Association of deletion allele of insertion/deletion polymorphism in α2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus.

scientific article published on 04 December 2012

Association of deletion allele of insertion/deletion polymorphism in α2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2147/TACG.S33814
P932PMC publication ID3681199
P698PubMed publication ID23776387

P50authorSafaa I TayelQ54257673
P2093author name stringWaleed A Ibrahim
Heba F Khader
Nesreen G El-Helbawy
P2860cites workThe insertion/deletion variation in the alpha2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetesQ24802084
Expression of alpha 2- and beta-adrenoceptor subtypes in human islets of LangerhansQ27867690
Global burden of hypertension: analysis of worldwide dataQ28302545
Heart disease and stroke statistics--2011 update: a report from the American Heart AssociationQ29547236
An insertion/deletion polymorphism in the α2b-adrenergic receptor gene is a novel genetic risk factor for acute coronary eventsQ57303695
Identification of a polymorphic glutamic acid stretch in the α2b-adrenergic receptor and lack of linkage with essential hypertensionQ57318987
Effect of a three-amino acid deletion in the α2B-adrenergic receptor gene on long-term body weight change in Finnish non-diabetic and type 2 diabetic subjectsQ61713503
A Simple Procedure for Human Lymphocyte Isolation from Peripheral BloodQ70496102
Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitusQ77678908
An insertion/deletion polymorphism in the alpha2B adrenoceptor gene is associated with peripheral neuropathy in patients with type 2 diabetes mellitusQ80363135
Hypertension awareness, treatment, and control--continued disparities in adults: United States, 2005-2006Q83710687
Selected major risk factors and global and regional burden of diseaseQ29614888
The vasodilatory actions of insulin on resistance and terminal arterioles and their impact on muscle glucose uptakeQ30312289
Identification of a three-amino acid deletion in the alpha2B-adrenergic receptor that is associated with reduced basal metabolic rate in obese subjectsQ33867916
Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblingsQ34084406
Linkage of essential hypertension to chromosome 18q.Q34132270
Functional variant in the (alpha)2B adrenoceptor gene, a positional candidate on chromosome 2, associates with hypertensionQ34292748
Association between a deletion/insertion polymorphism in the alpha2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention StudyQ34340929
Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cellsQ34586312
Physiological significance of alpha(2)-adrenergic receptor subtype diversity: one receptor is not enoughQ34744859
Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalitiesQ34996991
Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studiesQ35031678
Adrenergic receptor knockout mice: distinct functions of 9 receptor subtypesQ35632073
Noradrenergic pain modulationQ36618448
Association of insertion/deletion polymorphism of alpha-adrenoceptor gene in essential hypertension with or without type 2 diabetes mellitus in Malaysian subjectsQ36938156
Adrenergic Signaling Polymorphisms and Their Impact on Cardiovascular DiseaseQ37776088
International Union of Pharmacology nomenclature of adrenoceptorsQ40638526
Pharmacologic and therapeutic applications of alpha 2-adrenoceptor subtypesQ40710042
Genome-wide linkage analysis of systolic and diastolic blood pressure: the Québec Family StudyQ40743267
Alpha 2-adrenergic receptor gene polymorphism and hypertension in blacksQ41676928
Guidelines from the British Hypertension Society: BHS is set to bankrupt NHSQ42394025
An insertion/deletion polymorphism in the alpha2B adrenoceptor gene is associated with age at onset of type 2 diabetes mellitusQ44163397
Alpha(2B)-adrenergic receptor deletion polymorphism associates with autonomic nervous system activity in young healthy JapaneseQ44357235
A deletion in the alpha2B-adrenergic receptor gene and autonomic nervous function in central obesityQ47691630
A genome wide scan for early onset primary hypertension in ScandinaviansQ47697202
Insertion/insertion genotype of α2B-adrenergic receptor gene polymorphism is associated with silent myocardial ischemia in patients with type 2 diabetes mellitusQ49093167
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P921main subjecttype 2 diabetesQ3025883
P304page(s)111-118
P577publication date2012-12-04
P1433published inThe Application of Clinical GeneticsQ15817525
P1476titleAssociation of deletion allele of insertion/deletion polymorphism in α2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus
P478volume5

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cites work (P2860)
Q33844872Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes
Q64103561Neurally mediated syncope diagnosis based on adenylate cyclase activity in Japanese patients
Q33165592Relationship between human evolution and neurally mediated syncope disclosed by the polymorphic sites of the adrenergic receptor gene α2B-AR.

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