Rearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines.

scientific article published on 27 April 2016

Rearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.00410-16
P932PMC publication ID4936145
P698PubMed publication ID27122587

P50authorLuis Martinez-SobridoQ55189492
Aitor NogalesQ56528198
P2093author name stringDavid J Topham
Marta L DeDiego
P2860cites workMutations at alternative 5' splice sites of M1 mRNA negatively affect influenza A virus viability and growth rateQ36949707
Efficacy and safety of a live attenuated influenza vaccine in adults 60 years of age and olderQ38378644
Generation of Recombinant Influenza Virus from Plasmid DNAQ39664696
Splicing of influenza A virus NS1 mRNA is independent of the viral NS1 proteinQ39697237
2A peptides provide distinct solutions to driving stop-carry on translational recoding.Q42546456
Superiority of live attenuated compared with inactivated influenza A virus vaccines in older, chronically ill adultsQ44955734
Mechanism of protective immunity against influenza virus infection in mice without antibodiesQ45756709
Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virusQ45791146
Live attenuated versus inactivated influenza vaccine in infants and young children.Q55043222
Identification of sequence changes in the cold-adapted, live attenuated influenza vaccine strain, A/Ann Arbor/6/60 (H2N2)Q64129941
Emerging roles for the influenza A virus nuclear export protein (NEP)Q21089600
Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomainQ27341132
Influenza: evolving strategies in treatment and preventionQ28299371
Replication-competent fluorescent-expressing influenza B virusQ28387786
Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine developmentQ28395006
The annual impact of seasonal influenza in the US: Measuring disease burden and costsQ29030744
Toward a universal influenza virus vaccine: prospects and challengesQ30223478
Plasmid-only rescue of influenza A virus vaccine candidates.Q30329368
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia.Q30342179
A review of vaccine research and development: human acute respiratory infections.Q30351377
Cellular immune correlates of protection against symptomatic pandemic influenza.Q30353819
Influenza A and B virus intertypic reassortment through compatible viral packaging signals.Q30364518
PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal modelsQ30385984
Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysisQ30408691
Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humansQ30412301
Influenza virus m2 ion channel protein is necessary for filamentous virion formationQ33826913
Influenza virus assembly: effect of influenza virus glycoproteins on the membrane association of M1 proteinQ33914921
Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virusQ33953302
Influenza virus M2 protein has ion channel activityQ34248853
Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP)--United States, 2012-13 influenza seasonQ34294175
Replication-competent influenza A viruses expressing a red fluorescent proteinQ35071285
Development of a mouse-adapted live attenuated influenza virus that permits in vivo analysis of enhancements to the safety of live attenuated influenza virus vaccineQ35110968
A nuclear export signal in the matrix protein of Influenza A virus is required for efficient virus replicationQ35943682
FluBlok, a recombinant hemagglutinin influenza vaccineQ36251189
Comparative immunogenicity of trivalent influenza vaccine administered by intradermal or intramuscular route in healthy adultsQ36289253
An overlapping protein-coding region in influenza A virus segment 3 modulates the host responseQ36554219
A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivityQ36592280
Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccinesQ36826849
The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus buddingQ36933890
P4510describes a project that usesImageJQ1659584
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectattenuated vaccineQ1810913
P304page(s)6291-6302
P577publication date2016-06-24
P1433published inJournal of VirologyQ1251128
P1476titleRearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines
P478volume90

Reverse relations

cites work (P2860)
Q52659466A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody.
Q60925671A Mechanism Underlying Attenuation of Recombinant Influenza A Viruses Carrying Reporter Genes
Q92340053A Novel Fluorescent and Bioluminescent Bireporter Influenza A Virus To Evaluate Viral Infections
Q38717627A live-attenuated influenza vaccine for H3N2 canine influenza virus.
Q40503815Canine influenza viruses with modified NS1 proteins for the development of live-attenuated vaccines
Q50054245Development of a novel equine influenza virus live-attenuated vaccine.
Q92538061Functional Characterization and Direct Comparison of Influenza A, B, C, and D NS1 Proteins in vitro and in vivo
Q40150645Functional Evolution of Influenza Virus NS1 Protein in Currently Circulating Human 2009 Pandemic H1N1 Viruses.
Q57093666Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in Humans
Q41933705Influenza A Virus Studies in a Mouse Model of Infection.
Q61798670Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model
Q40399903NS1 Protein Amino Acid Changes D189N and V194I Affect Interferon Responses, Thermosensitivity, and Virulence of Circulating H3N2 Human Influenza A Viruses
Q37347309NS1 Protein Mutation I64T Affects Interferon Responses and Virulence of Circulating H3N2 Human Influenza A Viruses.
Q64116962Novel Approaches for The Development of Live Attenuated Influenza Vaccines
Q40052241Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo
Q28076140Reverse Genetics Approaches for the Development of Influenza Vaccines
Q57466491Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine
Q38727207Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine
Q40072930The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression.
Q92964735Tyr82 Amino Acid Mutation in PB1 Polymerase Induces an Influenza Virus Mutator Phenotype
Q50308620Universal Vaccines and Vaccine Platforms to Protect against Influenza Viruses in Humans and Agriculture.

Search more.