| scholarly article | Q13442814 |
| P50 | author | Greg N. Fuller | Q37370656 |
| Chantal Reina-Ortiz | Q81774000 | ||
| Nobuyoshi Hiraoka | Q88037815 | ||
| P2093 | author name string | Wei Qiao | |
| Raymond Sawaya | |||
| Waldemar Priebe | |||
| Jun Wei | |||
| Amy B Heimberger | |||
| Ling-Yuan Kong | |||
| David S Yang | |||
| Mohamed Abou-Ghazal | |||
| P2860 | cites work | Activation of JAK-STAT pathway is required for platelet-derived growth factor-induced proliferation of pancreatic stellate cells | Q28569527 |
| Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival | Q29547865 | ||
| The STATs of cancer--new molecular targets come of age | Q29614601 | ||
| Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity | Q33282964 | ||
| IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways | Q33888307 | ||
| IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation. | Q33892268 | ||
| Evaluation of survival data and two new rank order statistics arising in its consideration | Q34054360 | ||
| Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice | Q34185116 | ||
| Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer | Q34210036 | ||
| Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth | Q34922227 | ||
| Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors | Q35589063 | ||
| STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation | Q35770784 | ||
| Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma | Q35954415 | ||
| A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo | Q36647747 | ||
| Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. | Q36691086 | ||
| Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications | Q36749049 | ||
| Stat3 as a potential target for cancer immunotherapy. | Q36807448 | ||
| A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells | Q36973832 | ||
| Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis | Q37486563 | ||
| Loss of the AP-2alpha transcription factor is associated with the grade of human gliomas. | Q38331388 | ||
| Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential | Q38333986 | ||
| Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma | Q38350139 | ||
| Shaping gene expression in activated and resting primary macrophages by IL-10. | Q38363550 | ||
| Expression of activated signal transducer and activator of transcription 3 predicts expression of vascular endothelial growth factor in and angiogenic phenotype of human gastric cancer | Q38443694 | ||
| Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity | Q40351340 | ||
| Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas | Q40617323 | ||
| Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma. | Q40724591 | ||
| The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses | Q41779891 | ||
| IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo | Q42139164 | ||
| Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma. | Q43782950 | ||
| Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. | Q44021327 | ||
| Cytochrome P450 1B1 expression in glial cell tumors: an immunotherapeutic target | Q44093314 | ||
| Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas | Q44927492 | ||
| The role of p-STAT3 (ser727) revealed by its association with Ki-67 in cervical intraepithelial neoplasia | Q46591719 | ||
| Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer | Q46831080 | ||
| Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke. | Q47349753 | ||
| Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma | Q47672876 | ||
| Immune cell infiltration of intrinsic and metastatic intracranial tumours. | Q47966453 | ||
| Relationship of lymphocyte invasion and survival of brain tumor patients | Q48162265 | ||
| Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival | Q48347764 | ||
| Activation of stat3 in human melanoma promotes brain metastasis | Q48616814 | ||
| Mononuclear lymphoid populations infiltrating the microenvironment of primary CNS tumors. Characterization of cell subsets with monoclonal antibodies | Q48664792 | ||
| Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas. | Q48973528 | ||
| STAT3 activation in macrophages following infection with Salmonella | Q50096961 | ||
| Activation state EGFR and STAT-3 as prognostic markers in resected non-small cell lung cancer. | Q51773934 | ||
| Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions | Q51803685 | ||
| Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection | Q53332082 | ||
| In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy | Q53362509 | ||
| FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis | Q53572147 | ||
| Stat3 expression in oral squamous cell carcinoma: association with clinicopathological parameters and survival | Q53596023 | ||
| A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. | Q55467677 | ||
| Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients. | Q55471514 | ||
| Central endotoxin induces different patterns of interleukin (IL)-1 beta and IL-6 messenger ribonucleic acid expression and IL-6 secretion in the brain and periphery | Q72572323 | ||
| Astrocytes produce and release interleukin-1, interleukin-6, tumor necrosis factor alpha and interferon-gamma following traumatic and metabolic injury | Q73706122 | ||
| Activation of signal transducer and activator of transcription 3 in renal cell carcinoma: a study of incidence and its association with pathological features and clinical outcome | Q74493305 | ||
| [Effects of STAT3 antisense oligodeoxynucleotides on apoptosis and proliferation of mouse melanoma cell line B16] | Q82824486 | ||
| Tumor-infiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma | Q83895049 | ||
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| inflammation | Q101991 | ||
| P304 | page(s) | 8228-8235 | |
| P577 | publication date | 2008-12-01 | |
| P1433 | published in | Clinical Cancer Research | Q332253 |
| P1476 | title | The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas | |
| P478 | volume | 14 |
| Q58614591 | A Prognostic Signature for Lower Grade Gliomas Based on Expression of Long Non-Coding RNAs |
| Q64087577 | A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma |
| Q33597235 | A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis |
| Q48318477 | Activation of JAK/STAT signal pathway predicts poor prognosis of patients with gliomas |
| Q35230410 | Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251 |
| Q33578030 | Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM |
| Q48645834 | Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells |
| Q38779789 | CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis |
| Q33907955 | Celecoxib suppresses the phosphorylation of STAT3 protein and can enhance the radiosensitivity of medulloblastoma-derived cancer stem-like cells |
| Q37640613 | Challenges in clinical design of immunotherapy trials for malignant glioma |
| Q24632103 | Consensus on the role of human cytomegalovirus in glioblastoma |
| Q39449408 | Current Advances in Checkpoint Inhibitors: Lessons from Non-Central Nervous System Cancers and Potential for Glioblastoma |
| Q33669979 | Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes |
| Q48679476 | Downregulation of PCDH9 predicts prognosis for patients with glioma |
| Q24338526 | EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma |
| Q30456087 | EGFR-targeted therapy in malignant glioma: novel aspects and mechanisms of drug resistance |
| Q34343768 | Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma. |
| Q38953017 | Embracing rejection: Immunologic trends in brain metastasis |
| Q88461678 | Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi |
| Q91635356 | Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment |
| Q35674906 | FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells |
| Q52720206 | GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway |
| Q38198930 | Genetic Interactions of STAT3 and Anticancer Drug Development |
| Q34129168 | Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway |
| Q34992518 | Glioma cancer stem cells induce immunosuppressive macrophages/microglia |
| Q24631473 | Glioma-Associated Cytomegalovirus Mediates Subversion of the Monocyte Lineage to a Tumor Propagating Phenotype |
| Q37435455 | Immune heterogeneity of glioblastoma subtypes: extrapolation from the cancer genome atlas |
| Q34676437 | Immune therapeutic targeting of glioma cancer stem cells |
| Q41541275 | Immunoexcitatory mechanisms in glioma proliferation, invasion and occasional metastasis |
| Q36224048 | Immunosuppressive mechanisms in glioblastoma |
| Q27002510 | Immunotherapy for primary brain tumors: no longer a matter of privilege |
| Q28078539 | Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites? |
| Q39283602 | Importance of direct macrophage-tumor cell interaction on progression of human glioma. |
| Q64928237 | Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations. |
| Q43940962 | Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway |
| Q37967667 | Inflammation: what role in pediatric cancer? |
| Q51579247 | Inhibition of STAT3 enhances the radiosensitizing effect of temozolomide in glioblastoma cells in vitro and in vivo |
| Q84365414 | Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3 |
| Q36132647 | Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma |
| Q38051761 | Interleukins in glioblastoma pathophysiology: implications for therapy. |
| Q34393758 | Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses |
| Q34462874 | Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition |
| Q50894719 | MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma |
| Q38194054 | Microenvironmental clues for glioma immunotherapy |
| Q36862759 | Modulating antiangiogenic resistance by inhibiting the signal transducer and activator of transcription 3 pathway in glioblastoma |
| Q35587235 | Molecular heterogeneity in a patient-derived glioblastoma xenoline is regulated by different cancer stem cell populations |
| Q37457873 | NF-kappaB and STAT3 signaling in glioma: targets for future therapies |
| Q100407742 | Noncanonical pS727 post translational modification dictates major STAT3 activation and downstream functions in breast cancer |
| Q55363685 | Nuclear Smad6 promotes gliomagenesis by negatively regulating PIAS3-mediated STAT3 inhibition. |
| Q37301799 | Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma |
| Q34536056 | Nuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosis |
| Q36493843 | PD-L1 expression and prognostic impact in glioblastoma |
| Q34457728 | Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth |
| Q53087536 | Phospho-flow detection of constitutive and cytokine-induced pSTAT3/5, pAKT and pERK expression highlights novel prognostic biomarkers for patients with multiple myeloma |
| Q38621047 | Pilot Study of Whole Blood MicroRNAs as Potential Tools for Diffuse Low-Grade Gliomas Detection |
| Q33603599 | Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy |
| Q37078999 | Prioritization schema for immunotherapy clinical trials in glioblastoma |
| Q37190200 | Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis |
| Q49154036 | Prognostic significance of IL-8-STAT-3 pathway in astrocytomas: Correlation with IL-6, VEGF and microvessel morphometry |
| Q38199935 | Reciprocal Supportive Interplay between Glioblastoma and Tumor-Associated Macrophages |
| Q38232852 | Resistance to antiangiogenic therapies |
| Q38962315 | Role of STAT3 in Genesis and Progression of Human Malignant Gliomas. |
| Q36351195 | STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3 |
| Q38671957 | STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications |
| Q38903930 | STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma. |
| Q38205362 | STAT3 Target Genes Relevant to Human Cancers |
| Q55461070 | STAT3 Tyr705 phosphorylation affects clinical outcome in patients with newly diagnosed supratentorial glioblastoma. |
| Q54427862 | STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy? |
| Q37702595 | STAT3 overexpression promotes metastasis in intrahepatic cholangiocarcinoma and correlates negatively with surgical outcome |
| Q58716603 | STAT3 promotes tumour progression in glioma by inducing FOXP1 transcription |
| Q34177244 | Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model. |
| Q33910722 | Signal transducer and activator of transcription 3 (STAT3) promoter methylation and expression in pituitary adenoma |
| Q36179166 | Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma |
| Q101563903 | Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy |
| Q52625023 | T-Cell Dysfunction in Glioblastoma: Applying a New Framework. |
| Q35987091 | The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival |
| Q47247953 | The biology and therapeutic management of melanoma brain metastases |
| Q38053272 | The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment |
| Q39420094 | The efficiency of silencing expression of the gene coding STAT3 transcriptional factor and susceptibility of bladder cancer cells to apoptosis. |
| Q36895415 | The role of JAK-STAT signaling within the CNS. |
| Q38363102 | The role of STAT3 in tumor-mediated immune suppression |
| Q91707540 | The role of interleukin-6-STAT3 signalling in glioblastoma |
| Q38540262 | The role of regulatory T cells and microglia in glioblastoma-associated immunosuppression |
| Q39521993 | The therapeutic potential of inhibitors of the signal transducer and activator of transcription 3 for central nervous system malignancies |
| Q90173116 | Tumor Development and Angiogenesis in Adult Brain Tumor: Glioblastoma |
| Q47826206 | When Immune Cells Turn Bad-Tumor-Associated Microglia/Macrophages in Glioma. |
| Q37191655 | miR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma |
| Q37276897 | miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis |
| Q37420546 | yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients. |
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