Overexpression of EphB4, EphrinB2, and epidermal growth factor receptor in papillary thyroid carcinoma: A pilot study

scientific article published on 27 June 2014

Overexpression of EphB4, EphrinB2, and epidermal growth factor receptor in papillary thyroid carcinoma: A pilot study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HED.23694
P698PubMed publication ID24634162

P50authorGiriraj K SharmaQ81470773
P2093author name stringRizwan Masood
Dennis R Maceri
Vaninder K Dhillon
P2860cites workEphB4 expression and biological significance in prostate cancerQ24304334
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4Q24336334
A comprehensive pathway map of epidermal growth factor receptor signalingQ24672490
Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular developmentQ28145776
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancerQ28262641
Ephrins and Eph receptors in stem cells and cancerQ28292229
Ephrin signaling in vivo: look both waysQ28296703
Bidirectional Eph-ephrin signaling during axon guidanceQ28297294
Regulation of angiogenesis by Eph-ephrin interactionsQ28306625
EGF receptorQ28646107
Eph-ephrin bidirectional signaling in physiology and diseaseQ29617975
Ephrin-B3 ligand promotes glioma invasion through activation of Rac1.Q33256258
Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1.Q33737243
Eph receptors and ephrins in cancer: bidirectional signalling and beyondQ34021365
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesisQ34022315
P53 mutations in thyroid carcinoma: tidings from an old foe.Q34338919
EGFR and cancer prognosisQ34399312
Inhibition of tumor growth and angiogenesis by soluble EphB4.Q34770033
RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR.Q35124840
Receptor tyrosine kinase EphB4 is a survival factor in breast cancerQ35221906
How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapyQ35942401
Prognostic impact of EGF-receptor in papillary thyroid carcinomaQ35977349
Pathogenetic mechanisms in thyroid follicular-cell neoplasiaQ36430189
Paradoxes of the EphB4 receptor in cancerQ36812751
Identification of potential therapeutic targets in human head & neck squamous cell carcinomaQ37285806
Molecular pathology of thyroid cancer: diagnostic and clinical implicationsQ37337504
Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growthQ37682093
Routine central neck dissection in differentiated thyroid carcinoma: a systematic review and meta-analysisQ37980407
EphB4 is overexpressed in papillary thyroid carcinoma and promotes the migration of papillary thyroid cancer cellsQ39359780
EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migrationQ39602928
The significance of EphB4 and EphrinB2 expression and survival in head and neck squamous cell carcinomaQ40046746
EphB4 provides survival advantage to squamous cell carcinoma of the head and neckQ40292503
Distinct roles of ephrin-B2 forward and EphB4 reverse signaling in endothelial cells.Q40670502
Thyroid cancer nodal metastases: biologic significance and therapeutic considerations.Q41098136
Epidermal growth factor stimulates cell proliferation and inhibits iodide uptake of FRTL-5 cells in vitroQ41340452
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesisQ43072819
Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors.Q45958891
Automated selection of DAB-labeled tissue for immunohistochemical quantification.Q50494832
Co-expression of the genes encoding transforming growth factor-α and its receptor in papillary carcinomas of the thyroidQ53505149
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.Q53675468
BRAF(V600E) mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer.Q54398600
The association between elevated EphB4 expression, smoking status, and advanced-stage disease in patients with head and neck squamous cell carcinoma.Q54576061
Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomasQ70824085
Expression of growth factors and growth factor receptors in normal and tumorous human thyroid tissuesQ72328445
Prognostic factors in differentiated thyroid carcinomas and their implications for current staging classificationsQ80567974
P433issue7
P921main subjectpapillary thyroid cancerQ2292945
overexpressionQ61643320
P304page(s)964-969
P577publication date2014-06-27
P1433published inHead & NeckQ13703062
P1476titleOverexpression of EphB4, EphrinB2, and epidermal growth factor receptor in papillary thyroid carcinoma: A pilot study
P478volume37

Reverse relations

cites work (P2860)
Q47146373Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency.
Q41092476Ephrin-B2/Fc promotes proliferation and migration, and suppresses apoptosis in human umbilical vein endothelial cells
Q43083986Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition
Q58738086HMQ-T-B10 induces human liver cell apoptosis by competitively targeting EphrinB2 and regulating its pathway
Q64986508High serum Ephrin-B2 levels predict poor prognosis for patients with gastric cancer.
Q36352337Inhibition of FOXO1 by small interfering RNA enhances proliferation and inhibits apoptosis of papillary thyroid carcinoma cells via Akt/FOXO1/Bim pathway
Q36262217MicroRNA-96 plays an oncogenic role by targeting FOXO1 and regulating AKT/FOXO1/Bim pathway in papillary thyroid carcinoma cells
Q33599430Overexpression of erythropoietin-producing hepatocyte receptor B4 and ephrin-B2 is associated with estrogen receptor expression in endometrial adenocarcinoma
Q37723106The coexpression of EphB4 and EphrinB2 is associated with poor prognosis in HER2-positive breast cancer
Q53157139Whole exome sequencing identifies lncRNA GAS8-AS1 and LPAR4 as novel papillary thyroid carcinoma driver alternations.

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