scholarly article | Q13442814 |
P356 | DOI | 10.1152/AJPRENAL.00652.2012 |
P8608 | Fatcat ID | release_tzqcjdyxoraczddnhojw6xh7aa |
P932 | PMC publication ID | 3725674 |
P698 | PubMed publication ID | 23594824 |
P5875 | ResearchGate publication ID | 236224130 |
P50 | author | Douglas C Eaton | Q40752420 |
P2093 | author name string | Ling Yu | |
Abdel A Alli | |||
Hui Cai | |||
Hui-Fang Bao | |||
Otor Al-Khalili | |||
Qian Yue | |||
DeXuan Wang | |||
P2860 | cites work | Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression | Q24534668 |
Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members | Q24633684 | ||
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway | Q24648927 | ||
Characterization of the kinase activity of a WNK4 protein complex | Q24658170 | ||
An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis | Q24669948 | ||
Intersectin links WNK kinases to endocytosis of ROMK1 | Q24680263 | ||
Human hypertension caused by mutations in WNK kinases | Q28212182 | ||
Characterisation of a human acid-sensing ion channel (hASIC1a) endogenously expressed in HEK293 cells | Q28213635 | ||
Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel | Q28240272 | ||
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits | Q28249570 | ||
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome | Q28288744 | ||
Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels | Q28572912 | ||
WNK kinases regulate thiazide-sensitive Na-Cl cotransport | Q28584824 | ||
Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone. | Q33868725 | ||
WNK1 activates SGK1 to regulate the epithelial sodium channel. | Q33900653 | ||
RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter | Q34085234 | ||
Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathways | Q34155287 | ||
Internalization of UT-A1 urea transporter is dynamin dependent and mediated by both caveolae- and clathrin-coated pit pathways | Q34426294 | ||
WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells | Q34524228 | ||
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. | Q34711250 | ||
WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism. | Q35159554 | ||
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo. | Q35651892 | ||
WNK kinases: molecular regulators of integrated epithelial ion transport | Q35858400 | ||
Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process | Q35974133 | ||
Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch | Q36088720 | ||
Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool | Q36412575 | ||
Recycling of proteins between the endoplasmic reticulum and Golgi complex | Q36457800 | ||
Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel | Q36749273 | ||
Multigene kinase network, kidney transport, and salt in essential hypertension | Q36862737 | ||
Regulation of the epithelial sodium channel by phosphatidylinositides: experiments, implications, and speculations | Q36866990 | ||
Regulation of a third conserved phosphorylation site in SGK1 | Q37081895 | ||
Physiologic regulation of the epithelial sodium channel by phosphatidylinositides | Q37241597 | ||
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction | Q37258483 | ||
Mechanisms of Type I and Type II Pseudohypoaldosteronism | Q37786859 | ||
Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger | Q39318132 | ||
The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool | Q40112756 | ||
Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC. | Q40133019 | ||
Spontaneous autocrine release of protons activates ASIC-mediated currents in HEK293 cells | Q40143880 | ||
Effect of divalent heavy metals on epithelial Na+ channels in A6 cells | Q40146587 | ||
Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells | Q40441541 | ||
Distinct pools of epithelial sodium channels are expressed at the plasma membrane | Q40507820 | ||
Epithelial sodium channels are activated by furin-dependent proteolysis | Q40581030 | ||
Carboxylmethylation of the beta subunit of xENaC regulates channel activity | Q41000456 | ||
Brefeldin A inhibition of apical Na+ channels in epithelia | Q41250182 | ||
Epithelial sodium channels: function, structure, and regulation | Q41441322 | ||
Differential effects of brefeldin A on hormonally regulated Na+ transport in a model renal epithelial cell line | Q41480049 | ||
Effects of vasopressin and cAMP on single amiloride-blockable Na channels | Q41685903 | ||
Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation | Q41889980 | ||
Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4. | Q42479166 | ||
Beta-adrenergic regulation of amiloride-sensitive lung sodium channels | Q43906827 | ||
Na+/H+ exchanger activity in the pig kidney epithelial cell line, LLC-PK1: inhibition by amiloride and its derivatives | Q45275475 | ||
Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure | Q46146557 | ||
Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. | Q46897768 | ||
Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition | Q48792396 | ||
Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface | Q48925095 | ||
Heteromeric assembly of acid-sensitive ion channel and epithelial sodium channel subunits. | Q51796309 | ||
Reconstituted amiloride-inhibited sodium transporter from rabbit kidney medulla is responsible for Na+-H+ exchange | Q70189773 | ||
Mineralocorticoid regulation of epithelial Na+ channels is maintained in a mouse model of Liddle's syndrome | Q73234623 | ||
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule | Q80238253 | ||
P433 | issue | 1 | |
P921 | main subject | protein ubiquitination | Q3547638 |
P304 | page(s) | F31-41 | |
P577 | publication date | 2013-04-17 | |
P1433 | published in | American Journal of Physiology - Renal Physiology | Q2610177 |
P1476 | title | WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination | |
P478 | volume | 305 |
Q37260675 | Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7). |
Q49911717 | Aldosterone, SGK1, and ion channels in the kidney. |
Q51102148 | Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC. |
Q36017597 | Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane |
Q38307745 | Dietary potassium and the renal control of salt balance and blood pressure |
Q38987679 | Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion |
Q34276479 | ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice |
Q37575563 | ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice |
Q51076939 | ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4PHAII mice. |
Q39415845 | Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport. |
Q39155176 | Regulation of Transporters and Channels by Membrane-Trafficking Complexes in Epithelial Cells |
Q26770258 | Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity |
Q38230038 | The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters |
Q61811751 | Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection |
Q37694287 | WNK signalling pathways in blood pressure regulation |
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