Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis.

scientific article published on 24 February 2016

Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.7690
P932PMC publication ID4924641
P698PubMed publication ID26934440

P50authorFrancis RodierQ58885077
P2093author name stringInés Colmegna
Dominique Shum-Tim
Stéphanie Nadeau
Felipe Apablaza
Reggie Hamdy
Audrey Carrier-Leclerc
Kelsey O'Hagan-Wong
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Insulin-like growth factor binding proteins-2 and -4 enhance the migration of human CD34-/CD133+ hematopoietic stem and progenitor cells.Q30318835
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Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppressionQ35930081
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Interleukin-6 induces the lineage commitment of bone marrow-derived mesenchymal multipotent cells through down-regulation of Sox2 by osteogenic transcription factorsQ47890725
Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments.Q53184654
Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes.Q54348216
Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftmentQ58379782
Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell functionQ83344193
Age-related changes in human hematopoietic stem/progenitor cellsQ83648455
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)13285-13296
P577publication date2016-03-01
P1433published inOncotargetQ1573155
P1476titleIncreased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis
P478volume7

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cites work (P2860)
Q38962768A Proinflammatory Secretome Mediates the Impaired Immunopotency of Human Mesenchymal Stromal Cells in Elderly Patients with Atherosclerosis
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