RACK1 interacts with filamin-A to regulate plasma membrane levels of the cystic fibrosis transmembrane conductance regulator.

scientific article published on May 2013

RACK1 interacts with filamin-A to regulate plasma membrane levels of the cystic fibrosis transmembrane conductance regulator. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00026.2013
P932PMC publication ID3725521
P698PubMed publication ID23636454
P5875ResearchGate publication ID236602897

P50authorSaurav MisraQ57421650
Richard C PageQ59095929
P2093author name stringLaura Smith
Ekta Kohli
Carole M Liedtke
Joseph Amick
Paul Litman
P2860cites workModulation of dopamine D(2) receptor signaling by actin-binding protein (ABP-280)Q22253247
NIH Image to ImageJ: 25 years of image analysisQ23319322
The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1Q24291061
FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodellingQ24297925
Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptorQ24307465
Migfilin, a molecular switch in regulation of integrin activationQ24328844
The ABC protein turned chloride channel whose failure causes cystic fibrosisQ24657572
Cystic fibrosisQ24680357
Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin bindingQ27650823
Structure of a signal transduction regulator, RACK1, fromArabidopsis thalianaQ27651721
Direct Link between RACK1 Function and Localization at the Ribosome In VivoQ27653299
Biochemical Basis of the Interaction between Cystic Fibrosis Transmembrane Conductance Regulator and Immunoglobulin-like Repeats of FilaminQ27660360
Structure of human Rack1 protein at a resolution of 2.45 ÅQ27671222
A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and functionQ28115628
The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membraneQ28138284
Identification of a surface on the beta-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5Q28214056
Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane regulator involves binding to a receptor for activated C kinase (RACK1) and RACK1 binding to Na+/H+ exchange regulatory factorQ28214893
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1Q28219213
ImageJ for microscopyQ28253317
An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeletonQ28277503
The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alphaQ28585908
A guided tour into subcellular colocalization analysis in light microscopyQ29547199
Automatic and quantitative measurement of protein-protein colocalization in live cells.Q29616276
C2-domains, structure and function of a universal Ca2+-binding domainQ29619459
Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactionsQ30478396
Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopyQ31042736
Cystic fibrosis: exploiting its genetic basis in the hunt for new therapiesQ33664918
Cystic fibrosis transmembrane conductance regulator interacts with multiple immunoglobulin domains of filamin A.Q33883521
Phosphorylation of CFTR by PKA promotes binding of the regulatory domainQ33910924
A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKAQ34468233
The RACK1 scaffold protein: a dynamic cog in cell response mechanismsQ34999716
Adapter protein SH2B1beta binds filamin A to regulate prolactin-dependent cytoskeletal reorganization and cell motilityQ35073608
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulatorQ35123086
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR.Q35576178
Submucosal glands and airway defenseQ36236757
RACK1 has the nerve to act: structure meets function in the nervous system.Q36386609
Filamins: promiscuous organizers of the cytoskeletonQ36510058
CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosisQ36512937
CFTR function and prospects for therapyQ37096095
Phosphorylation facilitates the integrin binding of filamin under forceQ37475550
Filamins in cell signaling, transcription and organ developmentQ37671360
Structural Portrait of Filamin Interaction MechanismsQ37795851
In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimerQ38774272
A novel association between filamin A and NF-κB inducing kinase couples CD28 to inhibitor of NF-κB kinase α and NF-κB activationQ39600959
Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon.Q39737159
PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR.Q39938645
Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cellsQ40056704
Role of the scaffold protein RACK1 in apical expression of CFTR.Q40149608
The N-terminus of the WD5 repeat of human RACK1 binds to airway epithelial NHERF1.Q40241406
Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibroQ40366116
Role of a PDZ1 domain of NHERF1 in the binding of airway epithelial RACK1 to NHERF1.Q40568394
Molecular assembly of cystic fibrosis transmembrane conductance regulator in plasma membraneQ40570817
Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2.Q40908999
Antisense oligonucleotide to PKC-epsilon alters cAMP-dependent stimulation of CFTR in Calu-3 cellsQ40994945
The role of actin-binding protein 280 in integrin-dependent mechanoprotectionQ41069999
RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitroQ41697377
Structural basis for vertebrate filamin dimerizationQ41792396
Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.Q44317051
A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.Q47717695
Potentiation of effect of PKA stimulation of Xenopus CFTR by activation of PKC: role of NBD2.Q50672698
Phosphorylated filamin A regulates actin-linked caveolae dynamics.Q50675024
Filamin A is required for T cell activation mediated by protein kinase C-theta.Q53610750
New insights into cystic fibrosis: molecular switches that regulate CFTRQ56680230
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcystic fibrosisQ178194
transmembrane proteinQ424204
P304page(s)C111-20
P577publication date2013-05-01
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleRACK1 interacts with filamin-A to regulate plasma membrane levels of the cystic fibrosis transmembrane conductance regulator
P478volume305

Reverse relations

cites work (P2860)
Q36389271Oligopeptide Competition Assay for Phosphorylation Site Determination
Q55129594Trafficking, localization and degradation of the Na+,HCO3- co-transporter NBCn1 in kidney and breast epithelial cells.

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