Lyme borreliosis spirochete Erp proteins, their known host ligands, and potential roles in mammalian infection

scientific article published on 11 January 2008

Lyme borreliosis spirochete Erp proteins, their known host ligands, and potential roles in mammalian infection is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/J.IJMM.2007.09.004
P932PMC publication ID2596196
P698PubMed publication ID18248770
P5875ResearchGate publication ID5603153

P2093author name stringSean P Riley
Brian Stevenson
Catherine A Brissette
Anne E Cooley
Michael E Woodman
Tomasz Bykowski
Ashutosh Verma
Logan H Burns
P2860cites workDeletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndromeQ21145235
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferiQ22122357
Form and function: the laminin family of heterotrimersQ22254277
Borrelia burgdorferi erp proteins are immunogenic in mammals infected by tick bite, and their synthesis is inducible in cultured bacteria.Q24522402
Identification of human complement Factor H as a ligand for L-selectinQ24531529
Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochetesQ24537183
LfhA, a novel factor H-binding protein of Leptospira interrogansQ24547681
A newly identified leptospiral adhesin mediates attachment to lamininQ24673674
Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme diseaseQ24676083
Borrelia burgdorferi binding of host complement regulator factor H is not required for efficient mammalian infectionQ24684907
Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modellingQ27632511
Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparinQ28141946
A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferiQ28144621
Plasma lipopolysaccharide-binding protein is found associated with a particle containing apolipoprotein A-I, phospholipid, and factor H-related proteinsQ28282116
Comparison of surface recognition and C3b binding properties of mouse and human complement factor HQ28505240
Analysis of promoter elements involved in the transcriptional initiation of RpoS-dependent Borrelia burgdorferi genesQ29346537
The relapsing fever spirochete Borrelia hermsii contains multiple, antigen-encoding circular plasmids that are homologous to the cp32 plasmids of Lyme disease spirochetesQ30881145
Differences of two Borrelia burgdorferi strains in complement activation and serum resistanceQ31004819
Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein familyQ31134023
Serum-resistant strains of Borrelia burgdorferi evade complement-mediated killing by expressing a CD59-like complement inhibitory moleculeQ31134574
Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory miceQ32063128
Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosisQ32063131
Two factor H-related proteins from the mouse: expression analysis and functional characterizationQ33259755
Localization of Borrelia burgdorferi in murine Lyme borreliosis by electron microscopyQ72582950
Persistence of Borrelia burgdorferi in ligamentous tissue from a patient with chronic Lyme borreliosisQ72607871
The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferiQ73288780
Fibrinogen is a component of a novel lipoprotein particle: factor H-related protein (FHRP)-associated lipoprotein particle (FALP)Q73295206
Heterogeneity in the complement-dependent bacteriolysis within the species of Borrelia burgdorferiQ73313091
Surface exposure and protease insensitivity of Borrelia burgdorferi Erp (OspEF-related) lipoproteinsQ73703330
Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and Factor HQ73955072
Human polymorphonuclear leukocytes adhere to complement factor H through an interaction that involves alphaMbeta2 (CD11b/CD18)Q74477297
Complement resistance in Borrelia burgdorferi strain 297: outer membrane proteins prevent MAC formation at lysis susceptible sitesQ77890743
Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor HQ78625995
Functional characterization of BbCRASP-2, a distinct outer membrane protein of Borrelia burgdorferi that binds host complement regulators factor H and FHL-1Q80151917
The host immune regulator factor H interacts via two contact sites with the PspC protein of Streptococcus pneumoniae and mediates adhesion to host epithelial cellsQ80178422
Borrelia burgdorferi erp genes are expressed at different levels within tissues of chronically infected mammalian hostsQ82790566
The C-terminus of complement regulator Factor H mediates target recognition: evidence for a compact conformation of the native proteinQ83193267
Human complement factor H: an additional gene product of 43 kDa isolated from human plasma shows cofactor activity for the cleavage of the third component of complementQ93521635
Lyme borreliosisQ94329194
Molecular modelling of the C-terminal domains of factor H of human complement: a correlation between haemolytic uraemic syndrome and a predicted heparin binding siteQ33341100
Factor H family proteins: on complement, microbes and human diseasesQ33345389
Factor H binds to washed human platelets.Q33364421
FHL-1/reconectin: a human complement and immune regulator with cell-adhesive functionQ33594106
Molecular evidence for a new bacteriophage of Borrelia burgdorferiQ33636694
Serum complement sensitivity as a key factor in Lyme disease ecology.Q33751851
DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodiesQ33767776
Characterization of Borrelia burgdorferi BlyA and BlyB proteins: a prophage-encoded holin-like systemQ33792535
A second allele of eppA in Borrelia burgdorferi strain B31 is located on the previously undetected circular plasmid cp9-2Q33994874
Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptidesQ34000754
Molecular and evolutionary characterization of the cp32/18 family of supercoiled plasmids in Borrelia burgdorferi 297.Q34003671
Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borrelia burgdorferi strain 297 by mammalian host-specific signalsQ34007612
Complement evasion by Borrelia burgdorferi: serum-resistant strains promote C3b inactivation.Q34007675
Demonstration of the genetic stability and temporal expression of select members of the lyme disease spirochete OspF protein family during infection in miceQ34008518
Transduction by phiBB-1, a bacteriophage of Borrelia burgdorferiQ34011472
Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferiQ34125855
Simultaneous coexpression of Borrelia burgdorferi Erp proteins occurs through a specific, erp locus-directed regulatory mechanismQ34316819
Borrelia burgdorferi genes selectively expressed in the infected hostQ34317419
Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein.Q34416754
Host association of Borrelia burgdorferi sensu lato--the key role of host complementQ34517623
Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteinsQ34633017
Borrelia burgdorferi EbfC, a novel, chromosomally encoded protein, binds specific DNA sequences adjacent to erp loci on the spirochete's resident cp32 prophagesQ34697421
Immune evasion of Borrelia burgdorferi: insufficient killing of the pathogens by complement and antibodyQ34761880
Temporal analysis of Borrelia burgdorferi Erp protein expression throughout the mammal-tick infectious cycleQ34945715
Complement regulator-acquiring surface proteins of Borrelia burgdorferi: a new protein family involved in complement resistanceQ34992345
Comprehensive analysis of the factor h binding capabilities of borrelia species associated with lyme disease: delineation of two distinct classes of factor h binding proteinsQ35012230
Linear and circular plasmid content in Borrelia burgdorferi clinical isolatesQ35105597
Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferiQ35452406
Circular and linear plasmids of Lyme disease spirochetes have extensive homology: characterization of a repeated DNA elementQ35605518
Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene familyQ35608119
A family of genes located on four separate 32-kilobase circular plasmids in Borrelia burgdorferi B31.Q35608499
Molecular and evolutionary analyses of a variable series of genes in Borrelia burgdorferi that are related to ospE and ospF, constitute a gene family, and share a common upstream homology box.Q35613858
Homology throughout the multiple 32-kilobase circular plasmids present in Lyme disease spirochetes.Q35618631
Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmidsQ35625493
Molecular adaptation of Borrelia burgdorferi in the murine hostQ36370802
Hematogenous dissemination in early Lyme diseaseQ36679473
Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologueQ36812377
Borrelia burgdorferi contains repeated DNA sequences that are species specific and plasmid associatedQ36978937
The C-terminus of complement factor H is essential for host cell protectionQ37238656
Temporal pattern of Borrelia burgdorferi p21 expression in ticks and the mammalian hostQ37364561
Molecular characterization of Borrelia burgdorferi erp promoter/operator elementsQ37425648
Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding siteQ38596477
FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulatedQ39012605
The human complement regulatory factor-H-like protein 1, which represents a truncated form of factor H, displays cell-attachment activityQ39063137
Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferiQ39523100
Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in miceQ39755087
Adherence of Borrelia burgdorferi to the proteoglycan decorinQ39822919
Complement-mediated serum sensitivity among spirochetes that cause Lyme disease.Q39829393
Demonstration of cotranscription and 1-methyl-3-nitroso-nitroguanidine induction of a 30-gene operon of Borrelia burgdorferi: evidence that the 32-kilobase circular plasmids are prophagesQ39892227
Demonstration of the involvement of outer surface protein E coiled coil structural domains and higher order structural elements in the binding of infection-induced antibody and the complement-regulatory protein, factor H.Q40519476
The C-terminus of factor H: monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteinsQ41044029
Characterization of factor H binding to human polymorphonuclear leukocytes.Q41514083
Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia afzelii and Borrelia gariniiQ41818115
Selective binding of Borrelia burgdorferi OspE paralogs to factor H and serum proteins from diverse animals: possible expansion of the role of OspE in Lyme disease pathogenesis.Q41902649
Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animalsQ42112517
Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferiQ42665527
Sigma factor selectivity in Borrelia burgdorferi: RpoS recognition of the ospE/ospF/elp promoters is dependent on the sequence of the -10 regionQ43579069
Binding of human complement regulators FHL-1 and factor H to CRASP-1 orthologs of Borrelia burgdorferiQ44782441
Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H.Q44885071
Immunological characterization of the complement regulator factor H-binding CRASP and Erp proteins of Borrelia burgdorferi.Q47595731
Evidence of past recombination events among the genes encoding the Erp antigens of Borrelia burgdorferiQ47721027
Fibronectin-binding activity in Borrelia burgdorferi1.Q47760192
Identification of a 47 kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31.Q47988454
Intra- and interbacterial genetic exchange of Lyme disease spirochete erp genes generates sequence identity amidst diversityQ48219438
Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp ProteinsQ48220868
Detection of Borrelia burgdorferi gene expression during mammalian infection using transcriptional fusions that produce green fluorescent protein.Q50729216
Analysis of Borrelia burgdorferi gene expression during life cycle phases of the tick vector Ixodes scapularis.Q52591505
Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs.Q53958156
Comparison of two laboratory methods for the determination of serum resistance in Borrelia burgdorferi isolates.Q54054345
Complement-mediated killing of the Lyme disease spirochete Borrelia burgdorferi. Role of antibody in formation of an effective membrane attack complex.Q54294834
Expression of Borrelia burgdorferi erp genes during infection of non-human primates.Q54658273
Infectivity of Borrelia burgdorferi relative to route of inoculation and genotype in laboratory miceQ68184193
Demonstration of spirochaetes in patients with Lyme disease with a modified silver stainQ68994291
P407language of work or nameEnglishQ1860
P921main subjectLyme diseaseQ201989
P304page(s)257-267
P577publication date2008-01-11
P1433published inInternational Journal of Medical MicrobiologyQ6051476
P1476titleLyme borreliosis spirochete Erp proteins, their known host ligands, and potential roles in mammalian infection
P478volume298 Suppl 1

Reverse relations

cites work (P2860)
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