Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement

scientific article published on February 2008

Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1473-3099(08)70018-5
P698PubMed publication ID18222164

P50authorChristopher J. SchofieldQ21165677
Alex John O'NeillQ53770069
Ian ChopraQ105819967
Keith MillerQ40739161
Mark H. WilcoxQ47356567
P2093author name stringPatrice Courvalin
Jean-Marie Frère
Uros Urleb
Martin Everett
Lloyd Czaplewski
Mike Dawson
P2860cites workAntibacterial discovery and development--the failure of success?Q47825932
Lack of development of new antimicrobial drugs: a potential serious threat to public healthQ48002635
Surveillance of antimicrobial resistance of invasive pathogens: the Estonian experienceQ50061144
Resistance in gram-negative bacteria: Enterobacteriaceae.Q51187082
Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD.Q52860325
Antibiotic resistance--action to promote new technologies: report of an EU Intergovernmental Conference held in Birmingham, UK, 12-13 December 2005.Q53249223
Effectiveness and nephrotoxicity of intravenous colistin for treatment of patients with infections due to polymyxin-only-susceptible (POS) gram-negative bacteria.Q53250268
Direct costs of multidrug-resistant Acinetobacter baumannii in the burn unit of a public teaching hospital.Q53883952
Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.Q54475713
Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wallQ58040446
Acinetobacter baumannii bloodstream infection while receiving tigecycline: a cautionary reportQ63859723
Serious Infections in the Intensive Care Unit: Pseudomonas aeruginosa and Acinetobacter baumanniiQ63859736
Where have all the antibiotic patents gone?Q79423620
Old polymyxins are back: is resistance close?Q80052849
Biomedical research. A cure for medicine's ailments?Q83018524
Antimicrobial resistance: paradox, actions and economicsQ83177259
Drug discovery in jeopardyQ22306297
Comparative genomics of multidrug resistance in Acinetobacter baumanniiQ25256737
The glycylcyclines: a comparative review with the tetracyclinesQ28238716
Challenges in identifying new antimicrobial agents effective for treating infections with Acinetobacter baumannii and Pseudomonas aeruginosaQ28256421
Antimicrobial drug development--the past, the present, and the futureQ34364369
Overview of nosocomial infections caused by gram-negative bacilliQ34444001
The biological cost of mutational antibiotic resistance: any practical conclusions?Q34554396
Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosaQ34555131
The worldwide emergence of plasmid-mediated quinolone resistanceQ34569740
Exploiting current understanding of antibiotic action for discovery of new drugs.Q34631418
Quinupristin-dalfopristin and linezolid: evidence and opinionQ34648292
The future challenges facing the development of new antimicrobial drugs.Q34988239
Why is big Pharma getting out of antibacterial drug discovery?Q35565576
Antibiotic resistance in Staphylococcus aureus: concerns, causes and curesQ35917130
The need for new antibioticsQ35937137
Antibacterial drug discovery in the 21st centuryQ35937143
Antibacterial drug discovery: is it all downhill from here?Q35937148
Antimicrobial drug resistance, regulation, and researchQ36026412
Mechanisms of action of newer antibiotics for Gram-positive pathogensQ36081079
Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threatQ36108084
TigecyclineQ36205663
Recently approved and investigational antibiotics for treatment of severe infections caused by Gram-positive bacteriaQ36228587
Can biotech deliver new antibiotics?Q36242043
The threat of antibiotic resistance in Gram-negative pathogenic bacteria: beta-lactams in peril!Q36242554
Resistance to antibiotics: are we in the post-antibiotic era?Q36282569
Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of AmericaQ36382134
Identification of high-risk enterococcal clonal complexes: global dispersion and antibiotic resistanceQ36552514
Parenteral and inhaled colistin for treatment of ventilator-associated pneumoniaQ36559388
The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?Q36634360
Anti-infective research and development--problems, challenges, and solutionsQ36689490
New lipophilic phthalimido- and 3-phenoxybenzyl sulfonates: inhibition of antigen 85C mycolyltransferase activity and cytotoxicityQ40216674
Analysis of mupirocin resistance and fitness in Staphylococcus aureus by molecular genetic and structural modeling techniquesQ40289356
Activity of tigecycline (GAR-936) against Acinetobacter baumannii strains, including those resistant to imipenemQ40290852
Sampling the antibiotic resistomeQ40357052
(Genome) size mattersQ41896915
Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wallQ44921136
Antimicrobials: new solutions badly neededQ44962251
Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3'')-Ii/AAC(6')-IId from Serratia marcescensQ46337932
A de novo designed inhibitor of D-Ala-D-Ala ligase from E. coliQ46699876
Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferaseQ46862305
P433issue2
P921main subjectGram-negative bacteriaQ632006
P304page(s)133-139
P577publication date2008-02-01
P1433published inLancet Infectious DiseasesQ15724248
P1476titleTreatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement
P478volume8

Reverse relations

cites work (P2860)
Q582160005-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases
Q34045186A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane
Q26783545A systematic review and critical assessment of incentive strategies for discovery and development of novel antibiotics
Q28543574A thermostable Salmonella phage endolysin, Lys68, with broad bactericidal properties against gram-negative pathogens in presence of weak acids
Q38008459Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal models
Q82430538An alkylaminoquinazoline restores antibiotic activity in Gram-negative resistant isolates
Q36322582Antibacterial and antibiotic resistance modulatory activities of leaves and bark extracts of Recinodindron heudelotii (Euphorbiaceae) against multidrug-resistant Gram-negative bacteria
Q38475604Antibacterial effect and proteomic analysis of graphene-based silver nanoparticles on a pathogenic bacterium Pseudomonas aeruginosa.
Q90617651Antimicrobial Resistance Prediction for Gram-Negative Bacteria via Game Theory-Based Feature Evaluation
Q35757930Antimicrobial activity of different Lactobacillus species against multi- drug resistant clinical isolates of Pseudomonas aeruginosa.
Q42003874Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues
Q38222114Antimicrobial peptides from scorpion venoms
Q41837042Antimicrobial peptoids are effective against Pseudomonas aeruginosa biofilms
Q64268541Approaches to the Structure-Based Design of Antivirulence Drugs: Therapeutics for the Post-Antibiotic Era
Q41923916Bacterial and antimicrobial susceptibility profile and the prevalence of sepsis among burn patients at the burn unit of Cipto Mangunkusumo Hospital
Q29616084Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America
Q37894832Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria
Q37760510Changes in the incidences of multidrug-resistant and extensively drug-resistant organisms isolated in a military medical center
Q53657637Characterization and sensitivity to antibiotics of bacteria isolated from the lower respiratory tract of ventilated patients hospitalized in intensive care units.
Q30726683Could chloramphenicol be used against ESKAPE pathogens? A review of in vitro data in the literature from the 21st century
Q36206767Crystallization and preliminary diffraction studies of SFC-1, a carbapenemase conferring antibiotic resistance
Q92398568Decoding inflammation, its causes, genomic responses, and emerging countermeasures
Q36652863Design, Synthesis and Evaluation of Triazole-Pyrimidine Analogues as SecA Inhibitors.
Q36649317Development of new 5-(chromene-3-yl)methylene-2,4-thiazolidinediones as antimicrobial agents
Q42100896Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity
Q40886052Efflux Pump Blockers in Gram-Negative Bacteria: The New Generation of Hydantoin Based-Modulators to Improve Antibiotic Activity
Q57777225Enhancement of antimicrobial activity by co-administration of poly(propylene imine) dendrimers and nadifloxacin
Q34357575Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead
Q34517482From microbial gene essentiality to novel antimicrobial drug targets
Q37487101Genome Sequence of Bacteriophage GG32, Which Can Infect both Salmonella enterica Serovar Typhimurium and Escherichia coli O157:H7
Q37355097Hospital infections, animal models and alternatives
Q34114983Hospital-acquired infections due to gram-negative bacteria
Q28475476How beta-lactam antibiotics enter bacteria: a dialogue with the porins
Q34215398In silico identification of common putative drug targets in Leptospira interrogans
Q48564199Incentivising innovation in antibiotic drug discovery and development: progress, challenges and next steps
Q38986360Multidrug efflux pumps and their role in antibiotic and antiseptic resistance: a pharmacodynamic perspective.
Q39776788New Peptide-based antimicrobials for tackling drug resistance in bacteria: single-cell fluorescence imaging.
Q28475848New antibiotic molecules: bypassing the membrane barrier of gram negative bacteria increases the activity of peptide deformylase inhibitors
Q37767653New definitions of extended-spectrum β-lactamase conferring worldwide emerging antibiotic resistance
Q33422956New disturbing trend in antimicrobial resistance of gram-negative pathogens
Q37287855Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection
Q37792479Polymyxins and their novel derivatives
Q36033050Prevalence of Device-associated Nosocomial Infections Caused By Gram-negative Bacteria in a Trauma Intensive Care Unit in Libya
Q34136100Prevalence of antimicrobial resistance among gram-negative isolates in an adult intensive care unit at a tertiary care center in Saudi Arabia
Q28486100Pseudomonas aeruginosa PA1006 is a persulfide-modified protein that is critical for molybdenum homeostasis
Q60915100ROS mediated antibacterial activity of photoilluminated riboflavin: A photodynamic mechanism against nosocomial infections
Q27677114Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid
Q38793887Role of Phenothiazines and Structurally Similar Compounds of Plant Origin in the Fight against Infections by Drug Resistant Bacteria
Q37872942Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria
Q38646502Structural and Enzymatic Characterization of ABgp46, a Novel Phage Endolysin with Broad Anti-Gram-Negative Bacterial Activity
Q33605661Structure-based discovery of antibacterial drugs
Q36791550Surveillance of multidrug resistant uropathogenic bacteria in hospitalized patients in Indian
Q39937286Synthesis and antimicrobial activities of 5-Arylidene-thiazolidine-2,4-dione derivatives.
Q54332036Synthesis and antimicrobial activities of oximes derived from O-benzylhydroxylamine as FabH inhibitors.
Q42871255Synthesis of new chalcone derivatives containing a rhodanine-3-acetic acid moiety with potential anti-bacterial activity
Q35021444Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2,4-thiazolidinediones.
Q37518925Targeting bacterial adherence inhibits multidrug-resistant Pseudomonas aeruginosa infection following burn injury
Q58742314Targeting the Bacterial Protective Armour; Challenges and Novel Strategies in the Treatment of Microbial Biofilm
Q34374054The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation
Q37786162The Dilemma of Multidrug-Resistant Gram-Negative Bacteria
Q28484507The binding mode of second-generation sulfonamide inhibitors of MurD: clues for rational design of potent MurD inhibitors
Q59485638The crisis of no new antibiotics—what is the way forward?
Q39862670The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria
Q34310470The enzymes of β-lactam biosynthesis
Q36825533The growing resistance of Klebsiella pneumoniae; the need to expand our antibiogram: case report and review of the literature.
Q41978763The target of daptomycin is absent from Escherichia coli and other gram-negative pathogens
Q38810063Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram-Negative Bacteria.
Q33897752Virtual screening for potential inhibitors of homology modeled Leptospira interrogans MurD ligase

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