scholarly article | Q13442814 |
P2093 | author name string | Thanos D Halazonetis | |
Omar Zgheib | |||
Juergen Brugger | |||
Kristopher Pataky | |||
P2860 | cites work | MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 |
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response | Q24306765 | ||
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites | Q24306789 | ||
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response | Q24306807 | ||
The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response | Q24652479 | ||
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair | Q24669691 | ||
Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation | Q27642010 | ||
X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil | Q27655682 | ||
A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants | Q27731470 | ||
Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast | Q27930415 | ||
The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA | Q27934159 | ||
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. | Q27939003 | ||
Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX | Q28191330 | ||
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1 | Q28215916 | ||
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse | Q28289637 | ||
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks | Q28291639 | ||
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis | Q28509503 | ||
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage | Q29614218 | ||
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage | Q29614528 | ||
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks | Q30014828 | ||
Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1. | Q30947641 | ||
Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains | Q33293154 | ||
Tying the loose ends together in DNA double strand break repair with 53BP1. | Q35082739 | ||
Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast | Q35126538 | ||
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1 | Q36320732 | ||
Surviving the breakup: the DNA damage checkpoint. | Q36521813 | ||
Preferential dimethylation of histone H4 lysine 20 by Suv4-20 | Q36585568 | ||
Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage | Q39457941 | ||
Microcollimator for micrometer-wide stripe irradiation of cells using 20-30 keV X rays. | Q39821170 | ||
The tandem BRCT domain of 53BP1 is not required for its repair function | Q40219964 | ||
Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways | Q41861185 | ||
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. | Q42150641 | ||
Boundaries and physical characterization of a new domain shared between mammalian 53BP1 and yeast Rad9 checkpoint proteins. | Q42661170 | ||
Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. | Q44489693 | ||
Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2. | Q44960327 | ||
53BP1 exchanges slowly at the sites of DNA damage and appears to require RNA for its association with chromatin. | Q46445917 | ||
53BP1 oligomerization is independent of its methylation by PRMT1. | Q46809487 | ||
Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation. | Q50731881 | ||
Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain. | Q51081692 | ||
The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9-Rad9 interaction after DNA damage | Q64131921 | ||
53BP1, an activator of ATM in response to DNA damage | Q64388924 | ||
An engineered four-stranded coiled coil substitutes for the tetramerization domain of wild-type p53 and alleviates transdominant inhibition by tumor-derived p53 mutants | Q70866376 | ||
The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding | Q80515739 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1050-1058 | |
P577 | publication date | 2008-12-08 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks | |
P478 | volume | 29 |
Q39468621 | 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms |
Q92477502 | 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function |
Q29465773 | 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark |
Q48421018 | 53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope |
Q37713592 | 53BP1, BRCA1, and the choice between recombination and end joining at DNA double-strand breaks |
Q92380165 | 53BP1: a DSB escort |
Q26828847 | 53BP1: pro choice in DNA repair |
Q37299259 | A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining |
Q48515044 | A small molecule for theraNOstic targeting of cancer cells |
Q24339587 | A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei |
Q45068235 | ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks |
Q93116167 | CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites |
Q36033298 | CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks |
Q30578616 | Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks |
Q34142452 | Development and validation of 'AutoRIF': software for the automated analysis of radiation-induced foci |
Q35978288 | Dimerization Mediated by a Divergent Forkhead-associated Domain Is Essential for the DNA Damage and Spindle Functions of Fission Yeast Mdb1. |
Q42091851 | Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping |
Q28661754 | Double strand break repair functions of histone H2AX |
Q34391068 | Double-strand break repair: 53BP1 comes into focus |
Q34047330 | Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity |
Q48193812 | FLUORO/NO: A Nitric Oxide Donor with a Fluorescence Reporter |
Q27324256 | Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites |
Q57810095 | Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing |
Q27337186 | Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks |
Q64883630 | Integrating the DNA damage and protein stress responses during cancer development and treatment. |
Q35532757 | KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair |
Q64387249 | LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation |
Q50010857 | Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage |
Q64389353 | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein |
Q28534565 | Msl2 is a novel component of the vertebrate DNA damage response |
Q37287579 | Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members |
Q38133962 | Push back to respond better: regulatory inhibition of the DNA double-strand break response |
Q29465543 | RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. |
Q37421389 | RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks |
Q50494189 | Reading chromatin signatures after DNA double-strand breaks. |
Q35125130 | Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. |
Q38169747 | Role of 53BP1 in the regulation of DNA double-strand break repair pathway choice |
Q37420110 | Ser1778 of 53BP1 Plays a Role in DNA Double-strand Break Repairs |
Q63383440 | Shieldin – the protector of DNA ends |
Q30650918 | Single cell resolution in vivo imaging of DNA damage following PARP inhibition |
Q102058917 | Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break |
Q27660302 | Structural Insight into p53 Recognition by the 53BP1 Tandem Tudor Domain |
Q35063951 | Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1 |
Q34718519 | The 53BP1 homolog in C. elegans influences DNA repair and promotes apoptosis in response to ionizing radiation |
Q60044504 | The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity |
Q89866885 | The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication |
Q37843633 | The cellular response to DNA damage: a focus on MDC1 and its interacting proteins |
Q42474850 | The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres |
Q27676681 | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator |
Q34315565 | TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint |
Q33602611 | USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism |
Q36189465 | Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168 |
Q39154900 | Ultraviolet-B-mediated induction of protein-protein interactions in mammalian cells. |
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