Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway

scientific article published on December 2008

Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200807151
P932PMC publication ID2592822
P698PubMed publication ID19047466
P5875ResearchGate publication ID23560399

P50authorDavid WilkinsonQ42712968
P2093author name stringAlexei Poliakov
Andrea Pasini
Maria L Cotrina
P2860cites workEphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxisQ24316344
Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval developmentQ24336986
The bimodal regulation of epidermal growth factor signaling by human Sprouty proteinsQ24534190
Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signallingQ24534484
Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expressionQ24562198
Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responsesQ28143168
Boundaries in development: formation and functionQ28202940
SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptorQ28207588
Mechanisms and functions of Eph and ephrin signallingQ28208291
Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activityQ28217897
The ephrins and Eph receptors in neural developmentQ28266706
Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesisQ28286738
Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligandsQ28294023
EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathwayQ28505876
Targets of fibroblast growth factor 1 (FGF-1) and FGF-2 signaling involved in the invasive and tumorigenic behavior of carcinoma cellsQ28575842
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fateQ28576088
Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryoQ28584770
Regulation of repulsion versus adhesion by different splice forms of an Eph receptorQ28589811
Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loopsQ28609624
Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor SignalingQ28609932
EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphataseQ28647621
The molecular biology of axon guidanceQ29617857
Eph receptor signalling casts a wide net on cell behaviourQ29619988
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor functionQ30303639
State-dependent Ras signaling and AMPA receptor traffickingQ30437816
Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retractionQ31813080
Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrinsQ33178119
The genetics of cell migration in Drosophila melanogaster and Caenorhabditis elegans development.Q33664605
Fibroblast growth factor receptor-mediated rescue of x-ephrin B1-induced cell dissociation in Xenopus embryosQ33961672
Adaptation in the chemotactic guidance of nerve growth conesQ34126381
Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B.Q34158339
Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsionQ34230386
Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domainsQ34245285
Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth conesQ34486134
Stabilizing the regionalisation of the developing vertebrate central nervous systemQ34631758
Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidanceQ35099606
Modulation of signalling by Sprouty: a developing storyQ35790325
MAP kinases and cell migrationQ35889220
Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assemblyQ35911289
An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegansQ35963706
Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary glandQ36325197
Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.Q36336041
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motilityQ39714519
Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsionQ39714662
Dual effects of Sprouty1 on TCR signaling depending on the differentiation state of the T cellQ40284414
Silencing of EphA3 through a cis interaction with ephrinA5.Q40313686
EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processingQ40316428
Retinal axon response to ephrin-as shows a graded, concentration-dependent transition from growth promotion to inhibitionQ40548457
Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathwayQ40808897
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphataseQ42453925
EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion.Q42795950
Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O.Q42802380
Distinct neurite outgrowth signaling pathways converge on ERK activationQ42814940
The C. elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis.Q43963581
An inducible system for the study of FGF signalling in early amphibian development.Q44373975
Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth conesQ44386910
EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagationQ44419417
Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways.Q44728323
Inhibition of FGF receptor activity in retinal ganglion cell axons causes errors in target recognitionQ44731100
Ephrin-B ligands play a dual role in the control of neural crest cell migration.Q45221973
Eph and NMDA receptors control Ca2+/calmodulin-dependent protein kinase II activation during C. elegans oocyte meiotic maturation.Q46788512
Eph receptors inactivate R-Ras through different mechanisms to achieve cell repulsionQ46979653
Eph receptors and ephrins restrict cell intermingling and communicationQ48164807
Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axonsQ48219540
Fibroblast growth factors 2 and 4 stimulate migration of mouse embryonic limb myogenic cells.Q50528322
Ephrin-Eph signalling drives the asymmetric division of notochord/neural precursors in Ciona embryos.Q51992543
Sprouty, an intracellular inhibitor of Ras signaling.Q52569025
Cell-cell adhesion in limb-formation, estimated from photographs of cell sorting experiments based on a spatial stochastic modelQ57065524
Chemotactic migration of mesencephalic neural crest cells in the mouseQ73519299
EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cellsQ74211173
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P1104number of pages15
P304page(s)933-947
P577publication date2008-12-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleRegulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway
P478volume183

Reverse relations

cites work (P2860)
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Q27314495Variable combinations of specific ephrin ligand/Eph receptor pairs control embryonic tissue separation
Q35849356miR-27b controls venous specification and tip cell fate

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