Flexibility of Vibrio cholerae ToxT in transcription activation of genes having altered promoter spacing

scientific article published on 10 October 2008

Flexibility of Vibrio cholerae ToxT in transcription activation of genes having altered promoter spacing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.00512-08
P932PMC publication ID2593237
P698PubMed publication ID18849430

P50authorJeffrey WitheyQ42866026
P2093author name stringMichelle Bellair
P2860cites workRegulatory cascade controls virulence in Vibrio choleraeQ24564679
Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonizationQ28276944
TcpP protein is a positive regulator of virulence gene expression in Vibrio choleraeQ28485708
Arac/XylS family of transcriptional regulatorsQ28776772
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extensionQ29547330
A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strainsQ30429822
Lysogenic conversion by a filamentous phage encoding cholera toxinQ34062735
Degradation of the membrane-localized virulence activator TcpP by the YaeL protease in Vibrio choleraeQ34132245
Vibrio cholerae and cholera: out of the water and into the hostQ34133834
Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genesQ34150905
The AraC transcriptional activatorsQ34204972
Promoter structure, promoter recognition, and transcription activation in prokaryotes.Q34328218
The Vibrio cholerae toxin-coregulated-pilus gene tcpI encodes a homolog of methyl-accepting chemotaxis proteinsQ34528567
The Vibrio cholerae acfB colonization determinant encodes an inner membrane protein that is related to a family of signal-transducing proteinsQ34533198
Genetic analysis of the interaction between Vibrio cholerae transcription activator ToxR and toxT promoter DNAQ35602653
Virstatin inhibits dimerization of the transcriptional activator ToxTQ35844578
The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activatorsQ36132704
Expression of the Vibrio cholerae gene encoding aldehyde dehydrogenase is under control of ToxR, the cholera toxin transcriptional activatorQ36145738
Regulatory networks controlling Vibrio cholerae virulence gene expressionQ36313974
Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio choleraeQ38303981
The Vibrio cholerae ToxR/TcpP/ToxT virulence cascade: distinct roles for two membrane-localized transcriptional activators on a single promoterQ38307608
A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strainsQ38350074
The arrangement of subunits in cholera toxinQ39080478
Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoterQ39694798
Toxin-coregulated pilus, but not mannose-sensitive hemagglutinin, is required for colonization by Vibrio cholerae O1 El Tor biotype and O139 strainsQ39825538
Improved vector system for constructing transcriptional fusions that ensures independent translation of lacZ.Q39943972
Identification of a pilus colonization factor that is coordinately regulated with cholera toxinQ41817439
Organization of tcp, acf, and toxT genes within a ToxT-dependent operonQ42478743
Sequence analysis of the Vibrio cholerae acfD gene reveals the presence of an overlapping reading frame, orfZ, which encodes a protein that shares sequence similarity to the FliA and FliC products of SalmonellaQ42599737
Isolation and characterization of the Vibrio cholerae acfA gene, required for efficient intestinal colonizationQ42683651
Isolation and characterization of a Vibrio cholerae gene (tagA) that encodes a ToxR-regulated lipoproteinQ42691364
The toxbox: specific DNA sequence requirements for activation of Vibrio cholerae virulence genes by ToxT.Q44245560
Novel protein--protein interaction between Escherichia coli SoxS and the DNA binding determinant of the RNA polymerase alpha subunit: SoxS functions as a co-sigma factor and redeploys RNA polymerase from UP-element-containing promoters to SoxS-depenQ45090322
Characterization of functional domains of the Vibrio cholerae virulence regulator ToxT.Q46785725
Versatility of the carboxy-terminal domain of the alpha subunit of RNA polymerase in transcriptional activation: use of the DNA contact site as a protein contact site for MarA.Q53883822
CholeraQ57116811
Activation of both acfA and acfD transcription by Vibrio cholerae ToxT requires binding to two centrally located DNA sites in an inverted repeat conformationQ57971387
DNA-binding characteristics of theEscherichia coliCytR regulator: a relaxed spacing requirement between operator half-sites is provided by a flexible, unstructured interdomain linkerQ60954813
Regulation of gene expression in Vibrio cholerae by ToxT involves both antirepression and RNA polymerase stimulationQ64449517
Subunit structure of cholera toxinQ67251704
Gene splicing by overlap extensionQ70662421
Interdependence of the position and orientation of SoxS binding sites in the transcriptional activation of the class I subset of Escherichia coli superoxide-inducible promotersQ73189452
Structural requirements for marbox function in transcriptional activation of mar/sox/rob regulon promoters in Escherichia coli: sequence, orientation and spatial relationship to the core promoterQ73189454
DNA binding and ToxR responsiveness by the wing domain of TcpP, an activator of virulence gene expression in Vibrio choleraeQ73727087
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectVibrio choleraeQ160821
P304page(s)7925-7931
P577publication date2008-10-10
P1433published inJournal of BacteriologyQ478419
P1476titleFlexibility of Vibrio cholerae ToxT in transcription activation of genes having altered promoter spacing
P478volume190

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cites work (P2860)
Q34853660A small unstructured region in Vibrio cholerae ToxT mediates the response to positive and negative effectors and ToxT proteolysis
Q42264912Analysis of Helicobacter pylori cagA promoter elements required for salt-induced upregulation of CagA expression
Q43045024Bicarbonate increases binding affinity of Vibrio cholerae ToxT to virulence gene promoters
Q41871341Genetic screening for bacterial mutants in liquid growth media by fluorescence-activated cell sorting.
Q89636193HilD, HilC, and RtsA Form Homodimers and Heterodimers to Regulate Expression of the Salmonella Pathogenicity Island I Type III Secretion System
Q42072559Identification and characterization of the functional toxboxes in the Vibrio cholerae cholera toxin promoter.
Q27659552Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes
Q57971381Termination of Vibrio cholerae virulence gene expression is mediated by proteolysis of the major virulence activator, ToxT
Q28485717The Vibrio cholerae fatty acid regulatory protein, FadR, represses transcription of plsB, the gene encoding the first enzyme of membrane phospholipid biosynthesis
Q37854314The complexity of ToxT-dependent transcription in Vibrio cholerae
Q40340387Transcriptional Repression of the VC2105 Protein by Vibrio FadR Suggests that It Is a New Auxiliary Member of the fad Regulon

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