The antiphospholipid syndrome: still an enigma

scientific article published on December 2015

The antiphospholipid syndrome: still an enigma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/ASHEDUCATION-2015.1.53
P932PMC publication ID4877624
P698PubMed publication ID26637701
P5875ResearchGate publication ID285661583

P2093author name stringKeith R McCrae
Shruti Chaturvedi
P2860cites workPrevalence of antibodies to prothrombin in solid phase (aPT) and to phosphatidylserine-prothrombin complex (aPS/PT) in patients with and without lupus anticoagulantQ85743774
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Antiphospholipid syndrome and asymptomatic carriers of antiphospholipid antibody: prospective analysis of 404 individualsQ28210153
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Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patientsQ33341941
beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregationQ33375186
Prevention of murine antiphospholipid syndrome by BAFF blockadeQ33380975
A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndromeQ33404206
Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patientsQ33412915
Anti-beta2 glycoprotein I (beta2GPI) autoantibodies recognize an epitope on the first domain of beta2GPI.Q33504706
Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome.Q33576496
Epidemiology of the antiphospholipid antibody syndromeQ33916234
Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expressionQ34003992
The pathogenesis of the antiphospholipid syndromeQ34332601
Clinical significance of different antiphospholipid antibodies in the WAPS (warfarin in the antiphospholipid syndrome) studyQ34619943
CD28-B7-mediated T cell costimulation in chronic cardiac allograft rejection: differential role of B7-1 in initiation versus progression of graft arteriosclerosisQ35746486
Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodiesQ35977256
Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)Q36242479
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndromeQ36890849
Pediatric antiphospholipid antibodies and antiphospholipid syndromeQ37249533
Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndromeQ37473270
A prospective open-label pilot study of fluvastatin on proinflammatory and prothrombotic biomarkers in antiphospholipid antibody positive patientsQ37702168
Challenges in the diagnosis of the antiphospholipid syndromeQ37723113
Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patientsQ37803363
Antiphospholipid antibodies--we are not quite there yet.Q37829519
Antiphospholipid antibodies and the risk of recurrence after a first episode of venous thromboembolism: a systematic reviewQ38113968
Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximabQ38115382
Standardization of antiphospholipid antibody testing--historical perspectives and ongoing initiativesQ38182509
Primary prophylaxis to prevent obstetric complications in asymptomatic women with antiphospholipid antibodies: a systematic reviewQ38392607
Persistent antiphospholipid antibody (aPL) in asymptomatic carriers as a risk factor for future thrombotic events: a nationwide prospective studyQ39138695
Clinical course of high-risk patients diagnosed with antiphospholipid syndromeQ39934417
Thrombotic risk assessment in the antiphospholipid syndrome requires more than the quantification of lupus anticoagulantsQ43463817
The lupus anticoagulant: results from 2257 patients attending a high-risk pregnancy clinicQ43533979
Recent guidelines and recommendations for laboratory detection of lupus anticoagulantsQ43594150
Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study.Q43626449
A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndromeQ44588720
Antithrombotic effects of hydroxychloroquine in primary antiphospholipid syndrome patientsQ44830352
beta2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndromeQ45021710
IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosisQ45126748
Frequent false-positive results of lupus anticoagulant tests in plasmas of patients receiving the new oral anticoagulants and enoxaparinQ45220126
Update on the catastrophic antiphospholipid syndrome and the "CAPS Registry".Q45780878
The utility of the Taipan snake venom assay in assessing lupus anticoagulant status in individuals receiving or not receiving an oral vitamin K antagonist.Q45967639
Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the antiphospholipid syndromeQ47225448
Pregnancy complications in women with recurrent miscarriage associated with antiphospholipid antibodies treated with low dose aspirin and heparinQ47868175
The CAPS Registry: morbidity and mortality of the catastrophic antiphospholipid syndrome.Q53189388
Update of the guidelines for lupus anticoagulant detection. Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis.Q53190445
Failure of dabigatran and rivaroxaban to prevent thromboembolism in antiphospholipid syndrome: a case series of three patientsQ57907773
Eculizumab Prevents Recurrent Antiphospholipid Antibody Syndrome and Enables Successful Renal TransplantationQ58048140
Rivaroxaban and false positive lupus anticoagulant testingQ60619095
Observational study of pregnant women with a previous spontaneous abortion before the 10th gestation week with and without antiphospholipid antibodiesQ61853563
Laboratory diagnosis of lupus anticoagulants for patients on oral anticoagulant treatment. Performance of dilute Russell viper venom test and silica clotting time in comparison with Staclot LAQ78321143
Lupus anticoagulants and the risk of a first episode of deep venous thrombosisQ81064718
Detection of lupus anticoagulant in the presence of rivaroxaban using Taipan snake venom timeQ84349009
The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter studyQ84438431
An international multicentre‐laboratory evaluation of a new assay to detect specifically lupus anticoagulants dependent on the presence of anti‐beta2‐glycoprotein autoantibodiesQ85100865
P921main subjectantiphospholipid syndromeQ582207
P304page(s)53-60
P577publication date2015-12-01
P1433published inHematology / the Education Program of the American Society of HematologyQ26842068
P1476titleThe antiphospholipid syndrome: still an enigma
P478volume2015

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cites work (P2860)
Q36303250Cardiovascular risk factors are major determinants of thrombotic risk in patients with the lupus anticoagulant
Q38827909Complement inhibition with eculizumab for thrombotic microangiopathy rescues a living-donor kidney transplant in a patient with antiphospholipid antibody syndrome
Q47982275Diagnosis and management of the antiphospholipid syndrome
Q49968681Mechanisms and management of thrombosis and bleeding in antiphospholipid syndrome
Q90241448Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment
Q36867309Neutrophil extracellular traps - the dark side of neutrophils
Q58551653Obstetric antiphospholipid syndrome
Q59791491Presence of Immune Complexes of IgG/IgM Bound to B2-glycoprotein I Is Associated With Non-criteria Clinical Manifestations in Patients With Antiphospholipid Syndrome

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