Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions

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Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions is …
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scholarly articleQ13442814

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P356DOI10.1091/MBC.E06-08-0670
P932PMC publication ID1679663
P698PubMed publication ID16987954
P5875ResearchGate publication ID6806379

P50authorGergely L LukacsQ38322272
P2093author name stringA S Verkman
Peter M Haggie
Jung Kyung Kim
P2860cites workA Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expressionQ24291900
A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactionsQ24311225
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteinsQ24316901
Quantum dots for live cells, in vivo imaging, and diagnosticsQ24532049
Rapid hop diffusion of a G-protein-coupled receptor in the plasma membrane as revealed by single-molecule techniquesQ24538587
Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinaseQ24617464
Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchangerQ24629554
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomesQ24676764
Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrinQ28118810
The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membraneQ28138284
Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activityQ28142263
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptorQ28145098
Assembly and Trafficking of a Multiprotein ROMK (Kir 1.1) Channel Complex by PDZ InteractionsQ28182435
Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane regulator involves binding to a receptor for activated C kinase (RACK1) and RACK1 binding to Na+/H+ exchange regulatory factorQ28214893
Regulation of CFTR chloride channels by syntaxin and Munc18 isoformsQ28255553
Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)Q28272686
An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeletonQ28277503
Paradigm Shift of the Plasma Membrane Concept from the Two-Dimensional Continuum Fluid to the Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane MoleculesQ29011044
ERM proteins and merlin: integrators at the cell cortexQ29619893
Membrane lateral diffusion and capture of CFTR within transient confinement zones.Q30477935
Increased diffusional mobility of CFTR at the plasma membrane after deletion of its C-terminal PDZ binding motifQ33195731
A PDZ-interacting domain in CFTR is an apical membrane polarization signalQ33902133
E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cellsQ33909378
Single-particle tracking: the distribution of diffusion coefficientsQ33915302
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.Q33925348
Diffusion dynamics of glycine receptors revealed by single-quantum dot trackingQ34270675
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacyQ34336290
A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKAQ34468233
Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interactionQ34662162
Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epitheliaQ34762614
The role of receptor diffusion in the organization of the postsynaptic membraneQ35097310
The role of regulated CFTR trafficking in epithelial secretionQ35141221
Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partnersQ36151796
COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartmentsQ36326371
The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A.Q40359721
Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7.Q40635663
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epitheliaQ40662051
PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulatorQ40712140
Phospholipids undergo hop diffusion in compartmentalized cell membraneQ40726143
Receptor activation and homer differentially control the lateral mobility of metabotropic glutamate receptor 5 in the neuronal membrane.Q40730633
PKA holoenzyme is functionally coupled to CFTR by AKAPsQ40901386
Butyrate increases apical membrane CFTR but reduces chloride secretion in MDCK cellsQ40935945
C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutationQ40939810
Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity.Q42825535
Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors.Q44945678
Effects of growth surface on differentiation of cultures of human tracheal epitheliumQ46118016
New insights into cystic fibrosis: molecular switches that regulate CFTRQ56680230
Association of cystic fibrosis transmembrane conductance regulator and protein phosphatase 2CQ73041185
Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signalQ77912061
P4510describes a project that usesImageJQ1659584
P433issue12
P921main subjectquantum dotQ1133068
quantum biologyQ1429339
P1104number of pages9
P304page(s)4937-4945
P577publication date2006-09-20
P1433published inMolecular Biology of the CellQ2338259
P1476titleTracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions
P478volume17

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cites work (P2860)
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