Spotlight on differentially expressed genes in urinary bladder cancer.

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Spotlight on differentially expressed genes in urinary bladder cancer. is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...618255Z
P356DOI10.1371/JOURNAL.PONE.0018255
P8608Fatcat IDrelease_naa3irvi7be3jpxwdz5d434z7q
P932PMC publication ID3071699
P698PubMed publication ID21483670
P5875ResearchGate publication ID51042435

P50authorDimitrios SpandidosQ18701325
George I. LambrouQ37376221
Apostolos ZaravinosQ56419727
P2093author name stringDimitrios Volanis
Dimitris Delakas
P2860cites workIdentification of common differentially expressed genes in urinary bladder cancerQ21135503
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RKIP downregulates B-Raf kinase activity in melanoma cancer cellsQ28241040
Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosisQ28278590
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogeneQ28279136
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D-type cyclins in superficial and muscle-invasive bladder urothelial carcinoma: correlation with clinicopathological data and prognostic significanceQ33533392
Centrosome clustering and cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumorsQ33601875
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Molecular biology of bladder cancer: prognostic and clinical implications.Q36543207
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[Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) expression in superficial transitional cell bladder carcinoma]Q73166363
Significance of urinary epidermal growth factor and its receptor expression in human bladder cancerQ73311092
Predictive value of cell cycle markers p53, MDM2, p21, and Ki-67 in superficial bladder tumor recurrenceQ73347571
The prognostic value of angiogenesis factor expression for predicting recurrence and metastasis of bladder cancer after neoadjuvant chemotherapy and radical cystectomyQ73393234
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Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markersQ73937556
Molecular mediators of angiogenesis in bladder cancerQ74356111
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomasQ74614385
Numeric aberration of chromosome 17 is strongly correlated with p53 overexpression, tumor proliferation and histopathology in human bladder cancerQ77125013
MMP-9 activity in urine from patients with various tumors, as measured by a novel MMP activity assay using modified urokinase as a substrateQ78027229
[Immunohistochemical expression of p53, p21, p16, and cyclin D1 in superficial bladder cancer. A tissue microarray study]Q79321298
[Role of Ki-67, mutated gene-suppressor p53 and HER-2neu oncoprotein in the prognosis for the clinical course of bladder cancer]Q79876304
Extending the loop design for two-channel microarray experimentsQ79983438
Serum tissue inhibitor of metalloproteinase-2 (TIMP-2) and matrix metalloproteinase-2 in complex with the inhibitor (MMP-2:TIMP-2) as prognostic markers in bladder cancerQ79995929
Highly conserved sequence of exon 15 BRAF gene and KRAS codon 12 mutation among Greek patients with colorectal cancerQ80059973
Noninvasive diagnosis of bladder cancer by detection of matrix metalloproteinases (MMP-2 and MMP-9) and their inhibitor (TIMP-2) in urineQ80232980
Expression analysis of VEGFA, FGF2, TGFbeta1, EGF and IGF1 in human nasal polyposisQ80509721
Combination treatment with ionising radiation and gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor (EGFR) inhibitor, significantly inhibits bladder cancer cell growth in vitro and in vivoQ80564535
Mutations and differential expression of the ras family genes in human nasal polyposisQ81388189
Expression of VEGF in urinary bladder transitional cell carcinoma in an Iraqi population subjected to depleted uranium: an immunohistochemical studyQ83200461
Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of originQ83583616
Expression of basic fibroblast growth factor correlates with resistance to paclitaxel in human patient tumorsQ83897859
p16(INK4a) expression analysis as an ancillary tool for cytologic diagnosis of urothelial carcinomaQ84761597
Matrix metalloproteinases and their inhibitors in connective tissue remodelingQ37174661
Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategyQ37540810
Transforming growth factor-beta: multifunctional regulator of differentiation and developmentQ37583397
Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancerQ38320789
Preferential and novel activation of H-ras in human bladder carcinomasQ38348091
Regulation of Ras signaling specificity by protein kinase C.Q39458831
AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K.Q39791614
Expression of angiogenesis-related genes regulates different steps in the process of tumor growth and metastasis in human urothelial cell carcinoma of the urinary bladderQ39903524
Molecular profiling of bladder cancer: involvement of the TGF-beta pathway in bladder cancer progression.Q39982746
PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survivalQ39987929
Targeting EGFR in bladder cancerQ40095585
Micro-array analysis of the effect of post-transurethral bladder tumor resection urine on transforming growth factor-beta1 dependent gene expression in transitional cell carcinomaQ40348865
Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancerQ40532768
Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urineQ40667065
Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinomaQ40713063
Signal transduction pathways involving the Raf proto-oncogeneQ40733258
Identification of the osteopontin gene as a direct target of TP53.Q40755207
Expression and functions of EGF, FGF and TGFbeta-growth-factor family members and their receptors in invasive human transitional-cell-carcinoma cellsQ41116414
Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).Q41678253
The role of osteopontin in tumorigenesis and metastasis.Q41678469
Expression of transforming growth factors beta-1, beta 2 and beta 3 in human bladder carcinomasQ41911470
The prevalence of bcl-2, p53, and Ki-67 immunoreactivity in transitional cell bladder carcinomas and their clinicopathologic correlatesQ42451765
Viral DNA detection and RAS mutations in actinic keratosis and nonmelanoma skin cancersQ42461687
Expression of transforming growth factor beta1 and its receptors in normal human urothelium and human transitional cell carcinomasQ42470740
Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitusQ42521348
Ha-ras oncogenes are activated by somatic alterations in human urinary tract tumoursQ42818690
Expression of basic fibroblast growth factor, its receptors and syndecans in bladder cancer.Q43263196
BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma.Q43524289
DNA microarray expression profiling of bladder cancer allows identification of noninvasive diagnostic markersQ43875320
Implication of RAF and RKIP genes in urinary bladder cancerQ43890261
Urinary basic fibroblast growth factor in bladder cancer patients. Histopathological correlation and clinical potentialQ45032715
The role of TGF-beta-1 protein and TGF-beta-R-1 receptor in immune escape mechanism in bladder cancerQ46816755
Altered mRNA expression of the Rb and p16 tumor suppressor genes and of CDK4 in transitional cell carcinomas of the urinary bladder associated with tumor progression.Q47435187
Mutational analysis of the BRAF gene in transitional cell carcinoma of the bladderQ47911813
Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologiesQ48089758
Immunohistochemical positive stained p53 protein in bladder transitional cell carcinoma.Q51743957
Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials.Q51953901
Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.Q52089307
Identifying distinct classes of bladder carcinoma using microarrays.Q52111529
Osteopontin overexpression predicts poor prognosis of upper urinary tract urothelial carcinoma.Q53303542
p16ink4 immunoreactivity is a reliable marker for urothelial carcinoma in situ.Q53324615
Mutation Affecting the 12th Amino Acid of the c-Ha- ras Oncogene Product Occurs Infrequently in Human CancerQ53559076
Matrix metalloproteinase expression in the recurrence of superficial low grade bladder transitional cell carcinoma.Q53571539
p16(INK4a) expression in urinary bladder carcinoma.Q53585572
The epidermal growth factor receptor and the prognosis of bladder cancer.Q53797133
Activation of RAS family genes in urothelial carcinoma.Q54489900
RKIP and BRAF aberrations in human nasal polyps and the adjacent turbinate mucosae.Q54542900
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 agree with progression of ovarian endometriomasQ57903528
Statistical Methods for Identifying Differentially Expressed Genes in DNA MicroarraysQ58618312
Association of Angiogenesis Related Markers With Bladder Cancer Outcomes and Other Molecular MarkersQ59649562
Expression of transforming growth factor-beta 1 in prostate cancer.Q64893650
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinomaQ67832773
Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumoursQ69856767
Overexpression of p53 protein and its significance for recurrent progressive bladder tumoursQ71212915
C-erbB-2 in bladder cancer: molecular biology, correlation with epidermal growth factor receptors and prognostic valueQ71566796
p53 and erbB-2 protein overexpression are associated with early invasion and metastasis in bladder cancerQ71612104
Expression of p53 product in Chinese human bladder carcinomaQ72089540
Basic fibroblast growth factor and transforming growth factor beta-1: synergistic mediators of angiogenesis in vitroQ72098027
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)e18255
P577publication date2011-04-05
P1433published inPLOS OneQ564954
P1476titleSpotlight on differentially expressed genes in urinary bladder cancer
P478volume6

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cites work (P2860)
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Q36642294Role of the angiogenic components, VEGFA, FGF2, OPN and RHOC, in urothelial cell carcinoma of the urinary bladder
Q35119047Transcriptome profiling of a multiple recurrent muscle-invasive urothelial carcinoma of the bladder by deep sequencing

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