Role of chemotherapy and novel biological agents in the treatment of elderly patients with colorectal cancer

scientific article published on March 2008

Role of chemotherapy and novel biological agents in the treatment of elderly patients with colorectal cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3748/WJG.14.1812
P932PMC publication ID2699600
P698PubMed publication ID18350617
P5875ResearchGate publication ID51018200

P2093author name stringGerardo Rosati
Domenico Bilancia
P2860cites workBevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trialQ28036747
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Phase II trial of oxaliplatin and tegafur/uracil and oral folinic acid for advanced or metastatic colorectal cancer in elderly patientsQ33368070
Combination of irinotecan (CPT-11) plus 5-fluorouracil and leucovorin (FOLFIRI regimen) as first line treatment for elderly patients with metastatic colorectal cancer: a phase II trialQ33369393
XELOX (capecitabine plus oxaliplatin) as first-line treatment for elderly patients over 70 years of age with advanced colorectal cancerQ33370632
Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancerQ33372496
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancerQ33913953
The application of the principles of geriatrics to the management of the older person with cancerQ34014908
Chemotherapy in elderly patients with colorectal cancerQ34277764
Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating ScaleQ34425278
Capecitabine as adjuvant treatment for stage III colon cancerQ34429990
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study GroupQ34511070
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III studyQ34514696
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trialQ34555503
Raltitrexed (Tomudex): an alternative drug for patients with colorectal cancer and 5-fluorouracil associated cardiotoxicityQ36292188
Increasing underrepresentation of elderly patients with advanced colorectal or non-small-cell lung cancer in chemotherapy trialsQ36460967
Reduced dose intensity FOLFOX-4 as first line palliative chemotherapy in elderly patients with advanced colorectal cancerQ37425689
Clinical pharmacology of 5-fluorouracilQ38631279
Single-agent irinotecan as second-line weekly chemotherapy in elderly patients with advanced colorectal cancer.Q40467714
Irinotecan in combination with fluorouracil in a 48-hour continuous infusion as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a Spanish Cooperative Group for the Treatment of Digestive Tumors study.Q40507956
Advanced colorectal cancer in elderly patients: tolerance and efficacy of leucovorin and fluorouracil bolus plus continuous infusion.Q43573107
A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patientsQ43763447
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disordersQ44150789
First-line chemotherapy with fluorouracil and folinic acid for advanced colorectal cancer in elderly patients: a phase II studyQ44318064
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.Q44919656
Efficacy of 5-fluorouracil-based chemotherapy in elderly patients with metastatic colorectal cancer: a pooled analysis of clinical trialsQ45023406
A tailored regimen including capecitabine and oxaliplatin for treating elderly patients with metastatic colorectal carcinoma Southern Italy Cooperative Oncology Group trial 0108.Q45231756
Irinotecan/fluorouracil combination in first-line therapy of older and younger patients with metastatic colorectal cancer: combined analysis of 2,691 patients in randomized controlled trialsQ45287822
High activity and reduced neurotoxicity of bi-fractionated oxaliplatin plus 5-fluorouracil/leucovorin for elderly patients with advanced colorectal cancerQ46453492
Capecitabine/oxaliplatin, a safe and active first-line regimen for older patients with metastatic colorectal cancer: post hoc analysis of a large phase II studyQ46648452
Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group.Q50956129
Comprehensive geriatric assessment adds information to Eastern Cooperative Oncology Group performance status in elderly cancer patients: an Italian Group for Geriatric Oncology Study.Q51960759
Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older.Q53537752
Oxaliplatin: mechanism of action and antineoplastic activityQ60641680
Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancerQ61868308
UFT plus or minus calcium folinate for metastatic colorectal cancer in older patientsQ61917286
Influence of sex and age on fluorouracil clearanceQ68160118
Mechanism-based improvement in the therapeutic selectivity of 5-FU prodrug alone and under conditions of metabolic modulationQ71934546
Drug-company decision to end cancer trialQ73048641
Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II studyQ73544195
A multicenter, phase II trial of weekly irinotecan (CPT-11) in patients with previously treated colorectal carcinomaQ74635392
UFT and leucovorin: a review of its clinical development and therapeutic potential in the oral treatment of cancerQ77758522
Effect of hepatic dysfunction due to liver metastases on the pharmacokinetics of capecitabine and its metabolitesQ78074734
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
chemotherapyQ974135
P304page(s)1812-1822
P577publication date2008-03-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleRole of chemotherapy and novel biological agents in the treatment of elderly patients with colorectal cancer
P478volume14

Reverse relations

Q45378019Combination therapy for older men with colorectal cancer: are two drugs better than one?cites workP2860

Search more.