Current status of antivascular therapy and targeted treatment in the clinic

scientific article published on February 2008

Current status of antivascular therapy and targeted treatment in the clinic is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1080/02656730701824406
P698PubMed publication ID18214773

P50authorOlav DahlQ16188074
Øystein FlugeQ73922036
Erling Dahl BorkamoQ125330488
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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.Q27824811
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancerQ27824847
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.Q27824867
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Tumor angiogenesis: therapeutic implicationsQ27860595
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
Angiogenesis in cancer and other diseasesQ27861015
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumabQ28219257
Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancerQ28248186
Sunitinib versus interferon alfa in metastatic renal-cell carcinomaQ28282757
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Erlotinib in previously treated non-small-cell lung cancerQ29547546
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Drug penetration in solid tumoursQ29614404
Angiogenesis: an organizing principle for drug discovery?Q29614538
Epidermal growth factor receptor mutations in lung cancerQ29615474
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancerQ29616112
Molecular regulation of angiogenesis and lymphangiogenesisQ29616150
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancerQ29617440
Regulation of angiogenesis by hypoxia: role of the HIF systemQ29619187
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Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancerQ29622818
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Introduction: non-invasive thermometry for thermotherapyQ33222929
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Multicentric Study Comparing Intravesical Chemotherapy Alone and With Local Microwave Hyperthermia for Prophylaxis of Recurrence of Superficial Transitional Cell CarcinomaQ34272640
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancerQ34530109
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Trastuzumab in adjuvant breast cancer therapy. A model based cost-effectiveness analysisQ80203516
Cervical cancer: radiotherapy and hyperthermiaQ36497622
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A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancerQ36509678
Predicting benefit from anti-angiogenic agents in malignancyQ36534760
Adjuvant trastuzumab: a milestone in the treatment of HER-2-positive early breast cancerQ36593165
Cost-effectiveness analysis of cetuximab/irinotecan vs active/best supportive care for the treatment of metastatic colorectal cancer patients who have failed previous chemotherapy treatmentQ36609698
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Vascular damaging agentsQ36801914
Hyperthermia: a potent enhancer of radiotherapy.Q36817620
Rituximab therapy in malignant lymphomaQ36832102
Trastuzumab: triumphs and tribulationsQ36832109
Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer.Q36832116
Bevacizumab in the treatment of non-small-cell lung cancerQ36832129
HER2-positive breast cancer: current and future treatment strategiesQ36839672
Therapies directed against epidermal growth factor receptor in aerodigestive carcinomasQ36869621
Role of anti-angiogenesis agents in treating NSCLC: focus on bevacizumab and VEGFR tyrosine kinase inhibitorsQ36883658
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Bevacizumab in non small cell lung cancerQ36899890
Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancerQ37201832
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancerQ37219981
Anti-angiogenic action of hyperthermia by suppressing gene expression and production of tumour-derived vascular endothelial growth factor in vivo and in vitroQ37352738
EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanismsQ38314949
Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effectsQ38464708
Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumorsQ40144623
Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemiaQ40171279
Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancerQ40253380
Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapyQ40271356
ROS production and angiogenic regulation by macrophages in response to heat therapyQ40271384
Clinical study of recombinant adenovirus-p53 (Adp53) combined with hyperthermia in advanced cancer (a report of 15 cases).Q40493215
Arsenic trioxide induces selective tumour vascular damage via oxidative stress and increases thermosensitivity of tumoursQ40593312
Endothelial cells and hyperthermiaQ40635169
Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial.Q42626922
Phase I clinical study of AZD2171, an oral vascular endothelial growth factor signaling inhibitor, in patients with advanced solid tumorsQ43430750
Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemiaQ43565576
Researchers optimistic about sea change in cancer treatmentQ43636680
Combretastatin A-4 and hyperthermia;a potent combination for the treatment of solid tumorsQ43663314
CHOP plus rituximab--balancing facts and opinionQ43864042
Hyperthermia exhibits anti-vascular activity in the s.c. BT4An rat glioma: lack of interaction with the angiogenesis inhibitor batimastatQ43930195
Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disordersQ44265479
Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatmentQ44820379
Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomasQ44867750
Phase I/II trial of intravenous Doxil and whole abdomen hyperthermia in patients with refractory ovarian cancerQ44912086
Tumour-specific enhancement of thermoradiotherapy at mild temperatures by the vascular targeting agent 5,6-dimethylxanthenone-4-acetic acid.Q44942124
Vinca alkaloids: anti-vascular effects in a murine tumourQ46555781
Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumabQ46666366
Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trialsQ46735180
Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinibQ46735182
Vinblastine and hyperthermia target the neovasculature in BT(4)AN rat gliomas: therapeutic implications of the vascular phenotypeQ48784777
Reliability of temperature and SAR measurements at oesophageal tumour locations.Q51110049
Hyperthermia mediated liposomal drug delivery.Q51186669
Magnetic nanoparticles for interstitial thermotherapy--feasibility, tolerance and achieved temperatures.Q51918803
Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: results of a prospective phase I trial.Q52925886
Noninvasive magnetic resonance thermography of soft tissue sarcomas during regional hyperthermia: correlation with response and direct thermometry.Q52931245
Influence of neoadjuvant radiochemotherapy combined with hyperthermia on the quality of life in rectum cancer patients.Q52932508
Methods and potentials of magnetic resonance imaging for monitoring radiofrequency hyperthermia in a hybrid system.Q52936795
2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial.Q53243856
First results of triple-modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with stage IIB, III, and IVA cervical carcinoma.Q53271595
Mechanism of antitumor activity of tumor necrosis factor alpha with hyperthermia in a tumor necrosis factor alpha-resistant tumor.Q54309824
Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct.Q54573260
HER2 and responsiveness of breast cancer to adjuvant chemotherapy.Q54600960
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trialQ34551403
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.Q34554584
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trialQ34555503
Comparing antibody and small-molecule therapies for cancerQ34560075
Mechanisms of cutaneous toxicities to EGFR inhibitors.Q34567916
Sunitinib in patients with metastatic renal cell carcinomaQ34568166
Metronomic scheduling: the future of chemotherapy?Q34569946
The price of sight--ranibizumab, bevacizumab, and the treatment of macular degenerationQ34571631
Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancerQ34624378
BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemiaQ34651708
Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme.Q34744991
Hyperthermia in combined treatment of cancerQ34766163
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?Q34988256
Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancerQ35172774
Resistance to cytotoxic and anti-angiogenic anticancer agents: similarities and differencesQ35177652
The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management.Q35740647
Monoclonal antibodies as therapeutic agents for cancerQ35761687
Characterizing the tumor response to treatment with combretastatin A4 phosphateQ35793182
Vascular-targeting therapies for treatment of malignant disease.Q35805639
Effects of hyperthermia on the peripheral nervous system: a review.Q35809599
The role of gefitinib in lung cancer treatment.Q35817512
Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinomaQ35943769
Imaging angiogenesis: applications and potential for drug developmentQ36027611
Systemic therapy for colorectal cancerQ36029007
Angiogenic inhibitors: a new therapeutic strategy in oncologyQ36306264
Implications of increased tumor blood flow and oxygenation caused by mild temperature hyperthermia in tumor treatmentQ36336662
Re-setting the biologic rationale for thermal therapyQ36336673
Lymphangiogenesis in development and human diseaseQ36342355
Advances in oral therapy for multiple myeloma.Q36436240
Angiogenesis and cancer: A cross-talk between basic science and clinical trials (the "do ut des" paradigm).Q36442804
Cell biological effects of hyperthermia alone or combined with radiation or drugs: a short introduction to newcomers in the field.Q36497610
Tissue physiology and the response to heat.Q36497614
Hyperthermia and gene therapy: potential use of microPET imagingQ36497619
P433issue1
P304page(s)97-110
P577publication date2008-02-01
P1433published inInternational Journal of HyperthermiaQ332272
P1476titleCurrent status of antivascular therapy and targeted treatment in the clinic
P478volume24

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