Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments.

scientific article published on 20 March 2012

Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3109/09553002.2012.666001
P698PubMed publication ID22348537
P5875ResearchGate publication ID221845920

P50authorMartina ŘezáčováQ43121076
Stanislav FilipQ43121083
Jakub SuchánekQ82432907
Benjamin VisekQ96134439
Darina MuthnaQ114421858
Jana ČmielováQ114421859
Lenka BruckovaQ114421860
Radim HavelekQ43121059
Jaroslav MokrýQ43121070
P2093author name stringDenis English
Tomas Soukup
Jirina Vavrova
Alena Jiroutová
P2860cites workProtocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivoQ43221614
Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and -independent mechanismsQ44684697
Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.Q45859658
Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser780 and Ser795 is mediated by ERK1/2 in small intestine epithelial cellsQ46673526
Interstitial chromatin alteration causes persistent p53 activation involved in the radiation-induced senescence-like growth arrestQ46855548
Investigation of multipotent postnatal stem cells from human periodontal ligament.Q47217465
Isolation and characterization of multipotent human periodontal ligament stem cellsQ50466869
Ionizing radiation of mesenchymal stem cells results in diminution of the precursor pool and limits potential for multilineage differentiation.Q53468754
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53Q24311891
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociationQ28206029
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2Q28254119
Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplicationQ28611456
Cellular senescence: when bad things happen to good cellsQ29615561
Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivoQ29618057
Survival responses of human embryonic stem cells to DNA damageQ34078474
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytesQ34106524
Radiation-induced cell death mechanismsQ34116777
Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiationQ34946238
Oral sequelae of head and neck radiotherapy.Q35150817
Hallmarks of senescence in carcinogenesis and cancer therapyQ35743144
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cellsQ35924505
Mesenchymal stem cells: cell biology and potential use in therapy.Q35951877
ATM signaling and genomic stability in response to DNA damageQ35986624
The signals and pathways activating cellular senescenceQ36060167
The role of DNA damage repair in aging of adult stem cellsQ37045395
Stress-induced premature senescence (SIPS)--influence of SIPS on radiotherapyQ37064796
Comparison of human dental pulp and bone marrow stromal stem cells by cDNA microarray analysisQ38294332
Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transitionQ39631415
Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteins.Q39912482
The sensitivity of human mesenchymal stem cells to ionizing radiationQ40256057
p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cellsQ40347642
Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shorteningQ40836730
Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damageQ42635438
Irradiation of adult human dental pulp stem cells provokes activation of p53, cell cycle arrest, and senescence but not apoptosis.Q43121021
P433issue5
P304page(s)393-404
P577publication date2012-03-20
P1433published inInternational Journal of Radiation BiologyQ2093427
P1476titleGamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments
P478volume88

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cites work (P2860)
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