Is EGFR a moving target during radiotherapy of carcinoma of the uterine cervix?

scientific article published on 23 May 2007

Is EGFR a moving target during radiotherapy of carcinoma of the uterine cervix? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YGYNO.2007.04.019
P698PubMed publication ID17521713

P50authorOliver RiestererQ64681374
P2093author name stringBernhard Odermatt
I Frank Ciernik
Ferdinando Cerciello
Mohamed Sherweif
P2860cites workRadiotherapy plus cetuximab for squamous-cell carcinoma of the head and neckQ29619277
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Epidermal growth factor receptor inhibition strategies in oncologyQ34378885
EGFR and cancer prognosisQ34399312
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Epidermal growth factor receptor and response of head-and-neck carcinoma to therapyQ35669130
Epidermal growth factor receptor and tumor response to radiation: in vivo preclinical studiesQ35669133
Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical resultsQ35902858
Rationale and clinical experience with epidermal growth factor receptor inhibitors in gynecologic malignanciesQ36046225
Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ceQ38612684
Kinetics of EGFR expression during fractionated irradiation varies between different human squamous cell carcinoma lines in nude miceQ40396271
Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo.Q40451001
EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptorQ44306493
Epidermal growth factor receptor (EGFR) downstream molecules as response predictive markers for gefitinib (Iressa, ZD1839) in chemotherapy-resistant non-small cell lung cancerQ45073535
Expression of HER-2/neu, epidermal growth factor receptor, vascular endothelial growth factor, cyclooxygenase-2, estrogen receptor, and progesterone receptor in small cell and large cell neuroendocrine carcinoma of the uterine cervix: a clinicopathoQ46598246
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) negatively affect overall survival in carcinoma of the cervix treated with radiotherapyQ47800601
Expression of HER2neu (c-erbB-2) and epidermal growth factor receptor in cervical cancer: prognostic correlation with clinical characteristics, and comparison of manual and automated imaging analysisQ47872633
Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas.Q51988092
The prognostic value of epidermal growth factor receptor is related to tumor differentiation and the overall treatment time of radiotherapy in squamous cell carcinomas of the head and neck.Q52004398
The influence of epidermal growth factor receptor and tumor differentiation on the response to accelerated radiotherapy of squamous cell carcinomas of the head and neck in the randomized DAHANCA 6 and 7 study.Q53359192
G2/M cell cycle checkpoint is functional in cervical cancer patients after initiation of external beam radiotherapy.Q53665577
Epidermal Growth Factor Receptor Expression in Pretreatment Biopsies From Head and Neck Squamous Cell Carcinoma As a Predictive Factor for a Benefit From Accelerated Radiation Therapy in a Randomized Controlled TrialQ57618379
c-erbB-2 Oncoprotein expression is associated with poor prognosis in squamous cell carcinoma of the cervixQ72666313
Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiationQ73428673
Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancerQ77321070
Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervixQ77337863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectadaptive radiation therapyQ180507
P1104number of pages6
P304page(s)394-399
P577publication date2007-05-23
P1433published inGynecologic OncologyQ5625182
P1476titleIs EGFR a moving target during radiotherapy of carcinoma of the uterine cervix?
P478volume106

Reverse relations

cites work (P2860)
Q89924984Chemoradiotherapy response prediction model by proteomic expressional profiling in patients with locally advanced cervical cancer
Q35808930Efficient blockade of Akt signaling is a determinant factor to overcome resistance to matuzumab
Q37843137Epidermal growth factor receptor as a biomarker for cervical cancer
Q34244929Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies
Q53093760Phase 2 trial of erlotinib combined with cisplatin and radiotherapy in patients with locally advanced cervical cancer.
Q47095819Radiotherapy modulates expression of EGFR, ERCC1 and p53 in cervical cancer