Drug addiction as a pathology of staged neuroplasticity

scientific article published on 05 September 2007

Drug addiction as a pathology of staged neuroplasticity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.NPP.1301564
P698PubMed publication ID17805308
P5875ResearchGate publication ID6035793

P2093author name stringPeter W Kalivas
Charles O'Brien
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The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.Q43770574
Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patientsQ43873742
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A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in ratsQ44222954
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectneuroplasticityQ849491
substance dependenceQ3378593
pathologyQ7208
P304page(s)166-180
P577publication date2007-09-05
P1433published inNeuropsychopharmacologyQ2261280
P1476titleDrug addiction as a pathology of staged neuroplasticity
P478volume33

Reverse relations

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Q36746407Impact of partial dopamine depletion on cognitive flexibility in BDNF heterozygous mice
Q40973001In silico identification and in vivo validation of miR-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens.
Q43009526Individual differences in nucleus accumbens dopamine receptors predict development of addiction-like behavior: a computational approach.
Q36554730Induction of innate immune genes in brain create the neurobiology of addiction
Q36978463Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats
Q37293644Interactive effects of ethanol and nicotine on learning in C57BL/6J mice depend on both dose and duration of treatment
Q77717779Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
Q48249065Levodopa prevents the reinstatement of cocaine self-administration in rats via potentiation of dopamine release in the medial prefrontal cortex.
Q37384969Long-term effects of cocaine experience on neuroplasticity in the nucleus accumbens core of addiction-prone rats.
Q88027758Machine Learning of Functional Magnetic Resonance Imaging Network Connectivity Predicts Substance Abuse Treatment Completion
Q30431556Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats
Q34091899Measuring addiction propensity and severity: the need for a new instrument
Q55236584Mechanisms Underlying the Risk to Develop Drug Addiction, Insights From Studies in Drosophila melanogaster.
Q37730644Mechanisms of illness progression in the recurrent affective disorders
Q28539236Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level
Q55505653Melatonin in drug addiction and addiction management: Exploring an evolving multidimensional relationship.
Q33739510Metabolite levels in the brain reward pathway discriminate those who remain abstinent from those who resume hazardous alcohol consumption after treatment for alcohol dependence
Q22248089Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens
Q36723555MicroRNAs Are Involved in the Development of Morphine-Induced Analgesic Tolerance and Regulate Functionally Relevant Changes in Serpini1.
Q47232576Minding the brain: the role of pharmacotherapy in substance-use disorder treatment
Q42374658Modeling Causal Relationships among Brain Areas in the Mesocorticolimbic System during Resting-State in Cocaine Users Utilizing a Graph Theoretic Approach
Q30430917Modulation of risky choices in recently abstinent dependent cocaine users: a transcranial direct-current stimulation study
Q37325137Molecular mechanisms of psychostimulant-induced structural plasticity
Q48462251Morphine-induced locomotor sensitization produces structural plasticity in the mesocorticolimbic system dependent on CB1-R activity
Q37140681N-Acetylcysteine reverses cocaine-induced metaplasticity
Q55887376N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility
Q39036583NCAM signaling mediates the effects of GDNF on chronic morphine-induced neuroadaptations
Q30485956Narp deletion blocks extinction of morphine place preference conditioning.
Q22251254Natural rewards, neuroplasticity, and non-drug addictions
Q50656042Negative reinforcement via motivational withdrawal is the driving force behind the transition to addiction.
Q37491517Neural correlates of reward-based spatial learning in persons with cocaine dependence
Q24647156Neurocircuitry of addiction
Q24631230Neuroimaging and drug taking in primates
Q37629743Neuronal extracellular signal-regulated kinase (ERK) activity as marker and mediator of alcohol and opioid dependence
Q34224871Neuronal mechanisms underlying development of nicotine dependence: implications for novel smoking-cessation treatments.
Q48797991Neuronal metabolomics by ion mobility mass spectrometry in cocaine self-administering rats after early and late withdrawal.
Q37028692Neuronal pentraxins modulate cocaine-induced neuroadaptations.
Q43052876Neuropharmacology of addiction--setting the scene
Q26799795Neuroplasticity and Predictors of Alcohol Recovery
Q38060713Neuroplasticity in addiction: cellular and transcriptional perspectives.
Q37111631Neuroplasticity in the mesolimbic dopamine system and cocaine addiction
Q36335668Neuroplasticity, axonal guidance and micro-RNA genes are associated with morphine self-administration behavior
Q26782204Neuroscience of Internet Pornography Addiction: A Review and Update
Q37223964Neurotrophic factors and structural plasticity in addiction
Q37720520Noninvasive brain stimulation to suppress craving in substance use disorders: Review of human evidence and methodological considerations for future work
Q47301293On Mourning and Recovery: Integrating Stages of Grief and Change Toward a Neuroscience-Based Model of Attachment Adaptation in Addiction Treatment.
Q33859178Open label smoking cessation with varenicline is associated with decreased glutamate levels and functional changes in anterior cingulate cortex: preliminary findings
Q50023605Opioid and Psychostimulant Plasticity: Targeting Overlap in Nucleus Accumbens Glutamate Signaling
Q34660762Optogenetic dissection of medial prefrontal cortex circuitry
Q30585757Orbitofrontal activation restores insight lost after cocaine use.
Q35572211Orexin-1 receptor signaling increases motivation for cocaine-associated cues
Q36386187Orexin/hypocretin (Orx/Hcrt) transmission and drug-seeking behavior: is the paraventricular nucleus of the thalamus (PVT) part of the drug seeking circuitry?
Q52317594PET Imaging Reveals Brain Metabolic Changes in Adolescent Rats Following Chronic Escalating Morphine Administration.
Q47574337Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand
Q36700620Pharmacologic mechanisms of crystal meth
Q37708082Pharmacological approaches to reducing craving in patients with alcohol use disorders
Q34253787Pharmacotherapeutics directed at deficiencies associated with cocaine dependence: focus on dopamine, norepinephrine and glutamate.
Q26991936Pharmacotherapy of amphetamine-type stimulant dependence: an update
Q24630570Playing video games while using or feeling the effects of substances: associations with substance use problems
Q39094898Posttraumatic Stress Disorder and Alcohol Use Disorder: A Critical Review of Pharmacologic Treatments
Q37821388Prefrontal cortical regulation of drug seeking in animal models of drug relapse
Q41947211Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli
Q36989489Prospective associations between brain activation to cocaine and no-go cues and cocaine relapse
Q30440436Protracted manifestations of acute dependence after a single morphine exposure
Q46887044REVIEW OF HEYMAN'S ADDICTION: A DISORDER OF CHOICE.
Q34518254Regional expression of extracellular signal-regulated kinase 1 and 2 mRNA in a morphine-induced conditioned place preference model
Q34820236Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference
Q99413708Regulation of dopamine-dependent transcription and cocaine action by Gadd45b
Q36617971Reinstatement of ethanol and sucrose seeking by the neurosteroid allopregnanolone in C57BL/6 mice.
Q42205203Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex.
Q35110324Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport
Q30474258Repeated intravenous cocaine experience: development and escalation of pre-drug anticipatory 50-kHz ultrasonic vocalizations in rats
Q52317578Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking.
Q41958181Restructuring Reward Mechanisms in Nicotine Addiction: A Pilot fMRI Study of Mindfulness-Oriented Recovery Enhancement for Cigarette Smokers.
Q37221894Review. Psychological and neural mechanisms of relapse
Q34798207Review. The incentive sensitization theory of addiction: some current issues
Q57476791Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence
Q27013753Role of nucleus accumbens glutamatergic plasticity in drug addiction
Q38891009Role of perineuronal nets in the anterior dorsal lateral hypothalamic area in the acquisition of cocaine-induced conditioned place preference and self-administration
Q58614784Role of prefrontal cortex in the extinction of drug memories
Q28066246Romantic Love vs. Drug Addiction May Inspire a New Treatment for Addiction
Q91494247Selective dopamine D3 receptor antagonist YQA14 inhibits morphine-induced behavioral sensitization in wild type, but not in dopamine D3 receptor knockout mice
Q59899903Selective effects of Δ9-tetrahydrocannabinol on medium spiny neurons in the striatum
Q58110631Self-regulation of the dopaminergic reward circuit in cocaine users with mental imagery and neurofeedback
Q37071408Serotonergic mechanisms in addiction-related memories
Q34485446Sex differences in drug addiction and response to exercise intervention: From human to animal studies
Q44348359Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex
Q30360185Single prolonged stress effects on sensitization to cocaine and cocaine self-administration in rats.
Q46233795Single session of cocaine intravenous self-administration shapes goal-oriented behaviours and up-regulates Arc mRNA levels in rat medial prefrontal cortex.
Q33774571Sleep disturbance as a universal risk factor for relapse in addictions to psychoactive substances
Q57492385Smoking Cessation With 20 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Applied to Two Brain Regions: A Pilot Study
Q37001135Social Isolation Blunted the Response of Mesocortical Dopaminergic Neurons to Chronic Ethanol Voluntary Intake
Q50498125Sodium butyrate modulates a methamphetamine-induced conditioned place preference.
Q28397558Striatal microRNA controls cocaine intake through CREB signalling
Q28392093Striatal signal transduction and drug addiction
Q38287920Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine.
Q33966766Synapse density and dendritic complexity are reduced in the prefrontal cortex following seven days of forced abstinence from cocaine self-administration
Q41489097THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction.
Q37082575Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction
Q38124378Targeting midkine and pleiotrophin signalling pathways in addiction and neurodegenerative disorders: recent progress and perspectives.
Q33821312Targeting the glutamatergic system to treat pathological gambling: current evidence and future perspectives.
Q42176631Temporally dependent changes in cocaine-induced synaptic plasticity in the nucleus accumbens shell are reversed by D1-like dopamine receptor stimulation
Q26824406The "stop" and "go" of nicotine dependence: role of GABA and glutamate
Q33788985The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats
Q56457243The Emperor Has No Clothes: A Review of the ‘Pornography Addiction’ Model
Q42565054The Extracellular Matrix Protein Brevican Limits Time-Dependent Enhancement of Cocaine Conditioned Place Preference.
Q36578522The HIV-1 transgenic rat model of neuroHIV.
Q36529100The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency
Q57001579The Marriage of Phenomics and Genetical Genomics: A Systems Approach to Complex Trait Analysis
Q34510753The Nociceptin Receptor as an Emerging Molecular Target for Cocaine Addiction
Q39774189The Role of AMPAR Trafficking Mediated by Neuronal Pentraxins in Cocaine-induced Neuroadaptations.
Q34317475The contribution of brain reward circuits to the obesity epidemic
Q26824011The downward spiral of chronic pain, prescription opioid misuse, and addiction: cognitive, affective, and neuropsychopharmacologic pathways
Q37121626The effects of cocaine on different redox forms of cysteine and homocysteine, and on labile, reduced sulfur in the rat plasma following active versus passive drug injections.
Q47597316The effects of morphine treatment on the NCAM and its signaling in the MLDS of rats
Q39563244The effects of social contact on cocaine intake under extended-access conditions in male rats
Q33905665The emergence of gonadal hormone influences on dopaminergic function during puberty
Q43075979The genetic epidemiology of substance use disorder: A review
Q37538517The glutamate homeostasis hypothesis of addiction
Q36981928The impact of orbitofrontal dysfunction on cocaine addiction
Q34440064The interactive effects of environmental enrichment and extinction interventions in attenuating cue-elicited cocaine-seeking behavior in rats
Q35833718The mGluR5 Positive Allosteric Modulator CDPPB Does Not Alter Extinction or Contextual Reinstatement of Methamphetamine-Seeking Behavior in Rats
Q28534521The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice
Q38672600The motor way: Clinical implications of understanding and shaping actions with the motor system in autism and drug addiction
Q28236333The neurocircuitry of illicit psychostimulant addiction: acute and chronic effects in humans
Q37603518The regulation of neuronal gene expression by alcohol.
Q36610043The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behavior
Q42269239Thorndike's Law 2.0: Dopamine and the Regulation of Thrift.
Q30382513Thyroid receptor β involvement in the effects of acute nicotine on hippocampus-dependent memory.
Q90165538Transcranial Direct Current Stimulation Applied to the Dorsolateral and Ventromedial Prefrontal Cortices in Smokers Modifies Cognitive Circuits Implicated in the Nicotine Withdrawal Syndrome
Q35205844Transcranial direct current stimulation in psychiatric disorders
Q103834519Transcranial magnetic stimulation neurophysiology of patients with major depressive disorder: a systematic review and meta-analysis
Q90654287Translational dynamics of alcohol tolerance of preclinical models and human laboratory studies
Q38129470Varenicline and neuronal nicotinic acetylcholine receptors: a new approach to the treatment of co-occurring alcohol and nicotine addiction?
Q34063548Ventral and dorsal striatal dopamine efflux and behavior in rats with simple vs. co-morbid histories of cocaine sensitization and neonatal ventral hippocampal lesions
Q34037180Viral-mediated expression of extracellular signal-regulated kinase-2 in the ventral tegmental area modulates behavioral responses to cocaine
Q34022307Water-soluble coenzyme Q10 formulation (Q-TER(®)) in the treatment of presbycusis
Q50435607Water-soluble coenzyme Q10 formulation in presbycusis: long-term effects.
Q34873448Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption
Q48071032Youth Depression Alleviation-Augmentation with an anti-inflammatory agent (YoDA-A): protocol and rationale for a placebo-controlled randomized trial of rosuvastatin and aspirin.
Q39036076ZNF804A variants confer risk for heroin addiction and affect decision making and gray matter volume in heroin abusers
Q39678425beta-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist
Q33552502rTMS in the treatment of drug addiction: an update about human studies
Q90637944rTMS-Induced Changes in Glutamatergic and Dopaminergic Systems: Relevance to Cocaine and Methamphetamine Use Disorders
Q47827427μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons.