Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members

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Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.103432
P3181OpenCitations bibliographic resource ID3921098
P932PMC publication ID2919078
P698PubMed publication ID20525693

P50authorMelanie H. CobbQ38327784
P2093author name stringBing-e Xu
Yingming Zhao
Yu-Chi Juang
Chou-Long Huang
Steve Stippec
Seung-Kuy Cha
Chih-Jen Cheng
Yingda Xu
Samarpita Sengupta
Svetlana Earnest
Charles J Heise
Staci L Deaton
P2860cites workSLC26A9 is a Cl(-) channel regulated by the WNK kinasesQ24336113
WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrateQ24530650
Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoformsQ24537454
Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4Q24541348
Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoformQ24633475
WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cellsQ24676697
PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)Q28116210
WNK kinases, a novel protein kinase subfamily in multi-cellular organismsQ28188729
Regulation of WNK1 by an autoinhibitory domain and autophosphorylationQ28206619
Human hypertension caused by mutations in WNK kinasesQ28212182
Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channelQ28217136
Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factorsQ28217348
Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1)Q28221408
WNK1 activates ERK5 by an MEKK2/3-dependent mechanismQ28234991
WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephronQ28250388
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretionQ28506376
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain IIQ28581920
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinasesQ28583124
WNK kinases regulate thiazide-sensitive Na-Cl cotransportQ28584824
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic interventionQ28591574
The N-terminal ERK-binding site of MEK1 is required for efficient feedback phosphorylation by ERK2 in vitro and ERK activation in vivoQ28609067
Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cellsQ30781595
Role of with-no-lysine [K] kinases in the pathogenesis of Gordon's syndrome.Q31039816
Genome-wide detection of tissue-specific alternative splicing in the human transcriptomeQ31106050
Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretionQ33426861
WNK1 activates SGK1 to regulate the epithelial sodium channel.Q33900653
Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.Q34442840
WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.Q34464530
Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transportQ34777003
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.Q35651892
WNK kinases: molecular regulators of integrated epithelial ion transportQ35858400
Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.Q37328447
WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1).Q40339717
WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanismQ40388688
Properties of WNK1 and implications for other family membersQ40424747
Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.Q42479166
Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertensionQ44970101
The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytesQ48903239
WNK1 and WNK4 modulate CFTR activity.Q50640928
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosisQ56937812
Biological Cross-talk between WNK1 and the Transforming Growth Factor β-Smad Signaling PathwayQ61640683
P433issue33
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
glucocorticoidQ422549
P304page(s)25161-25167
P577publication date2010-06-04
P1433published inJournal of Biological ChemistryQ867727
P1476titleSerum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members
P478volume285

Reverse relations

cites work (P2860)
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Q37051467WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination