The status and role of ErbB receptors in human cancer.

scientific article published on 05 January 2008

The status and role of ErbB receptors in human cancer. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YEXMP.2007.12.002
P698PubMed publication ID18279851

P50authorZdenek KolarQ39185544
Marián HajdúchQ73099106
Radek TrojanecQ73220350
P2093author name stringI Uberall
J Berkovcová
P2860cites workThe Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseQ24677033
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancerQ27824847
Cell signaling by receptor tyrosine kinasesQ27860474
Untangling the ErbB signalling networkQ27860884
Epidermal growth factor-related peptides and their receptors in human malignanciesQ28293442
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancerQ29547699
Cancer statistics, 2005Q29617572
The ErbB signaling network: receptor heterodimerization in development and cancerQ29617919
Chronic hepatitis B virus infection in Asian countriesQ30980179
Receptor signaling: when dimerization is not enoughQ33723925
c-erbB3 protein expression in ovarian cancerQ33841195
EGF mutant receptor vIII as a molecular target in cancer therapyQ33950534
Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.Q33968565
Gastric adenocarcinoma: pathomorphology and molecular pathologyQ34226916
The HER-2/neu oncogene in tumors of the gastrointestinal tractQ34311106
Lung cancer: intragenic ERBB2 kinase mutations in tumoursQ34354426
EGFR and cancer prognosisQ34399312
ErbB and HB-EGF signaling in heart development and function.Q34498400
Amplification of Her-2/neu gene in Her-2/neu-overexpressing and -nonexpressing breast carcinomas and their synchronous benign, premalignant, and metastatic lesions detected by FISH in archival materialQ34535370
c-erbB-2 in breast cancer: development of a clinically useful markerQ34683975
Prognostic and predictive value of HER2/neu oncogene in breast cancerQ34954864
The role of EGF-R expression on patient survival in lung cancer: a systematic review with meta-analysisQ34986549
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicityQ35660849
Signal transduction and oncogenesis by ErbB/HER receptorsQ35669114
The HER receptor family: a rich target for therapeutic developmentQ35669122
Focus on gastric cancer.Q35681321
Expression and gene copy number analysis of ERBB2 oncogene in prostate cancerQ35788601
Biological significance of c-erbB family oncogenes in head and neck cancerQ36078091
Expression of c-erbB3 protein in primary breast carcinomasQ36115645
Cancer biomarkers: knowing the present and predicting the futureQ36429381
Epidermal growth factor receptor biology in head and neck cancerQ36500973
ErbB receptor negative regulatory mechanisms: implications in cancerQ36545883
Expression and clinical significance of erb-B receptor family in hepatocellular carcinomaQ36622264
Lack of relationship between EGFR-1 immunohistochemical expression and prognosis in a multicentre clinical trial of 93 patients with advanced primary ovarian epithelial cancer (GINECO group)Q36695522
ErbB2 is required for ductal morphogenesis of the mammary glandQ37704948
Status of HER-2 in male and female breast carcinomaQ38458762
Estimates of the worldwide mortality from 25 cancers in 1990.Q39358305
Epidermal growth factor receptor family (EGFR, ErbB2-4) in gliomas and meningiomasQ40554806
Male breast carcinoma: correlation of ER, PR, Ki-67, Her2-Neu, and p53 with treatment and survival, a study of 65 casesQ40639249
Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cellsQ40676718
A multiparametric study on the prognostic value of epidermal growth factor receptor in operable breast carcinomaQ41053705
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.Q41615181
The autocrine loop of TGF-alpha/EGFR and brain tumorsQ41687874
Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)Q42004592
Expression of p160erbB-3 and p185erbB-2 in prostatic intraepithelial neoplasia and prostatic adenocarcinomaQ42491365
Role of exon-16-deleted HER2 in breast carcinomasQ42803579
Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. I. Correlation of receptor expression with prognostic factors in patients with ovarian cancer.Q43779560
HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stabilityQ45149773
Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breastQ46402523
Enhanced TGFalpha-EGFR expression and P53 gene alterations contributes to gastric tumors aggressiveness.Q47218285
Relationship of a new histological categorization of ductal carcinoma in situ of the breast with size and the immunohistochemical expression of p53, c-erb B2, bcl-2, and ki-67.Q47304057
Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: correlation with androgen independence.Q53345476
ERBB2 kinase domain mutation in a gastric cancer metastasis.Q53609172
Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer.Q53633593
Her-2-neu expression and progression toward androgen independence in human prostate cancer.Q53800928
Epidermal growth factor receptor (EGFR) status in primary colorectal tumors does not correlate with EGFR expression in related metastatic sites: implications for treatment with EGFR-targeted monoclonal antibodies.Q53878417
The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer.Q54242652
The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target.Q55477802
Immunohistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasmsQ71048246
Expression of epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) in gastric and colorectal carcinomas. An immunohistological study of 63 casesQ72807107
Angiogenesis, p53, and c-erbB-2 immunoreactivity and clinicopathological features in male breast cancerQ73339030
HER-2/neu amplification in benign breast disease and the risk of subsequent breast cancerQ73358692
Overexpression of c-erbB2 protein correlates with disease-stage and chromosomal gain at the c-erbB2 locus in non-small cell lung cancerQ73937759
ErbB kinases and NDF signaling in human prostate cancer cellsQ73945597
Oncogenes and male breast carcinoma: c-erbB-2 and p53 coexpression predicts a poor survivalQ74176628
Activation of epidermal growth factor receptor kinase in gastric carcinoma: a preliminary studyQ74194748
HER2 protein expression and gene amplification in androgen-independent prostate cancerQ74317132
Mutations and amplification of oncogenes in endometrial cancerQ77785073
Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology GroupQ78785334
Endometrial cancerQ81833884
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)79-89
P577publication date2008-01-05
P1433published inExperimental and Molecular PathologyQ15767470
P1476titleThe status and role of ErbB receptors in human cancer
P478volume84

Reverse relations

cites work (P2860)
Q39552974A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth.
Q54945917A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform.
Q38120594C-erbB2/HER2 in human gliomas, medulloblastomas, and meningiomas: a minireview
Q53533429Cancer Nanotechnology: Opportunities for Prevention, Diagnosis, and Therapy.
Q37363872Characterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma
Q33959887Clinical relevance of KRAS in human cancers
Q51062789Clinicopathology of EpCAM and EGFR in Human Epithelial Ovarian Carcinoma.
Q34103963Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention
Q33932286Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity
Q36924803Directing HER4 mRNA expression towards the CYT2 isoform by antisense oligonucleotide decreases growth of breast cancer cells in vitro and in vivo
Q37634419Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma
Q55070997EGFR signaling patterns are regulated by its different ligands.
Q38552978EGFR targeted therapies and radiation: Optimizing efficacy by appropriate drug scheduling and patient selection
Q44449930ERBB3 as an independent prognostic marker for nasopharyngeal carcinoma
Q33976619Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer
Q37263452ErbB receptors in the biology and pathology of the aerodigestive tract
Q35755192ErbB2 Is Necessary for ErbB4 Ligands to Stimulate Oncogenic Activities in Models of Human Breast Cancer
Q41816395Fasciclin 2, the Drosophila orthologue of neural cell-adhesion molecule, inhibits EGF receptor signalling
Q43912153Fatty acid synthase affects expression of ErbB receptors in epithelial to mesenchymal transition of breast cancer cells and invasive ductal carcinoma
Q44663445Fine needle aspirate cell blocks are reliable for detection of hormone receptors and HER-2 by immunohistochemistry in breast carcinoma
Q37355586HER2-positive male breast cancer: an update.
Q42288961HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice.
Q36986849Id-1: regulator of EGFR and VEGF and potential target for colorectal cancer therapy
Q37391086Identification of immunoreactive regions of homology between soluble epidermal growth factor receptor and α5-integrin
Q36925229Inherited and acquired alterations in development of breast cancer.
Q35083740KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations
Q92618791Overexpression of ERBB3 promotes proliferation, migration, and angiogenesis in nasopharyngeal carcinoma
Q31036763Reconstruction of temporal activity of microRNAs from gene expression data in breast cancer cell line
Q38758386Regulatory mechanisms of EGFR signalling during Drosophila eye development
Q37691771Targeting KRas-dependent tumour growth, circulating tumour cells and metastasis in vivo by clinically significant miR-193a-3p
Q37600910Targeting the EGF receptor ectodomain in the context of cancer
Q37856405The effect of cell-ECM adhesion on signalling via the ErbB family of growth factor receptors
Q39028181The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer
Q37015715The status of targeted agents in the setting of neoadjuvant radiation therapy in locally advanced rectal cancers
Q38905388Transcriptome meta-analysis reveals dysregulated pathways in nasopharyngeal carcinoma
Q34569071Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells.

Search more.