Telomerase Does Not Improve DNA Repair in Mitochondria upon Stress but Increases MnSOD Protein under Serum-Free Conditions

scientific article published on 19 December 2019

Telomerase Does Not Improve DNA Repair in Mitochondria upon Stress but Increases MnSOD Protein under Serum-Free Conditions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS21010027
P932PMC publication ID6981674
P698PubMed publication ID31861522

P50authorOlasubomi AkintolaQ92154135
P2093author name stringGabriele Saretzki
Bianca Schmid
Alexander Martens
P2860cites workForkhead transcription factor FOXO3a protects quiescent cells from oxidative stressQ29619436
Expression of (NES-)hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stressQ33593132
Arsenicals affect base excision repair by several mechanismsQ34202939
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosisQ34551106
The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.Q35020283
Extra-telomeric functions of human telomerase: cancer, mitochondria and oxidative stress.Q38224271
Mitochondrial genetic abnormalities after radiation exposureQ39004517
Effects of X-irradiation on mitochondrial DNA damage and its supercoiling formation changeQ39491576
Immediate and gradual gene expression changes in telomerase over-expressing fibroblastsQ39679274
A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunctionQ39749949
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.Q39787838
Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts.Q40451759
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.Q40487014
Accumulation of the common mitochondrial DNA deletion induced by ionizing radiationQ40530947
Arsenic induces oxidative DNA damage in mammalian cellsQ40713090
Induction of a particular deletion in mitochondrial DNA by X rays depends on the inherent radiosensitivity of the cellsQ41085843
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damageQ42450430
hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer CellsQ42479814
Irradiation of adult human dental pulp stem cells provokes activation of p53, cell cycle arrest, and senescence but not apoptosis.Q43121021
Mitochondrial damage mediates genotoxicity of arsenic in mammalian cellsQ46440305
Tests of the single-hit DNA damage model.Q51811542
Rejoining of DNA strand breaks by T4 DNA ligase in mammalian cells.Q51843647
Gene-specific repair of gamma-ray-induced DNA strand breaks in colon cancer cells: no coupling to transcription and no removal from the mitochondrial genome.Q52919892
Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments.Q53184654
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stressQ60284577
Inhibition of DNA ligase activity by arsenite: a possible mechanism of its comutagenesisQ69431597
Molecular damage induced directly and indirectly by ionizing radiation in DNAQ72864872
Nuclear and mitochondrial genome instability in human breast cancerQ74181156
hTERT associates with human telomeres and enhances genomic stability and DNA repairQ78794137
Mechanisms of Mitochondrial DNA Repair in MammalsQ88293800
FOXO3a from the Nucleus to the Mitochondria: A Round Trip in Cellular Stress ResponseQ90226885
Mitochondrial Antioxidants and the Maintenance of Cellular Hydrogen Peroxide LevelsQ90600301
Enzymology of mitochondrial DNA repairQ90807481
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P577publication date2019-12-19
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleTelomerase Does Not Improve DNA Repair in Mitochondria upon Stress but Increases MnSOD Protein under Serum-Free Conditions
P478volume21

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