Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats.

scientific article published on 07 June 2016

Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1033287285
P356DOI10.1186/S12967-016-0908-7
P932PMC publication ID4897890
P698PubMed publication ID27268027

P50authorPiercarlo Sarzi-PuttiniQ30002194
Maria Rita GismondoQ40791898
P2093author name stringAlessandra Lombardi
Enzo Massimo Caruso
Salvatore Santandrea
Franco Montrone
Innocenzo Caruso
P2860cites workThe american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritisQ27860872
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[Rheumatoid synovitis of the knee, treated successfully with intra-articular rifamycin SV]Q70316830
Rifamycin SV administered by intra-articular infiltrations shows disease modifying activity in patients with pauci- or polyarticular juvenile rheumatoid arthritisQ72252839
Rifamycin SV versus triamcinolone in local treatment of rheumatoid synovitisQ72891612
Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependentQ78025335
Depressed proliferative responses by peripheral blood mononuclear cells from early arthritis patients to mycobacterial heat shock protein 60Q78169200
Do all drugs and treatments for rheumatoid arthritis have the same efficacy?Q81138145
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The involvement of heat-shock proteins in the pathogenesis of autoimmune arthritis: a critical appraisalQ36079214
B cells: a fundamental role in the pathogenesis of rheumatoid arthritis?Q36106119
T cell epitope-specific immune therapy for rheumatic diseasesQ36356746
A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environmentQ36577387
The role of B cells in animal models of rheumatoid arthritisQ36664672
Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritisQ37356882
Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycansQ37525926
Innate immunity and rheumatoid arthritisQ37761419
B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectivesQ37903458
The ins and outs of MHC class II-mediated antigen processing and presentationQ38365560
Injection of the rheumatoid knee: does intra-articular methotrexate or rifampicin add to the benefits of triamcinolone hexacetonide?Q39445380
Rheumatoid knee synovitis successfully treated with intra-articular rifamycin SV.Q41129052
Twenty years of experience with intra-articular rifamycin for chronic arthritidesQ41680058
Presence of human 65 kD heat shock protein (hsp) in inflamed joints and subcutaneous nodules of RA patientsQ41822323
Epitope-specific immunotherapy of rheumatoid arthritis: clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase IQ41937377
The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10.Q43872556
TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritisQ44663546
Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritisQ45304911
Pan-DR-binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis.Q46020051
Rifamycin SV in the Treatment of Knee SynovitisQ46789755
American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritisQ47643186
In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients.Q50193209
A theory of regulation and self-nonself discrimination in an immune network.Q52244772
Clinical improvement in ankylosing spondylitis with rifamycin SV infiltrations of peripheral joints.Q54065722
Rifamycin SV in local treatment of synovitis--a clinical, arthroscopic and pharmacologic evaluation.Q54253660
Treatment of adjuvant arthritis in rats: Vaccination potential of a synthetic nonapeptide from the 65 kDa heat shock protein of mycobacteriaQ67657519
Prevention of appearance of radiological lesions in early rheumatoid arthritis: a randomized, single-blind study comparing intra-articular rifamycin with auranofinQ68100655
P433issue1
P921main subjectrheumatoid arthritisQ187255
P304page(s)162
P577publication date2016-06-07
P1433published inJournal of Translational MedicineQ15716664
P1476titleVaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats
P478volume14