scholarly article | Q13442814 |
P2093 | author name string | Tammy Kielian | |
Nirmal K Phulwani | |||
P2860 | cites work | Toll-like receptor signalling | Q24570126 |
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? | Q24669960 | ||
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase | Q24671634 | ||
Prevalence of antimicrobial resistance in bacteria isolated from central nervous system specimens as reported by U.S. hospital laboratories from 2000 to 2002 | Q24797274 | ||
Immunopathogenesis of brain abscess | Q24804928 | ||
The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function | Q28190711 | ||
CD38: an ecto-enzyme at the crossroads of innate and adaptive immune responses | Q28280816 | ||
Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease | Q28298870 | ||
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling | Q29615457 | ||
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions | Q29617672 | ||
Astrocytes are active players in cerebral innate immunity | Q29620562 | ||
Fatal brain abscess due to community-associated methicillin-resistant Staphylococcus aureus strain USA300. | Q30444670 | ||
Infections of the central nervous system | Q30471856 | ||
Microglial cells in astroglial cultures: a cautionary note | Q30480840 | ||
Strategies for the management of bacterial brain abscess | Q31068606 | ||
Poly(ADP-ribose) polymerase in the cellular response to DNA damage, apoptosis, and disease | Q33594926 | ||
A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues | Q33862167 | ||
The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy | Q33936995 | ||
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia | Q34017468 | ||
The PARP superfamily | Q34335821 | ||
Physiology and pathophysiology of poly(ADP-ribosyl)ation | Q34356113 | ||
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery. | Q34559482 | ||
Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. | Q34598646 | ||
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse | Q35018839 | ||
A twelve-year review of central nervous system bacterial abscesses; presentation and aetiology | Q35583333 | ||
Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity | Q35690894 | ||
PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development | Q35848522 | ||
Poly(ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications. | Q35961428 | ||
Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess | Q36007420 | ||
Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation. | Q36088029 | ||
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors | Q36111918 | ||
TLR signaling. | Q36627105 | ||
Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia | Q36671871 | ||
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses | Q36676619 | ||
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway | Q36712237 | ||
Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns | Q36737319 | ||
Poly(ADP-ribose) polymerase inhibitors: new pharmacological functions and potential clinical implications | Q36789751 | ||
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. | Q36992615 | ||
Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells | Q37070511 | ||
Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia | Q37416232 | ||
Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells. | Q38337980 | ||
Inhibition of NOS-2 induction in LPS-stimulated J774.2 cells by 1, 5-isoquinolinediol, an inhibitor of PARP. | Q40294740 | ||
Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1. | Q40636858 | ||
Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma | Q40669701 | ||
Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks. | Q40880071 | ||
Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats | Q42161912 | ||
Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes | Q43694507 | ||
Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition | Q44762646 | ||
Glutamate-mediated overexpression of CD38 in astrocytes cultured with neurones | Q44804990 | ||
A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia | Q44838339 | ||
NAD+ as a metabolic link between DNA damage and cell death. | Q45161769 | ||
NADH can enter into astrocytes and block poly(ADP-ribose) polymerase-1-mediated astrocyte death | Q46324837 | ||
Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes | Q46654805 | ||
Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription | Q46735341 | ||
The intermediate filament GFAP is important for the control of experimental murine Staphylococcus aureus-induced brain abscess and Toxoplasma encephalitis | Q47292513 | ||
Persistent immune activation associated with a mouse model of Staphylococcus aureus-induced experimental brain abscess | Q47599486 | ||
Reactive astrocytes express PARP in the central nervous system of SOD(G93A) transgenic mice | Q47955433 | ||
Decreased cADPR and increased NAD+ in the Cd38-/- mouse | Q48512475 | ||
Bacterial brain abscess: microbiological features, epidemiological trends and therapeutic outcomes | Q48529908 | ||
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia | Q48616927 | ||
Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia | Q48852641 | ||
Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. | Q52095082 | ||
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. | Q52534304 | ||
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation | Q61268478 | ||
Brain abscess | Q73844091 | ||
Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis | Q74228038 | ||
Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression | Q74775345 | ||
Antisense oligonucleotides to poly(ADP-ribose) polymerase-2 ameliorate colitis in interleukin-10-deficient mice | Q78533501 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | astrocyte | Q502961 |
P304 | page(s) | 578-590 | |
P577 | publication date | 2008-04-10 | |
P1433 | published in | Journal of Neurochemistry | Q6295643 |
P1476 | title | Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation | |
P478 | volume | 106 |
Q43268756 | Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity. |
Q38089268 | Beyond DNA repair, the immunological role of PARP-1 and its siblings. |
Q46279808 | Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists. |
Q55604491 | Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? |
Q47335984 | Involvement of poly(ADP-ribose) polymerase-1 in development of spinal cord injury in Chinese individuals: a Chinese clinical study |
Q37794381 | Microglial activation in stroke: therapeutic targets |
Q44445139 | Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1. |
Q39374470 | Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury. |
Q42835885 | Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress. |
Q36348582 | NF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1 |
Q37822920 | PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration |
Q37377750 | PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis |
Q37667705 | PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury |
Q34421470 | PARP-1 inhibitors DPQ and PJ-34 negatively modulate proinflammatory commitment of human glioblastoma cells |
Q34025047 | PARP1 enhances inflammatory cytokine expression by alteration of promoter chromatin structure in microglia |
Q90645966 | Poly(ADP-Ribose) Polymerases in Host-Pathogen Interactions, Inflammation, and Immunity |
Q38134049 | Poly(ADP-ribose) polymerase 1 (PARP1) in atherosclerosis: from molecular mechanisms to therapeutic implications |
Q38009733 | Poly(ADP-ribose) polymerase-2: emerging transcriptional roles of a DNA-repair protein |
Q40019330 | Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β. |
Q47103033 | Role of poly (ADP-ribose) polymerase-1 and cytokines in acute renal injury in elderly Chinese patients with diabetes mellitus |
Q38047690 | Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes |
Q40458807 | Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy. |
Q61811112 | The Importance of Therapeutic Time Window in the Treatment of Traumatic Brain Injury |
Q51929863 | The paralogous genes RADICAL-INDUCED CELL DEATH1 and SIMILAR TO RCD ONE1 have partially redundant functions during Arabidopsis development. |
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