EGFR and cancer prognosis

scientific article

EGFR and cancer prognosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0959-8049(01)00231-3
P698PubMed publication ID11597399

P50authorJulianne GeeQ105289311
P2093author name stringHarper ME
Nicholson RI
P2860cites workImmunohistochemical demonstration of angiogenic growth factors and EGF receptor in hepatic metastases and primary human gastric cancerQ77533104
Epidermal growth factor-related peptides and their receptors in human malignanciesQ28293442
Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical resultsQ33832641
Transforming growth factor alpha and mouse models of human breast cancerQ33860847
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimersQ33888963
Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma.Q36138893
Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer researchQ40445359
Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancerQ40612368
Correlation of epidermal growth factor receptor and c-erbB2 oncogene product to known prognostic indicators of colorectal cancerQ41126348
In vitro and in vivo acceleration of the neoplastic phenotype of a low-tumorigenicity rat bladder carcinoma cell line by transfected transforming growth factor-alphaQ41475763
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cellsQ42805935
Epidermal growth factor receptor expression in breast cancer: association with response to endocrine therapy.Q44438798
Interrelationship between transforming growth factor-alpha and epidermal growth factor receptor in advanced gastric cancerQ44522288
Clinical results of transhiatal esophagectomy for carcinoma of the lower thoracic esophagus according to biological markersQ45013396
Prognostic value of EGFR and TGF-alpha in early laryngeal cancer treated with radiotherapy.Q53743664
The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer.Q54242652
Original Articles: Bladder Cancer: Long-Term Outcome Related to Epidermal Growth Factor Receptor Status in Bladder CancerQ63966066
Epidermal growth factor receptor expression in colorectal cancerQ68657749
Interaction between epidermal growth factor and its receptor in progression of human gastric carcinomaQ69816559
Prognostic value of epidermal growth factor receptor expression in endometrioid endometrial carcinomaQ71958889
Cytoplasmic c-erbB-2 protein expression correlates with survival in Dukes' B colorectal carcinomaQ72573279
Prognostic influence of the co-expression of epidermal growth factor receptor and c-erbB-2 protein in human lung adenocarcinomaQ72784859
The expression of p185(HER-2/neu) correlates with the stage of disease and survival in colorectal cancerQ73212054
Amplification of the c-met, c-erbB-2 and epidermal growth factor receptor gene in human gastric cancers: correlation to clinical featuresQ77223135
Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumorsQ77355550
Immunohistochemical study of c-erbB-2 protein in colorectal cancer and the correlation with patient survivalQ77432075
P304page(s)S9-15
P577publication date2001-09-01
P1433published inEuropean Journal of CancerQ332260
P1476titleEGFR and cancer prognosis
P478volume37 Suppl 4

Reverse relations

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Q38829535Esculetin Induces Apoptosis Through EGFR/PI3K/Akt Signaling Pathway and Nucleophosmin Relocalization.
Q24537669Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.
Q39955876Establishment and characterization of a cell line (IGSK-3) secreting human chorionic gonadotropin, adrenocorticotropic hormone and parathyroid hormone-related protein derived from primary poorly differentiated adenocarcinoma of the stomach
Q39773465Establishment and characterization of a novel human malignant peripheral nerve sheath tumor cell line, FMS-1, that overexpresses epidermal growth factor receptor and cyclooxygenase-2.
Q37040850Evaluating the Prevalence of the Epidermal Growth Factor Receptor in Transitional Cell Carcinoma of Bladder and its Relationship With Other Prognostic Factors
Q37206267Evaluation of EGFR as a prognostic and diagnostic marker for head and neck squamous cell carcinoma patients
Q27851592Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study
Q53602019Evaluation of involved proteins in colon adenocarcinoma: an interactome analysis.
Q39716869Evaluation of modified PEG-anilinoquinazoline derivatives as potential agents for EGFR imaging in cancer by small animal PET.
Q37446067Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer
Q59329233Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium
Q24803435Expanding the therapeutic repertoire of epidermal growth factor receptor blockade: radiosensitization
Q26828930Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities
Q38995370Expression and activity of EGFR in human cutaneous melanoma cell lines and influence of vemurafenib on the EGFR pathway
Q83855416Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma
Q52714617Expression of HNF4G and its potential functions in lung cancer.
Q40117486Expression of Rab5a in hepatocellular carcinoma: Possible involvement in epidermal growth factor signaling
Q38845254Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy
Q79522451Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: association with poor outcome
Q33592904Expression of epidermal growth factor receptor is an independent prognostic factor for esophageal squamous cell carcinoma
Q35803941Expression of the estrogen receptor α, progesterone receptor and epidermal growth factor receptor in papillary thyroid carcinoma tissues
Q37360495Extensive experience of disease control with gefitinib and the role of prognostic markers
Q38989275Extracellular region of epidermal growth factor receptor: a potential target for anti-EGFR drug discovery
Q47778400Extracellular vesicles as drivers of epithelial-mesenchymal transition and carcinogenic characteristics in normal prostate cells.
Q39884252F84, a quinazoline derivative, exhibits high potent antitumor activity against human gynecologic malignancies
Q64114238FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation
Q42115308Feasibility study of brain tumor delineation using immunolabeled gold nanorods
Q37771245First-line targeted therapies in the treatment of metastatic colorectal cancer - role of cetuximab
Q30419853Fluorodeoxyglucose positron emission tomography and tumor marker expression in non-small cell lung cancer
Q38612255Formulations of deoxycholic for therapy: a patent review (2011 - 2014).
Q37209926Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers
Q37698244From bench to bedside: the growing use of translational research in cancer medicine.
Q55093479From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo.
Q26853233G Protein-Coupled Receptor Signaling in Stem Cells and Cancer
Q46289176GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways.
Q38749499GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis
Q30155572GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration
Q36613924Gefitinib (ZD1839, Iressa) as palliative treatment in recurrent or metastatic head and neck cancer
Q37522211Gefitinib and celecoxib in advanced metastatic gastrointestinal tumors: a pilot feasibility study.
Q54564062Gefitinib and chemotherapy combination studies in five novel human non small cell lung cancer xenografts. Evidence linking EGFR signaling to gefitinib antitumor response.
Q46650874Gefitinib in patients with advanced non-small cell lung cancer (NSCLC): the expanded access protocol experience at the University of Pennsylvania
Q30544631Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study
Q36629392Gene expression profiles can predict panitumumab monotherapy responsiveness in human tumor xenograft models
Q39083974Generalized paired-agent kinetic model for in vivo quantification of cancer cell-surface receptors under receptor saturation conditions
Q37101367Genetic and chemical targeting of epithelial-restricted with serine box reduces EGF receptor and potentiates the efficacy of afatinib
Q33779432Genetic variants of EGF and VEGF predict prognosis of patients with advanced esophageal squamous cell carcinoma
Q35072797Genetic variations in multiple drug action pathways and survival in advanced stage non-small cell lung cancer treated with chemotherapy
Q92374402Genome-wide DNA copy number profiling and bioinformatics analysis of ovarian cancer reveals key genes and pathways associated with distinct invasive/migratory capabilities
Q39643103Global molecular dysfunctions in gastric cancer revealed by an integrated analysis of the phosphoproteome and transcriptome
Q39108385Global protein profiling reveals anti-EGFR monoclonal antibody 806-modulated proteins in A431 tumor xenografts
Q36821175Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor
Q37632159Glyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy
Q33663674GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptor
Q36814491Growth factor signalling in endocrine and anti-growth factor resistant breast cancer.
Q33699007HER kinase axis receptor dimer partner switching occurs in response to EGFR tyrosine kinase inhibition despite failure to block cellular proliferation
Q36061145HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy.
Q36724623HER2 Protein Overexpression and Gene Amplification in Plasmacytoid Urothelial Carcinoma of the Urinary Bladder
Q41767530HER2 and HER3 cooperatively regulate cancer cell growth and determine sensitivity to the novel investigational EGFR/HER2 kinase inhibitor TAK-285.
Q34974682HER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging
Q35827746HMMvar-func: a new method for predicting the functional outcome of genetic variants
Q52716394HOXA4, down-regulated in lung cancer, inhibits the growth, motility and invasion of lung cancer cells.
Q38469746Heat-shock protein 90 (Hsp90) as anticancer target for drug discovery: an ample computational perspective
Q80062040Heparin-binding epidermal growth factor-like growth factor isoforms and epidermal growth factor receptor/ErbB1 expression in bladder cancer and their relation to clinical outcome
Q36393289Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells
Q35769805High predictive value of epidermal growth factor receptor phosphorylation but not of EGFRvIII mutation in resected stage I non-small cell lung cancer (NSCLC)
Q33336861High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies
Q39934851High speed digital protein interaction analysis using microfluidic single molecule detection system
Q36449863High-sensitivity epidermal growth factor receptor immunostaining for colorectal carcinomas, compared with EGFR PharmDx™: a study of diagnostic accuracy
Q42847064Highly Sensitive Electrogenerated Chemiluminescence Biosensor in Profiling Protein Kinase Activity and Inhibition Using Gold Nanoparticle as Signal Transduction Probes
Q47589765Highly sensitive detection of epidermal growth factor receptor in lung cancer cells by aptamer-based target-/probe-mediated cyclic signal amplification
Q37379240Hydrogel-based protein array for quantifying epidermal growth factor receptor activity in cell lysates
Q39438159Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles
Q38659248ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection
Q24655085Identification of a Sam68 ribonucleoprotein complex regulated by epidermal growth factor
Q35806672Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia.
Q40502210IkappaBalphaM suppresses angiogenesis and tumorigenesis promoted by a constitutively active mutant EGFR in human glioma cells
Q33962349Illuminating epidermal growth factor receptor densities on filopodia through plasmon coupling
Q36662662Imaging characteristics of stage I non-small cell lung cancer on CT and FDG-PET: relationship with epidermal growth factor receptor protein expression status and survival
Q55032160Immune Landscape of Breast Cancers.
Q35623476Immunohistochemical Characterization of Three Monoclonal Antibodies Raised against the Epidermal Growth Factor and Its Receptor in Non-Small-Cell Lung Cancer: Their Potential Use in the Selection of Patients for Immunotherapy
Q39399928Immunohistochemical discrimination of wild-type EGFR from EGFRvIII in fixed tumour specimens using anti-EGFR mAbs ICR9 and ICR10.
Q43001429Immunohistochemical expression of CD95 (Fas), c-myc and epidermal growth factor receptor in hepatitis C virus infection, cirrhotic liver disease and hepatocellular carcinoma
Q37003601Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma
Q35770249Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for a multiphase approach to marker evaluation
Q34158993Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma
Q38633525Immunotherapy and targeted therapy for cervical cancer: an update
Q38367414Immunotherapy for lung cancer: for whom the bell tolls?
Q26751473Immunotoxin Therapies for the Treatment of Epidermal Growth Factor Receptor-Dependent Cancers
Q34258399Impact of EGFR mutation status on tumor response and progression free survival after first-line chemotherapy in patients with advanced non-small-cell lung cancer: a meta-analysis
Q37602294Impact of molecular markers on treatment selection in advanced colorectal cancer
Q33289414Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells
Q37118974Implications of EGFR PharmDx kit for cetuximab eligibility
Q100750039Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation
Q97542367Improved survival analysis by learning shared genomic information from pan-cancer data
Q35803276In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain.
Q39370112In vitro targeted imaging and delivery of camptothecin using cetuximab-conjugated multifunctional PLGA-ZnS nanoparticles
Q30372076In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft.
Q40825640In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.
Q35828611Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer.
Q36295330Inhibition of EGFR autophosphorylation plays an important role in the anti-breast cancer efficacy of the dithiocarbamate derivative TM208.
Q51137512Inhibition of EGFR, HER2 and HER3 signaling with AZD8931 alone and in combination with paclitaxel: phase i study in Japanese patients with advanced solid malignancies and advanced breast cancer.
Q34405324Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model
Q92702959Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds
Q36640322Initial evidence for Sec62 as a prognostic marker in advanced head and neck squamous cell carcinoma.
Q50126142Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment.
Q92570530Integrative Analysis of Cancer Omics Data for Prognosis Modeling
Q39635376Integrin beta1 over‐expression associates with resistance to tyrosine kinase inhibitor gefitinib in non‐small cell lung cancer
Q39990738Interleukin-2 potentiation of cetuximab antitumor activity for epidermal growth factor receptor-overexpressing gastric cancer xenografts through antibody-dependent cellular cytotoxicity
Q37289601Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes
Q39253894Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment.
Q57003964Investigation of ErbB1 and ErbB2 expression for therapeutic targeting in primary liver tumours
Q49892584Investigation of major genetic alterations in neuroblastoma.
Q36736349Investigational agents against platinum-resistant ovarian cancer
Q53551081Is EGFR a moving target during radiotherapy of carcinoma of the uterine cervix?
Q36100844KRAS mutant colorectal tumors: past and present
Q48140493KRAS mutations in microsatellite instable gastric tumours: impact of targeted treatment and intratumoural heterogeneity
Q35190688Kernel machine approach to testing the significance of multiple genetic markers for risk prediction
Q64988694Kinase-Inactivated EGFR Is Required for the Survival of Wild-Type EGFR-Expressing Cancer Cells Treated with Tyrosine Kinase Inhibitors.
Q49887882Kinase-targeted cancer therapies: progress, challenges and future directions
Q37398646Knock-down of amphiregulin inhibits cellular invasion in inflammatory breast cancer
Q33251283Label-free and real-time cell-based kinase assay for screening selective and potent receptor tyrosine kinase inhibitors using microelectronic sensor array
Q39400167Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity
Q37755493Lack of Cetuximab induced skin toxicity in a previously irradiated field: case report and review of the literature
Q54562020Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas.
Q46965909Lack of prognostic value of EGFR mutations in primary resected non-small cell lung cancer
Q37355729Lapatinib: new opportunities for management of breast cancer
Q92406179Lipid Profile and Aquaporin Expression under Oxidative Stress in Breast Cancer Cells of Different Malignancies
Q30596483Liquid crystal droplet-based amplification of microvesicles that are shed by mammalian cells
Q28261746Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
Q35144727Long-term cultured human neural stem cells undergo spontaneous transformation to tumor-initiating cells
Q53622278Loss of EGF-dependent cell proliferation ability on radioresistant cell HepG2-8960-R.
Q39690739Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins
Q33861083Lung cancer cytology: potential pitfalls and mimics - a review
Q34570799Luteolin is effective in the non-small cell lung cancer model with L858R/T790M EGF receptor mutation and erlotinib resistance
Q34047878Masked Chimeric Antigen Receptor for Tumor-Specific Activation
Q57105786Mechanisms Underlying the Action and Synergism of Trastuzumab and Pertuzumab in Targeting HER2-Positive Breast Cancer
Q36395100Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer
Q26745689Mechanisms underlying skin disorders induced by EGFR inhibitors
Q38427102Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man.
Q102220522Metabolic glycan labelling for cancer-targeted therapy
Q41343483MicroRNA-107-5p suppresses non-small cell lung cancer by directly targeting oncogene epidermal growth factor receptor
Q39433270MicroRNA-21 versus microRNA-34: Lung cancer promoting and inhibitory microRNAs analysed in silico and in vitro and their clinical impact
Q33590704MicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer
Q38003048MicroRNAs in pancreatic cancer metabolism
Q34473944Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging
Q30836260Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces.
Q31151322Microtiter cell-based assay for detection of agents that alter cellular levels of Her2 and EGFR.
Q35218002Mode of action of docetaxel - a basis for combination with novel anticancer agents
Q28484612Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression
Q36437230Modular nanotransporters: a versatile approach for enhancing nuclear delivery and cytotoxicity of Auger electron-emitting 125I.
Q56872060Modular pore-forming immunotoxins with caged cytotoxicity tailored by directed evolution
Q34489245Modulating the structure of EGFR with UV light: new possibilities in cancer therapy
Q58700723Molecular Diagnostics in Clinical Oncology
Q51019080Molecular alterations of EGFR in small intestinal adenocarcinoma.
Q38672075Molecular biology of anal squamous cell carcinoma: implications for future research and clinical intervention.
Q33969308Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study
Q36370600Molecular diagnostics of non-small cell lung cancer using mediastinal lymph nodes sampled by endoscopic ultrasound-guided needle aspiration
Q37825149Molecular imaging metrics to evaluate response to preclinical therapeutic regimens
Q30612000Molecular imaging of cancer cells using a bacteriophage-based 129Xe NMR biosensor
Q24678564Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin
Q35001415Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab
Q38562903Molecular mechanisms of squamous differentiation in urothelial cell carcinoma: a paradigm for molecular subtyping of urothelial cell carcinoma of the bladder
Q36772562Molecular predictors of EGFR-TKI sensitivity in advanced non-small cell lung cancer
Q38107276Molecularly targeted therapies for nonmelanoma skin cancers
Q35698114Morphological and molecular characteristics of HER2 amplified urothelial bladder cancer
Q36032533Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma
Q40808615Multiple differential expression networks identify key genes in rectal cancer
Q30474840Multiplex photoacoustic molecular imaging using targeted silica-coated gold nanorods
Q38804094Mutation analysis of EGFR and its correlation with the HPV in Indian cervical cancer patients.
Q55281004Mutational Screening in Tyrosine-Kinase Domain of erbB1 And erbB2 Genes.
Q35019550Nanomedical engineering: shaping future nanomedicines
Q91831250Nanoparticle-Based Contrast Agents for 129Xe HyperCEST NMR and MRI Applications
Q99712238Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance
Q35840361Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2.
Q45794953Naturally occurring phenolic acids modulate TPA-induced activation of EGFR, AP-1, and STATs in mouse epidermis.
Q38519582Necitumumab for non-small cell lung cancer
Q52957112Necitumumab for the treatment of stage IV metastatic squamous non-small-cell lung cancer.
Q37890404Necitumumab in the treatment of advanced non-small cell lung cancer: translation from preclinical to clinical development
Q39036930Necitumumab plus pemetrexed and cisplatin as first-line therapy in patients with stage IV non-squamous non-small-cell lung cancer (INSPIRE): an open-label, randomised, controlled phase 3 study
Q33579636Next generation of antibody therapy for cancer
Q34657670Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.
Q52653066Nimotuzumab enhances the sensitivity of non-small cell lung cancer cells to tumor necrosis factor-α by inhibiting the nuclear factor-кB signaling pathway.
Q104073421Non-metabolic role of UCK2 links EGFR-AKT pathway activation to metastasis enhancement in hepatocellular carcinoma
Q37036792Nonsurgical management of cervical cancer: locally advanced, recurrent, and metastatic disease, survivorship, and beyond
Q45864200Nonviral gene delivery to human ovarian cancer cells using arginine-grafted PAMAM dendrimer
Q41033340Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities
Q52599496Novel Systemic Therapies for Advanced Gastric Cancer.
Q35173073Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family
Q37772496Novel biomarkers of metastatic cancer
Q37487981Novel chemotherapy approaches for cervical cancer.
Q37622196Novel combination markers for predicting survival in patients with muscle invasive bladder cancer: USP18 and DGCR2.
Q28386773Novel insights into the molecular origins and treatment of lung cancer
Q38615458Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids.
Q38019657Novel targeted agents for gastric cancer
Q41953402Nuclear EGFR is required for cisplatin resistance and DNA repair
Q37282661Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer
Q40549193Nuclear factor kappa B (NFkappaB) dependent modulation of Epstein-Barr virus latent membrane protein 1 (LMP1) in epidermal growth factor receptor (EGFR) promoter activity
Q38810432Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival
Q39399252Nuclear translocation of pro-amphiregulin induces chemoresistance in gastric cancer.
Q37529397Oestrogen receptor negativity in breast cancer: a cause or consequence?
Q41144916Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation
Q38844554Oncogenic MCT-1 activation promotes YY1-EGFR-MnSOD signaling and tumor progression
Q37745280Oncogenic role of rab escort protein 1 through EGFR and STAT3 pathway
Q35569418One target, different effects: a comparison of distinct therapeutic antibodies against the same targets
Q49818115Optical molecular imaging for tumor detection and image-guided surgery.
Q36499255Optimal treatment of metastatic colorectal cancer
Q46427814Organometallic cobalamin anticancer derivatives for targeted prodrug delivery via transcobalamin-mediated uptake
Q55223569Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway.
Q38945259Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy
Q39690576Overexpressed epidermal growth factor receptor (EGFR)-induced progestin insensitivity in human endometrial carcinoma cells by the EGFR/mitogen-activated protein kinase signaling pathway
Q45232514Overexpression of EphB4, EphrinB2, and epidermal growth factor receptor in papillary thyroid carcinoma: A pilot study
Q47793305Overexpression of MutL homolog 1 and MutS homolog 2 proteins have reversed prognostic implications for stage I-II colon cancer patients
Q40125752Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: implications for Cetuximab-mediated therapy in recurrent/metastatic disease
Q45875804Oxymatrine inhibits non-small cell lung cancer via suppression of EGFR signaling pathway
Q37013280PD-1/PD-L1 expression in non-small-cell lung cancer and its correlation with EGFR/KRAS mutations
Q34996125PD-1/PD-L1 pathway in non-small-cell lung cancer and its relation with EGFR mutation
Q58110132PET Imaging Biomarkers of Anti-EGFR Immunotherapy in Esophageal Squamous Cell Carcinoma Models
Q34429075PET of EGFR expression with an 18F-labeled affibody molecule
Q54227938PI3K/PTEN/AKT/mTOR polymorphisms: association with clinical outcome in patients with head and neck squamous cell carcinoma receiving cetuximab-docetaxel.
Q39826662PKC-delta binds to E-cadherin and mediates EGF-induced cell scattering
Q36199783PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis
Q38354856Pancreatic cancer: diagnosis and treatments
Q88790399Past, present and future of gene expression-tailored therapy for lung cancer
Q37389526Pathogenesis of lung cancer signalling pathways: roadmap for therapies
Q90332238Peptide-Au Cluster Probe: Precisely Detecting Epidermal Growth Factor Receptor of Three Tumor Cell Lines at a Single-Cell Level
Q33870552Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion
Q38869428Personalized Radiation Oncology: Epidermal Growth Factor Receptor and Other Receptor Tyrosine Kinase Inhibitors
Q26774521Personalized medicine in gastric cancer: Where are we and where are we going?
Q37170005Pharmacokinetic-directed dosing of vandetanib and docetaxel in a mouse model of human squamous cell carcinoma
Q37112320Pharmacokinetic-pharmacodynamic modeling of the antitumor effect of TM208 and EGFR-TKI resistance in human breast cancer xenograft mice
Q40077599Pharmacological characterization of MP-412 (AV-412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor
Q45141053Phase I pharmacokinetic studies evaluating single and multiple doses of oral GW572016, a dual EGFR-ErbB2 inhibitor, in healthy subjects
Q42595256Phase I, dose-finding study of AZD8931, an inhibitor of EGFR (erbB1), HER2 (erbB2) and HER3 (erbB3) signaling, in patients with advanced solid tumors.
Q43181709Phase II study of gefitinib in combination with paclitaxel (P) and carboplatin (C) as second-line therapy for ovarian, tubal or peritoneal adenocarcinoma (1839IL/0074).
Q35154219Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study
Q54403335Phase II trial of erlotinib in patients with advanced non‑small‑cell lung cancer harboring epidermal growth factor receptor mutations: additive analysis of pharmacokinetics.
Q36717778Phosphorylated epidermal growth factor receptor and cyclooxygenase-2 expression in localized non-small cell lung cancer
Q39561256Phosphorylated insulin-like growth factor 1 receptor is implicated in resistance to the cytostatic effect of gefitinib in colorectal cancer cells
Q36235303Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter
Q35590357Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis
Q38900907Photoacoustic Imaging in Oncology: Translational Preclinical and Early Clinical Experience
Q26861053Plant sterols as anticancer nutrients: evidence for their role in breast cancer
Q33824400Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment
Q36046346Polymorphism in epidermal growth factor is related to clinical outcomes of metastatic colorectal cancer patients treated with cetuximab: a systematic review and meta-analysis
Q36385082Polymorphisms in intron 1 of the EGFR gene in non-small cell lung cancer patients
Q35538464Potential antitumor therapeutic application of Grimontia hollisae thermostable direct hemolysin mutants
Q35137787Potential roles of Centipede Scolopendra extracts as a strategy against EGFR-dependent cancers
Q36532110Potential use of humanized antibodies in the treatment of breast cancer.
Q37075379Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake.
Q39297048Preclinical and clinical development of afatinib: a focus on breast cancer and squamous cell carcinoma of the head and neck
Q37138420Preclinical studies of a Pro-antibody-drug conjugate designed to selectively target EGFR-overexpressing tumors with improved therapeutic efficacy
Q36788485Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer.
Q30364872Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution Microscopy
Q36880902Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma
Q36082772Prognostic Impact of Epidermal Growth Factor Receptor Overexpression in Patients with Cervical Cancer: A Meta-Analysis.
Q34086636Prognostic biomarkers in ovarian cancer
Q55059350Prognostic factors and genes associated with endometrial cancer based on gene expression profiling by bioinformatics analysis.
Q44468300Prognostic implications of EGFR and HER-2 alteration assessed by immunohistochemistry and silver in situ hybridization in gastric cancer patients following curative resection
Q43631346Prognostic role of epidermal growth factor receptor in head and neck cancer: a meta-analysis
Q51393573Prognostic significance of cyclooxygenase-2, epidermal growth factor receptor 1, and microvascular density in gastric cancer.
Q55209158Prognostic significance of epidermal growth factor receptor (EGFR) over expression in urothelial carcinoma of urinary bladder.
Q36293820Prognostic value of epidermal growth factor receptor expression in operable non-small cell lung carcinoma
Q37468304Prognostic value of epidermal growth factor receptors in gastric cancer: a survival analysis by Weibull model incorporating long-term survivors
Q46610690Prognostic value of immunohistochemical expression profile of epidermal growth factor receptor in urothelial bladder cancer
Q40265329Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells
Q39235953Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett's epithelium
Q36235591Promises and pitfalls in the prediction of antiepidermal growth factor receptor activity
Q38084617Promising new molecular targeted therapies in head and neck cancer
Q43743711Promising newer molecular-targeted therapies in head and neck cancer
Q33711287Promising outcomes of definitive chemoradiation and cetuximab for patients with esophageal squamous cell carcinoma
Q24677062Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3
Q91866079Protein Encapsulation of Experimental Anticancer Agents 5F 203 and Phortress: Towards Precision Drug Delivery
Q53598605Protein expression of HER2, 3, 4 in gastric cancer: correlation with clinical features and survival.
Q37417742Protein kinase inhibitors: contributions from structure to clinical compounds
Q51540449Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas. An immunohistochemical and fluorescence in situ hybridization study.
Q24337213Protein phosphorylation profiling using an in situ proximity ligation assay: phosphorylation of AURKA-elicited EGFR-Thr654 and EGFR-Ser1046 in lung cancer cells
Q33820267Protein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression
Q33275224Proteomic profiling of proteins dysregulted in Chinese esophageal squamous cell carcinoma
Q92192845Proteomics and Non-proteomics Approaches to Study Stable and Transient Protein-Protein Interactions
Q52663650Proteomics reveals novel protein associations with early endosomes in an epidermal growth factor-dependent manner.
Q89687320Proximate Analysis and Safety Profile of Farmed Edible Bird's Nest in Malaysia and Its Effect on Cancer Cells
Q35584250Quality of Life in Hormone Receptor–Positive HER-2+ Metastatic Breast Cancer Patients During Treatment with Letrozole Alone or in Combination with Lapatinib
Q36813117Quantification of epidermal growth factor receptor expression level and binding kinetics on cell surfaces by surface plasmon resonance imaging
Q41997137Quantitative Analysis of ErbB1 and ErbB2 Genes Amplification by a High Performance Liquid Chromatography
Q47748669Quantum-Dot-Based Theranostic Micelles Conjugated with an Anti-EGFR Nanobody for Triple-Negative Breast Cancer Therapy.
Q35051834RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer
Q33648830RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer
Q33569727RNA interference and nonviral targeted gene therapy of experimental brain cancer
Q53265601Radiolabeled cetuximab: dose optimization for epidermal growth factor receptor imaging in a head-and-neck squamous cell carcinoma model.
Q33872030Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer
Q39706629Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein
Q30436623Rational design for multifunctional non-liposomal lipid-based nanocarriers for cancer management: theory to practice.
Q33839177Rationale and design of LUX-Head & Neck 1: a randomised, Phase III trial of afatinib versus methotrexate in patients with recurrent and/or metastatic head and neck squamous cell carcinoma who progressed after platinum-based therapy
Q42918163Reactive oxygen species (ROS) reduce the expression of BRAK/CXCL14 in human head and neck squamous cell carcinoma cells
Q50186364Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery.
Q38899428Recent progress in protein-protein interaction study for EGFR-targeted therapeutics
Q90537630Receptor tyrosine kinase MET as potential target of multi-kinase inhibitor and radiosensitizer sorafenib in HNSCC
Q37118936Recurrent head and neck cancer: current treatment and future prospects.
Q35860644Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.
Q37581161Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors
Q47747965Reduced bikunin gene expression as a factor of poor prognosis in ovarian carcinoma
Q35917427Reformulating Tylocrebrine in Epidermal Growth Factor Receptor Targeted Polymeric Nanoparticles Improves Its Therapeutic Index
Q36738312Regulation of MAPKs by growth factors and receptor tyrosine kinases
Q35971560Regulation of ubiquitination-mediated protein degradation by survival kinases in cancer
Q38758386Regulatory mechanisms of EGFR signalling during Drosophila eye development
Q35602185Resistance to chemotherapy in advanced ovarian cancer: mechanisms and current strategies
Q36524455Revealing the role of VEGFA in clear cell sarcoma of the kidney by protein-protein interaction network and significant pathway analysis
Q37160382Review of cetuximab in the treatment of squamous cell carcinoma of the head and neck
Q90411189Review of emerging biomarkers in head and neck squamous cell carcinoma in the era of immunotherapy and targeted therapy
Q36461805Review of the treatment of non-small cell lung cancer with gefitinib
Q38916329RhoC mediates epidermal growth factor-stimulated migration and invasion in head and neck squamous cell carcinoma
Q38761493Rinsing paired-agent model (RPAM) to quantify cell-surface receptor concentrations in topical staining applications of thick tissues
Q57918768Risk factors differ for non-small-cell lung cancers with and without EGFR mutation: assessment of smoking and sex by a case-control study in Japanese
Q60935640Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage
Q59137936Role of bile acids in colon carcinogenesis
Q35125750Role of systemic peri-operative chemotherapy in management of transitional cell carcinoma of bladder
Q35572905Role of traditional and new biomarkers in breast carcinogenesis.
Q39015239S100A9 and EGFR gene signatures predict disease progression in muscle invasive bladder cancer patients after chemotherapy.
Q26798149SAM68: Signal Transduction and RNA Metabolism in Human Cancer
Q39832417SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline
Q40009259SPECT imaging with 99mTc-labeled EGFR-specific nanobody for in vivo monitoring of EGFR expression
Q73733584Screening for inducers of kinase degradation
Q34480613Secreted PLA2 induces proliferation in astrocytoma through the EGF receptor: another inflammation-cancer link.
Q36672321Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation
Q36616873Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib
Q30978860Selective regain of egfr gene copies in CD44+/CD24-/low breast cancer cellular model MDA-MB-468.
Q41476953Selective uptake of epidermal growth factor-conjugated gold nanoparticle (EGF-GNP) facilitates non-thermal plasma (NTP)-mediated cell death
Q35889589Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth
Q39000135Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Q53202983Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Q46946875Serum carcinoembryonic antigen level is associated with epidermal growth factor receptor mutations in recurrent lung adenocarcinomas
Q37347517Sex disparities in the association of lung adenocarcinoma with colorectal cancer
Q35579617Signaling network state predicts twist-mediated effects on breast cell migration across diverse growth factor contexts
Q38776725Silencing TAK1 alters gene expression signatures in bladder cancer cells
Q57292420Simultaneous evaluation of anti-EGFR-induced tumour and adverse skin effects in a microfluidic human 3D co-culture model
Q40230093Small interfering RNA targeting epidermal growth factor receptor enhances chemosensitivity to cisplatin, 5-fluorouracil and docetaxel in head and neck squamous cell carcinoma
Q37228581Small tyrosine kinase inhibitors as key molecules in the expression of metalloproteinases by solid tumors.
Q34710595Smart drugs: tyrosine kinase inhibitors in cancer therapy
Q37502708Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC.
Q37252262Somatic deletions of the polyA tract in the 3' untranslated region of epidermal growth factor receptor are common in microsatellite instability-high endometrial and colorectal carcinomas
Q99607554Somatic mutation detection efficiency in EGFR: a comparison between high resolution melting analysis and Sanger sequencing
Q24648133Somatic mutations of the epidermal growth factor receptor and non-small-cell lung cancer
Q37235024Somatic pharmacogenomics in cancer
Q36436693Some p53-binding proteins that can function as arbiters of life and death.
Q47155647Sortilin limits EGFR signaling by promoting its internalization in lung cancer
Q36137109Spheroid Culture of Head and Neck Cancer Cells Reveals an Important Role of EGFR Signalling in Anchorage Independent Survival
Q33869194Spotlight on differentially expressed genes in urinary bladder cancer.
Q39677393Stimulatory effects of the multi-kinase inhibitor sorafenib on human bladder cancer cells
Q38238743Strategies to overcome resistance to epidermal growth factor receptor monoclonal antibody therapy in metastatic colorectal cancer
Q35017477Stratification of non-small cell lung cancer patients for therapy with epidermal growth factor receptor inhibitors: the EGFR fluorescence in situ hybridization assay
Q40694780Study of Gefitinib and Pemetrexed as First-Line Treatment in Patients with Advanced Non-Small Cell Lung Cancer Harboring EGFR Mutation
Q39188570Study on invadopodia formation for lung carcinoma invasion with a microfluidic 3D culture device
Q39554373Successful treatment of epidermal growth factor receptor inhibitor-induced alopecia with doxycycline
Q38955418Suppression of EGFR-STAT3 signaling inhibits tumorigenesis in a lung cancer cell line.
Q50493805Surface engineering of gold nanoparticles for in vitro siRNA delivery.
Q24309274Survival of cancer cells is maintained by EGFR independent of its kinase activity
Q42726557Susceptibility to natural killer cell-mediated lysis of colon cancer cells is enhanced by treatment with epidermal growth factor receptor inhibitors through UL16-binding protein-1 induction
Q33637787Synergistic effects of combined platelet-activating factor receptor and epidermal growth factor receptor targeting in ovarian cancer cells
Q54347509Synthesis of caffeic acid amides bearing 2,3,4,5-tetra-hydrobenzo[b][1,4]dioxocine moieties and their biological evaluation as antitumor agents.
Q38940074Synthetic genistein glycosides inhibiting EGFR phosphorylation enhance the effect of radiation in HCT 116 colon cancer cells.
Q92856034TGF-β1 mediates lncRNA GAPLINC expression to promote the migration and invasion of non-small cell lung cancer
Q35381933TNFα-mediated loss of β-catenin/E-cadherin association and subsequent increase in cell migration is partially restored by NKX3.1 expression in prostate cells
Q36956724Tackling EGFR signaling with TACE antagonists: a rational target for metalloprotease inhibitors in cancer
Q40512067Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839).
Q37795802Targeted Agents in Ovarian Cancer
Q90478729Targeted Delivery of 111In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody
Q33664307Targeted Therapy of Cancer Using Photodynamic Therapy in Combination with Multi-faceted Anti-Tumor Modalities
Q36920799Targeted cancer therapies based on antibodies directed against epidermal growth factor receptor: status and perspectives
Q36659265Targeted coating with antigenic peptide renders tumor cells susceptible to CD8(+) T cell-mediated killing
Q36054970Targeted therapies for lung cancer: clinical experience and novel agents
Q37290448Targeted therapies in the management of metastatic bladder cancer
Q39213693Targeted therapies in the treatment of urothelial cancers
Q38815297Targeted therapy combined with radiotherapy in non-small-cell lung cancer: a review of the Oncologic Group for the Study of Lung Cancer (Spanish Radiation Oncology Society).
Q36294579Targeted therapy in gastroesophageal cancers: past, present and future
Q36957757Targeted therapy in rectal cancer.
Q52676608Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer.
Q36429516Targeting HER1/EGFR in cancer therapy: experience with erlotinib
Q34495463Targeting angiogenesis with integrative cancer therapies
Q40751673Targeting nuclear factor-kappa B to overcome resistance to chemotherapy.
Q51060657Targeting of EGFR and HER2 with therapeutic antibodies and siRNA: a comparative study in glioblastoma cells.
Q36400144Targeting of EGFR tyrosine kinase by ZD1839 ("Iressa") in androgen-responsive prostate cancer in vitro
Q36123983Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF.
Q36913614Targeting signaling pathways in epithelial ovarian cancer
Q37600910Targeting the EGF receptor ectodomain in the context of cancer
Q38757863Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab
Q36564975Targeting the epidermal growth factor receptor in the treatment of colorectal cancer: state of the art.
Q35982925The Association between EGFR and cMET Expression and Phosphorylation and Its Prognostic Implication in Patients with Breast Cancer.
Q36803187The Chicago Thoracic Oncology Database Consortium: A Multisite Database Initiative
Q49544424The Dawning of Translational Breast Cancer: From Bench to Bedside
Q49887941The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells.
Q92839866The RNA-binding protein Sam68 is critical for non-small cell lung cancer cell proliferation by regulating Wnt/β-catenin pathway
Q60960084The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients
Q35376123The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein
Q33786779The cooperation between hMena overexpression and HER2 signalling in breast cancer
Q33618747The correlation between programmed death-ligand 1 expression and driver gene mutations in NSCLC.
Q35247181The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells
Q35996651The current state of targeted agents in rectal cancer
Q36842728The developing trend of monoclonal antibodies in the treatment of colorectal cancer
Q28242493The emerging era of genomic data integration for analyzing splice isoform function
Q34343043The emerging role of nimotuzumab in the treatment of non-small cell lung cancer
Q38697702The enhanced tumor inhibitory effects of gefitinib and L-ascorbic acid combination therapy in non-small cell lung cancer cells
Q35546542The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells
Q34363400The epidermal growth factor receptor family in breast cancer
Q41721652The epigenetic regulation of CXCL14 plays a role in the pathobiology of oral cancers
Q90685224The inhibitory effect of ECG and EGCG dimeric procyanidins on colorectal cancer cells growth is associated with their actions at lipid rafts and the inhibition of the epidermal growth factor receptor signaling
Q35120839The interface between ErbB and non-ErbB receptors in tumor invasion: clinical implications and opportunities for target discovery
Q36201667The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies
Q45288154The pathologist and EGFR in 2004: I like you, nor do it
Q47952691The potential for cancer combination therapy with multi-targeted, single-protein pharmaceuticals
Q81408492The presence of carboxypeptidase-M in tumour cells signifies epidermal growth factor receptor expression in lung adenocarcinomas: the coexistence predicts a poor prognosis regardless of EGFR levels
Q33725976The quest to overcome resistance to EGFR-targeted therapies in cancer
Q49887915The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer
Q35094666The role of receptor tyrosine kinase inhibition in treating gastrointestinal malignancy
Q34902490The role of sphingosine kinase-1 in EGFRvIII-regulated growth and survival of glioblastoma cells
Q36583507The role of the epidermal growth factor receptor in breast cancer
Q38337192The route to personalized medicine in bladder cancer: where do we stand?
Q38706625The size-speed-force relationship governs migratory cell response to tumorigenic factors.
Q37086390The status and role of ErbB receptors in human cancer.
Q37496695The treatment of colorectal carcinoma with monoclonal antibodies: the importance of KRAS mutation analysis and EGFR status.
Q35674177Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer
Q39345120Therapeutic and preventive effects of an epidermal growth factor receptor inhibitor on oral squamous cell carcinoma
Q37137412Therapeutic approaches to target cancer stem cells
Q37310694Therapeutic strategy for treatment of metastatic non-small cell lung cancer
Q39170938Thyroid cancer cell resistance to gefitinib depends on the constitutive oncogenic activation of the ERK pathway
Q35530090Time-domain microfluidic fluorescence lifetime flow cytometry for high-throughput Förster resonance energy transfer screening
Q36557067Tissue-specific control of brain-enriched miR-7 biogenesis
Q92170097Transcriptome responses in blood reveal distinct biological pathways associated with arsenic exposure through drinking water in rural settings of Punjab, Pakistan
Q33747400Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases--the UK experience.
Q37218978Treatment of recurrent metastatic head and neck cancer: focus on cetuximab
Q34569071Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells.
Q33700990Triepitopic antibody fusions inhibit cetuximab-resistant BRAF and KRAS mutant tumors via EGFR signal repression
Q37049920Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial
Q37075319Tumor Targeting and Pharmacokinetics of a Near-Infrared Fluorescent-Labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5.
Q36402296Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer
Q58700887Tumor-specific delivery of therapeutic siRNAs by anti-EGFR immunonanoparticles
Q28115136Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer
Q82758574Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy
Q37338160Tumor-targeted delivery of siRNA by self-assembled nanoparticles
Q38718038Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery.
Q36218880Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
Q42533211Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia
Q54406282Up-regulation of EGF receptor and its ligands, AREG, EREG, and HB-EGF in oral lichen planus.
Q91826199Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway
Q36785507Upregulation of epidermal growth factor receptor 4 in oral leukoplakia
Q35172558Urothelial carcinomas: a focus on human epidermal receptors signaling
Q30511916Use of (64)Cu-labeled fibronectin domain with EGFR-overexpressing tumor xenograft: molecular imaging
Q37354097Using the theory of coevolution to predict protein-protein interactions in non-small cell lung cancer.
Q37301478VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab
Q40351380Vaccination with cetuximab mimotopes and biological properties of induced anti-epidermal growth factor receptor antibodies
Q34296399Variability in melanoma metalloproteinase expression profiling
Q78892615Vascular endothelial growth factor, CD68, and epidermal growth factor receptor expression and survival in patients with Stage II and Stage III colon carcinoma: a role for the host response in prognosis
Q47110408Volume doubling time of lung adenocarcinomas considering epidermal growth factor receptor mutation status of exon 19 and 21: three-dimensional volumetric evaluation
Q86741221WITHDRAWN: Improved therapeutic effectiveness by combining recombinant p14ARF with antisense complementary DNA of EGFR in laryngeal squamous cell carcinoma
Q37933675When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression
Q31150111Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells
Q24318720ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis
Q41686713ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin
Q54584675[Expressions of c-Cbl, Cbl-b and EGFR and its role of prognosis in NSCLC].
Q79405797[Therapy of severe cetuximab-induced acneiform eruptions with oral retinoid, topical antibiotic and topical corticosteroid]
Q79328028[Transitional bladder carcinoma TaG1: role of the EGFr tyrosin kinase activation in the cellular proliferation]
Q81771221[Tumor markers and biomarkers in squamous cell cancer of the head and neck]
Q33384492c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1
Q44184282gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth.
Q40068432her-2 upstream open reading frame effects on the use of downstream initiation codons
Q36132797miR-124 Regulates the Epithelial-Restricted with Serine Box/Epidermal Growth Factor Receptor Signaling Axis in Head and Neck Squamous Cell Carcinoma
Q38857823miR-133a inhibits cervical cancer growth by targeting EGFR.
Q47752840miR-202 inhibits cell proliferation, migration, and invasion by targeting EGFR in human bladder cancer
Q39373570p14(ARF) inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway
Q39706021p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.
Q92422648p21cip1/waf1 Coordinate Autophagy, Proliferation and Apoptosis in Response to Metabolic Stress
Q34583151p53, MDM2, eIF4E and EGFR expression in nasopharyngeal carcinoma and their correlation with clinicopathological characteristics and prognosis: A retrospective study
Q54194507pH dependence of ligand-induced human epidermal growth factor receptor activation investigated by molecular dynamics simulations.
Q33825091sZIP, an alternative splice variant of ZIP, antagonizes transcription repression and growth inhibition by ZIP
Q36791813shRNA and siRNA delivery to the brain