Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation

scientific article published on 10 April 2008

Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2008.05403.X
P932PMC publication ID2648840
P698PubMed publication ID18410506
P5875ResearchGate publication ID5441195

P2093author name stringTammy Kielian
Nirmal K Phulwani
P2860cites workToll-like receptor signallingQ24570126
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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymeraseQ24671634
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The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator functionQ28190711
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Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin diseaseQ28298870
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Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functionsQ29617672
Astrocytes are active players in cerebral innate immunityQ29620562
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Microglial cells in astroglial cultures: a cautionary noteQ30480840
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Poly(ADP-ribose) polymerase in the cellular response to DNA damage, apoptosis, and diseaseQ33594926
A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologuesQ33862167
The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathyQ33936995
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in gliaQ34017468
The PARP superfamilyQ34335821
Physiology and pathophysiology of poly(ADP-ribosyl)ationQ34356113
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery.Q34559482
Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.Q34598646
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouseQ35018839
A twelve-year review of central nervous system bacterial abscesses; presentation and aetiologyQ35583333
Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunityQ35690894
PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse developmentQ35848522
Poly(ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications.Q35961428
Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscessQ36007420
Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation.Q36088029
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitorsQ36111918
TLR signaling.Q36627105
Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microgliaQ36671871
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscessesQ36676619
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathwayQ36712237
Central role for MyD88 in the responses of microglia to pathogen-associated molecular patternsQ36737319
Poly(ADP-ribose) polymerase inhibitors: new pharmacological functions and potential clinical implicationsQ36789751
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.Q36992615
Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cellsQ37070511
Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient gliaQ37416232
Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells.Q38337980
Inhibition of NOS-2 induction in LPS-stimulated J774.2 cells by 1, 5-isoquinolinediol, an inhibitor of PARP.Q40294740
Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1.Q40636858
Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthmaQ40669701
Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.Q40880071
Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in ratsQ42161912
Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytesQ43694507
Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transitionQ44762646
Glutamate-mediated overexpression of CD38 in astrocytes cultured with neuronesQ44804990
A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemiaQ44838339
NAD+ as a metabolic link between DNA damage and cell death.Q45161769
NADH can enter into astrocytes and block poly(ADP-ribose) polymerase-1-mediated astrocyte deathQ46324837
Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytesQ46654805
Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcriptionQ46735341
The intermediate filament GFAP is important for the control of experimental murine Staphylococcus aureus-induced brain abscess and Toxoplasma encephalitisQ47292513
Persistent immune activation associated with a mouse model of Staphylococcus aureus-induced experimental brain abscessQ47599486
Reactive astrocytes express PARP in the central nervous system of SOD(G93A) transgenic miceQ47955433
Decreased cADPR and increased NAD+ in the Cd38-/- mouseQ48512475
Bacterial brain abscess: microbiological features, epidemiological trends and therapeutic outcomesQ48529908
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemiaQ48616927
Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemiaQ48852641
Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.Q52095082
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.Q52534304
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturationQ61268478
Brain abscessQ73844091
Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitisQ74228038
Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expressionQ74775345
Antisense oligonucleotides to poly(ADP-ribose) polymerase-2 ameliorate colitis in interleukin-10-deficient miceQ78533501
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectastrocyteQ502961
P304page(s)578-590
P577publication date2008-04-10
P1433published inJournal of NeurochemistryQ6295643
P1476titlePoly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation
P478volume106

Reverse relations

cites work (P2860)
Q43268756Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.
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Q44445139Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1.
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