitment of semiallogeneic dendritic cells to the thymus during post-cyclosporine thymic regenerationQ70796858
Direct thymic involvement in anterior chamber-associated immune deviation: evidence for a nondeletional mechanism of centrally induced tolerance to extrathymic antigens in adult miceQ73082051
Differentiation of phagocytic monocytes into lymph node dendritic cells in vivoQ73336913
CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleenQ73520530
Human thymus contains 2 distinct dendritic cell populationsQ73586066
Age-dependent T cell tolerance and autoimmunity to myelin basic proteinQ73835283
Blood mononuclear cells induce regulatory NK T thymocytes in anterior chamber-associated immune deviationQ73894223
Induction of transplant tolerance with immunodominant allopeptide-pulsed host lymphoid and myeloid dendritic cellsQ74415746
Differentiation of monocytes into dendritic cells in a model of transendothelial traffickingQ77418711
Cyclosporin A-induced autologous graft-versus-host disease: a prototypical model of autoimmunity and active (dominant) tolerance coordinately induced by recent thymic emigrantsQ77823636
Donor-lymphocyte infusion induces transplantation tolerance by activating systemic and graft-infiltrating double-negative regulatory T cellsQ78385844
Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph nodeQ79326805
Semimature stage: a checkpoint in a dendritic cell maturation program that allows for functional reversion after signal-regulatory protein-alpha ligation and maturation signalsQ79401075
Antibody-induced transplantation tolerance that is dependent on thymus-derived regulatory T cellsQ82625686
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)607-622
P577publication date2009-03-09
P1433published inJournal of Experimental MedicineQ3186912
P1476titleThymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
P478volume206

Reverse relations

cites work (P2860)
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