Improved cell metabolism prolongs photoreceptor survival upon retinal-pigmented epithelium loss in the sodium iodate induced model of geographic atrophy

scientific article published on 11 February 2016

Improved cell metabolism prolongs photoreceptor survival upon retinal-pigmented epithelium loss in the sodium iodate induced model of geographic atrophy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.7330
P932PMC publication ID4891071
P698PubMed publication ID26883199

P2093author name stringClaudio Punzo
Marina Zieger
P2860cites workChoice of Cell Source in Cell-Based Therapies for Retinal Damage due to Age-Related Macular Degeneration: A ReviewQ21284849
Age-Related Macular Degeneration: Advances in Management and DiagnosisQ26799617
RPE necroptosis in response to oxidative stress and in AMDQ27693234
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cellsQ28204697
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studiesQ28252926
The Project MACULA Retinal Pigment Epithelium Grading System for Histology and Optical Coherence Tomography in Age-Related Macular DegenerationQ28645952
Prevalence of age-related macular degeneration in the United StatesQ29614964
Activation of a metabolic gene regulatory network downstream of mTOR complex 1Q29615179
Retinal gene delivery by rAAV and DNA electroporationQ30539515
Direct effect of sodium iodate on neurosensory retina.Q33727104
Histopathology of age-related macular degenerationQ33774161
Strain difference in photoreceptor cell death after retinal detachment in mice.Q33872390
Spare the rods, save the cones in aging and age-related maculopathyQ33967294
Photoreceptor topography in ageing and age-related maculopathyQ34307036
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophyQ34891582
Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degenerationQ35005946
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.Q35118257
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa miceQ35409026
Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patientsQ35623846
Disappearance of extramacular drusen after chronic retinal detachmentQ35920854
The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypesQ36035008
Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complexQ36083881
The retinal pigment epithelium in visual functionQ36178984
The epidemiology of retinal reticular drusenQ36482609
Relationship between RPE and choriocapillaris in age-related macular degenerationQ36791715
Geographic atrophy: a histopathological assessmentQ36860952
Geographic atrophy: clinical features and potential therapeutic approachesQ38179138
Causes of vision loss worldwide, 1990-2010: a systematic analysisQ38238049
Stem cell therapy for retinal diseasesQ38332500
Rhodopsin-iCre transgenic mouse line for Cre-mediated rod-specific gene targeting.Q40449714
Survival factors in retinal degenerationsQ40563558
Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival.Q41051208
Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosaQ41967871
Sodium iodate selectively injuries the posterior pole of the retina in a dose-dependent manner: morphological and electrophysiological studyQ42105166
Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman LectureQ42483851
Labeling cytoskeletal F-actin with rhodamine phalloidin or fluorescein phalloidin for imagingQ43075500
Age-related macular degeneration revisited--piecing the puzzle: the LXIX Edward Jackson memorial lectureQ43560026
Targeted expression of Cre recombinase to cone photoreceptors in transgenic miceQ45213774
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.Q46011005
Decreased visual function after patchy loss of retinal pigment epithelium induced by low-dose sodium iodateQ46064849
Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration.Q46710946
Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation.Q50611046
Quantifying spatial correlations of fluorescent markers using enhanced background reduction with protein proximity index and correlation coefficient estimations.Q53089446
Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the ratQ57612087
Evolution of geographic atrophy of the retinal pigment epitheliumQ69099160
Photoreceptor loss in age-related macular degenerationQ71104955
Immunocytochemical analyses of distributions of Na, K-ATPase and GLUT1, insulin and transferrin receptors in the developing retinal pigment epithelial cellsQ72149308
Mouse opsin promoter-directed Cre recombinase expression in transgenic miceQ83197208
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectphotoreceptor proteinQ7187894
geographic atrophyQ47200750
P304page(s)9620-9633
P577publication date2016-02-11
P1433published inOncotargetQ1573155
P1476titleImproved cell metabolism prolongs photoreceptor survival upon retinal-pigmented epithelium loss in the sodium iodate induced model of geographic atrophy
P478volume7

Reverse relations

cites work (P2860)
Q37190609Advances in Gene Therapy for Diseases of the Eye.
Q55274674Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa.
Q38767261Cell-based therapeutic strategies for replacement and preservation in retinal degenerative diseases
Q37481357Gene therapy approaches for the treatment of retinal disorders
Q47146168Loss of the cone-enriched caspase-7 does not affect secondary cone death in retinitis pigmentosa
Q41436382Monocyte infiltration and proliferation reestablish myeloid cell homeostasis in the mouse retina following retinal pigment epithelial cell injury
Q60046798Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice
Q37412537TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome

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