Dietary polyphenols as potential nutraceuticals in management of diabetes: a review

scientific article published on 13 August 2013

Dietary polyphenols as potential nutraceuticals in management of diabetes: a review is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1013806355
P356DOI10.1186/2251-6581-12-43
P932PMC publication ID3751738
P698PubMed publication ID23938049
P5875ResearchGate publication ID255788785

P50authorParvin MirmiranQ38640629
Fereidoun AziziQ63695821
P2093author name stringZahra Bahadoran
P2860cites workRole of AMP-activated protein kinase in mechanism of metformin actionQ22241898
AMP-Activated Protein Kinase in Metabolic Control and Insulin SignalingQ22241925
Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeineQ28206243
Dietary antioxidant intake and risk of type 2 diabetesQ28241083
Inhibition of alpha-glucosidase and alpha-amylase by flavonoidsQ28248695
Resveratrol increases glucose induced GLP-1 secretion in mice: a mechanism which contributes to the glycemic controlQ28743932
Polyphenols: food sources and bioavailabilityQ29618132
Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinaseQ30441622
Plant polyphenols as dietary antioxidants in human health and diseaseQ33717002
Impact of dietary polyphenols on carbohydrate metabolismQ33853862
Flavanols and anthocyanins in cardiovascular health: a review of current evidenceQ33853907
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetesQ33918445
Dietary intake and bioavailability of polyphenolsQ33985768
Diagnosis, prognosis, and treatment of impaired glucose tolerance and impaired fasting glucose.Q33990387
Genistein induces pancreatic beta-cell proliferation through activation of multiple signaling pathways and prevents insulin-deficient diabetes in miceQ33993882
Beneficial effects of green tea--a review.Q33994592
Estimated dietary flavonoid intake and major food sources of U.S. adultsQ34003717
Lignans and human healthQ34702636
Absorption and metabolism of polyphenols in the gut and impact on health.Q34840779
Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.Q34894220
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetesQ34953482
Red wine polyphenols induce EDHF-mediated relaxations in porcine coronary arteries through the redox-sensitive activation of the PI3-kinase/Akt pathwayQ35047460
Carbohydrate metabolism in non-insulin-dependent diabetes mellitusQ35665607
Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effectQ35751719
Vascular protection by dietary polyphenolsQ35908569
A review of the health effects of green tea catechins in in vivo animal modelsQ35966610
Antiangiogenic properties of natural polyphenols from red wine and green tea.Q35998188
Polyphenols: antioxidants and beyondQ36004012
Consumption of high-polyphenol dark chocolate improves endothelial function in individuals with stage 1 hypertension and excess body weightQ36413693
The effects of cranberry juice on serum glucose, apoB, apoA-I, Lp(a), and Paraoxonase-1 activity in type 2 diabetic male patients.Q36477547
Association between dietary phytochemical index and 3-year changes in weight, waist circumference and body adiposity index in adults: Tehran Lipid and Glucose studyQ36536060
Dietary total antioxidant capacity and the occurrence of metabolic syndrome and its components after a 3-year follow-up in adults: Tehran Lipid and Glucose StudyQ36565189
Type II diabetes mellitus and cardiovascular risk factors: Current therapeutic approachesQ36608474
Anthocyanins and anthocyanin-rich extracts: role in diabetes and eye functionQ36806099
The pathophysiology of cardiovascular disease in diabetes mellitus and the future of therapyQ36904452
Antioxidant phytochemicals against type 2 diabetesQ37173313
Long-term exposure to genistein improves insulin secretory function of pancreatic beta-cellsQ37288088
Reactive species and diabetes: counteracting oxidative stress to improve healthQ37600178
Oxidative stress and beta-cell dysfunctionQ37774895
Polyphenol-induced endothelium-dependent relaxations role of NO and EDHF.Q37809912
Anti-diabetic effects of resveratrol.Q37831928
Natural polyphenols and cardioprotectionQ37954433
Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in miceQ38352974
Anthocyanins from Chinese bayberry extract protect β cells from oxidative stress-mediated injury via HO-1 upregulationQ39618993
Fruit extracts of Momordica charantia potentiate glucose uptake and up-regulate Glut-4, PPAR gamma and PI3K.Q39801090
Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinaseQ40140368
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient miceQ40250591
Genistein acutely stimulates insulin secretion in pancreatic beta-cells through a cAMP-dependent protein kinase pathwayQ40299334
Apple procyanidins decrease cholesterol esterification and lipoprotein secretion in Caco-2/TC7 enterocytesQ40485371
Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam StudyQ40603438
Functional herbal food ingredients used in type 2 diabetes mellitus.Q42176779
Ameliorative effect of quercetin on memory dysfunction in streptozotocin-induced diabetic ratsQ42974264
Grape seed proanthocyanidins attenuate vascular smooth muscle cell proliferation via blocking phosphatidylinositol 3-kinase-dependent signaling pathwaysQ43154423
Synergistic effect of phytochemicals in combination with hypoglycemic drugs on glucose uptake in myotubesQ43297347
Fruit and vegetable consumption and risk factors for cardiovascular diseaseQ43970220
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose productionQ44064091
Green tea catechin improves microsomal phospholipase A2 activity and the arachidonic acid cascade system in the kidney of diabetic ratsQ44135713
Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway.Q44391225
Effects of dietary supplementation with isoflavones from red clover on ambulatory blood pressure and endothelial function in postmenopausal type 2 diabetesQ44563278
Role of oxidative stress in pancreatic beta-cell dysfunctionQ44883070
Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humansQ45197163
The association of dietary phytochemical index and cardiometabolic risk factors in adults: Tehran Lipid and Glucose StudyQ45842800
Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and insulin sensitivity.Q45914726
Antidiabetic and antioxidant effects of polyphenols in brown alga Ecklonia stolonifera in genetically diabetic KK-A(y) miceQ46287541
Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic ratsQ46363480
Dietary polyphenols decrease glucose uptake by human intestinal Caco-2 cells.Q46367447
Altered hyperlipidemia, hepatic steatosis, and hepatic peroxisome proliferator-activated receptors in rats with intake of tart cherry.Q46504366
Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathyQ46818327
Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic miceQ46904894
Hypoglycemic effects of a phenolic acid fraction of rice bran and ferulic acid in C57BL/KsJ-db/db miceQ46921774
Microarray profiling of gene expression in human adipocytes in response to anthocyaninsQ46948472
Effect of broccoli sprouts on insulin resistance in type 2 diabetic patients: a randomized double-blind clinical trial.Q51357683
Broccoli sprouts powder could improve serum triglyceride and oxidized LDL/LDL-cholesterol ratio in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial.Q51361259
Hypoglycemic and hypolipidemic effects of polyphenols from burs of Castanea mollissima Blume.Q54434322
The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice.Q55039250
Broccoli sprouts reduce oxidative stress in type 2 diabetes: a randomized double-blind clinical trialQ58420466
High-polyphenol chocolate reduces endothelial dysfunction and oxidative stress during acute transient hyperglycaemia in Type 2 diabetes: a pilot randomized controlled trialQ59159563
Dietary Intake and Major Food Sources of Polyphenols in Finnish AdultsQ59512131
Green tea polyphenols inhibit the sodium-dependent glucose transporter of intestinal epithelial cells by a competitive mechanismQ73213208
Resveratrol inhibits insulin secretion from rat pancreatic isletsQ79309967
Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum ThunbQ79758268
Effects of dietary apple polyphenol on adipose tissues weights in Wistar ratsQ80036895
Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorptionQ80216461
Dose-dependent hypocholesterolemic actions of dietary apple polyphenol in rats fed cholesterolQ80815603
Purple corn anthocyanins dampened high-glucose-induced mesangial fibrosis and inflammation: possible renoprotective role in diabetic nephropathyQ84036640
Cardioprotective effects of grape seed proanthocyanidins extracts in streptozocin induced diabetic ratsQ95816914
P433issue1
P921main subjectpolyphenolQ290439
P304page(s)43
P577publication date2013-08-13
P1433published inJournal of diabetes and metabolic disordersQ27724561
P1476titleDietary polyphenols as potential nutraceuticals in management of diabetes: a review
P478volume12

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cites work (P2860)
Q49357556A computationally driven analysis of the polyphenol-protein interactome.
Q99583856Adsorption and desorption characteristics of polyphenols from Eucommia ulmoides Oliv. leaves with macroporous resin and its inhibitory effect on α-amylase and α-glucosidase
Q38658544Alcohol drinking patterns and risk of diabetes: a cohort study of 70,551 men and women from the general Danish population
Q58076554Alteration in sperm characteristics, endocrine balance and redox status in rats rendered diabetic by streptozotocin treatment: attenuating role of Loranthus micranthus
Q64121728Amelioration of diabetic nephropathy using pomegranate peel extract-stabilized gold nanoparticles: assessment of NF-κB and Nrf2 signaling system
Q33877627An Overview of Herbal Products and Secondary Metabolites Used for Management of Type Two Diabetes
Q57464964Anti-Atherosclerotic Effect of a Polyphenol-Rich Ingredient, Oleactiv, in a Hypercholesterolemia-Induced Hamster Model
Q26866115Anti-hyperglycemic and insulin sensitizer effects of turmeric and its principle constituent curcumin
Q42121157Anticancer and antioxidant activity of bread enriched with broccoli sprouts.
Q26771961Antidiabetic properties of dietary flavonoids: a cellular mechanism review
Q64093008Antimicrobial activities of green synthesized gums-stabilized nanoparticles loaded with flavonoids
Q37132303Antioxidant and Antihyperlipidemic Effects of Campomanesia adamantium O. Berg Root
Q92154881Antioxidant and Enzyme Inhibitory Properties of the Polyphenolic-Rich Extract from an Ancient Apple Variety of Central Italy (Mela Rosa dei Monti Sibillini)
Q37051814Apple phenolics as nutraceuticals: assessment, analysis and application
Q42823627Aspalathin improves glucose and lipid metabolism in 3T3-L1 adipocytes exposed to palmitate
Q46610209Aspalathin, a dihydrochalcone C-glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis.
Q64226370Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways
Q52904307Assessing similarity analysis of chromatographic fingerprints of Cyclopia subternata extracts as potential screening tool for in vitro glucose utilisation.
Q40717892Association between dietary fibre intake and fruit, vegetable or whole-grain consumption and the risk of CVD: results from the PREvención con DIeta MEDiterránea (PREDIMED) trial
Q96304001Association between phytochemical index and metabolic syndrome
Q39149192Attenuation of Diabetic Conditions by Sida rhombifolia in Moderately Diabetic Rats and Inability to Produce Similar Effects in Severely Diabetic in Rats
Q61804755Autumn olive (Elaeagnus umbellata Thunb.) berry reduces fasting and postprandial glucose levels in mice
Q38903541Beneficial effects of a red wine polyphenol extract on high-fat diet-induced metabolic syndrome in rats
Q64951075Biomarkers of Oxidative Stress in Metabolic Syndrome and Associated Diseases.
Q92702118Can Agro-Industrial By-Products Rich in Polyphenols be Advantageously Used in the Feeding and Nutrition of Dairy Small Ruminants?
Q64260158Can Carob-Fruit-Extract-Enriched Meat Improve the Lipoprotein Profile, VLDL-Oxidation, and LDL Receptor Levels Induced by an Atherogenic Diet in STZ-NAD-Diabetic Rats?
Q36675681Chemometrics Optimized Extraction Procedures, Phytosynergistic Blending and in vitro Screening of Natural Enzyme Inhibitors Amongst Leaves of Tulsi, Banyan and Jamun
Q45418195Chinese Olive (Canarium album L.) Fruit Extract Attenuates Metabolic Dysfunction in Diabetic Rats
Q49838854Cocos nucifera in combination with metformin for modulation of diabetic symptoms in streptozotocin induced diabetic rats
Q55665215Componential profile and amylase inhibiting activity of phenolic compounds from Calendula officinalis L. leaves.
Q26765972Could gestational diabetes mellitus be managed through dietary bioactive compounds? Current knowledge and future perspectives
Q28263149Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview
Q37449908Curcumin and long-chain Omega-3 polyunsaturated fatty acids for Prevention of type 2 Diabetes (COP-D): study protocol for a randomised controlled trial.
Q37497107Delphinidin-Rich Maqui Berry Extract (Delphinol®) Lowers Fasting and Postprandial Glycemia and Insulinemia in Prediabetic Individuals during Oral Glucose Tolerance Tests
Q30239828Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function.
Q47330811Diet and risk of diabetic retinopathy: a systematic review
Q64258005Dietary Patterns during Pregnancy Are Associated with the Risk of Gestational Diabetes Mellitus: Evidence from a Chinese Prospective Birth Cohort Study
Q33568506Dietary inclusion effects of phytochemicals as growth promoters in animal production.
Q40282565Dietary phytochemical index and the risk of insulin resistance and β-cell dysfunction: a prospective approach in Tehran lipid and glucose study
Q53314874Differential α-amylase/α-glucosidase inhibitory activities of plant-derived phenolic compounds: a virtual screening perspective for the treatment of obesity and diabetes.
Q97527952Effect of Berry Polyphenols on Glucose Metabolism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Q92009014Effect of Daily Consumption of Cranberry Beverage on Insulin Sensitivity and Modification of Cardiovascular Risk Factors in Obese Adults: A Pilot Randomized Placebo-Controlled Study
Q57472101Effect of Leaf Powder on Postprandial Blood Glucose Response: In Vivo Study on Saharawi People Living in Refugee Camps
Q41681214Effect of livingstonepotato (Plectranthus esculenthus N.E.Br) on hyperglycemia, antioxidant activity and lipid metabolism of streptozotocin induced diabetic rats
Q46893337Effect of pH on the chemical modification of quercetin and structurally related flavonoids characterized by optical (UV-visible and Raman) spectroscopy
Q30391190Effect of partial replacement of wheat flour with high quality cassava flour on the chemical composition, antioxidant activity, sensory quality, and microbial quality of bread
Q90643187Effect of vegetable juice consumption prior to eating rice on postprandial blood glucose and insulin levels
Q98465985Effects of Securigera securidaca (L.) Degen & Dorfl seed extract combined with glibenclamide on paraoxonase1 activity, lipid profile and peroxidation, and cardiovascular risk indices in diabetic rats
Q42056613Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats.
Q37405000Evaluation of Hypoglycemic and Genotoxic Effect of Polyphenolic Bark Extract from Quercus sideroxyla.
Q38808695Exploration of natural enzyme inhibitors with hypoglycemic potentials amongst Eucalyptus Spp. by in vitro assays
Q57663817Extraction of free and insoluble-bound phenolic compounds from pigmented rice by commonly used procedures: a comparative study
Q58702014Food Byproducts as Sustainable Ingredients for Innovative and Healthy Dairy Foods
Q64934940Formononetin Treatment in Type 2 Diabetic Rats Reduces Insulin Resistance and Hyperglycemia.
Q33554311Fresh fruit consumption in relation to incident diabetes and diabetic vascular complications: A 7-y prospective study of 0.5 million Chinese adults
Q33759552Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review
Q38758858Gallic Acid Promotes Wound Healing in Normal and Hyperglucidic Conditions
Q47574640Gallic acid and p-coumaric acid attenuate type 2 diabetes-induced neurodegeneration in rats.
Q36707199Glucotoxicity Induced Oxidative Stress and Inflammation In Vivo and In Vitro in Psammomys obesus: Involvement of Aqueous Extract of Brassica rapa rapifera.
Q38708223Grapes (Vitis vinifera) as a Potential Candidate for the Therapy of the Metabolic Syndrome
Q95828462Healthy Eating Recommendations: Good for Reducing Dietary Contribution to the Body's Advanced Glycation/Lipoxidation End Products Pool?
Q37358926Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats
Q54986345Hypoglycaemic and Antioxidant Effects of Propolis of Chihuahua in a Model of Experimental Diabetes.
Q47159505Hypoglycemic, Hypolipidemic, and Wound Healing Potential of Quercetin in Streptozotocin-Induced Diabetic Rats
Q91639058Icariin treatment reduces blood glucose levels in type 2 diabetic rats and protects pancreatic function
Q39333401In vitro Metabolomic Approaches to Investigating the Potential Biological Effects of Phenolic Compounds: An Update
Q55498342In vitro and in vivo antidiabetic effect of extracts of Melia azedarach, Zanthoxylum alatum, and Tanacetum nubigenum.
Q38781272Influence of quercetin on the interaction of gliclazide with human serum albumin - spectroscopic and docking approaches.
Q91710089Islet Amyloid Polypeptide: A Partner in Crime With Aβ in the Pathology of Alzheimer's Disease
Q64989601Lupinus mutabilis Extract Exerts an Anti-Diabetic Effect by Improving Insulin Release in Type 2 Diabetic Goto-Kakizaki Rats.
Q90418355Mechanism of the action of bioactive proteins of vegetables in diabetes mellitus type 2: Systematic review protocol
Q48277155Modulation of Advanced Glycation End Products, Sorbitol, and Aldose Reductase by Hydroalcohol Extract of Lagenaria siceraria Mol Standl in Diabetic Complications: An In Vitro Approach
Q92084454Multicomponent Synthesis of Polyphenols and their in vitro Evaluation as Potential β-Amyloid Aggregation Inhibitors
Q48176641Murraya paniculata (L.) (Orange Jasmine): Potential Nutraceuticals with Ameliorative Effect in Alloxan-Induced Diabetic Rats.
Q92129314Natural Hydrogen Sulfide Donors from Allium sp. as a Nutraceutical Approach in Type 2 Diabetes Prevention and Therapy
Q38244247Natural polyphenols binding to amyloid: a broad class of compounds to treat different human amyloid diseases
Q39040955New insights into the antiangiogenic and proangiogenic properties of dietary polyphenols.
Q37168739Nutraceuticals against Neurodegeneration: A Mechanistic Insight
Q46880913Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, attenuates diabetes-induced renal damage through the advanced glycation end product-related pathway in db/db mice
Q38702685Olive Polyphenols and the Metabolic Syndrome.
Q64114899Peanut skin phenolic extract attenuates hyperglycemic responses in vivo and in vitro
Q26748605Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)
Q93110374Prosopis alba seed flour improves vascular function in a rabbit model of high fat diet-induced metabolic syndrome
Q35769224Protective Pleiotropic Effect of Flavonoids on NAD⁺ Levels in Endothelial Cells Exposed to High Glucose
Q50980737Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity.
Q40469443Reduction of Enteric Viruses by Blueberry Juice and Blueberry Proanthocyanidins.
Q28543472Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach
Q28393675Resveratrol protects against methylglyoxal-induced hyperglycemia and pancreatic damage in vivo
Q54841829Role of red grape polyphenols as antidiabetic agents.
Q33858968Significance of Microbiota in Obesity and Metabolic Diseases and the Modulatory Potential by Medicinal Plant and Food Ingredients
Q58562266Silver Fir (Abies alba) Extracts Inhibit Enzymes Involved in Blood Glucose Management and Protect against Oxidative Stress in High Glucose Environment
Q90231878Smallanthus sonchifolius (Yacon) Flour Improves Visceral Adiposity and Metabolic Parameters in High-Fat-Diet-Fed Rats
Q86422132The Antidiabetic and Antihypercholesterolemic Effects of an Aqueous Extract from Pecan Shells in Wistar Rats
Q26746903The Possible Role of Flavonoids in the Prevention of Diabetic Complications
Q90537220The Relationship Between Alcohol and Glycohemoglobin: A Biopsychosocial Perspective
Q38718497The Transcription Profile Unveils the Cardioprotective Effect of Aspalathin against Lipid Toxicity in an In Vitro H9c2 Model.
Q89684787The biology of ergothioneine, an antioxidant nutraceutical
Q92332819The effect of co supplementation of omega-3 and vitamin D on cardio metabolic risk factors and psychological distress in reproductive-aged women with prediabetes and hypovitaminosis D: a study protocol for a randomized controlled trial
Q26863346The effects of dietary polyphenols on reproductive health and early development
Q41195653Unfolding Novel Mechanisms of Polyphenol Flavonoids for Better Glycaemic Control: Targeting Pancreatic Islet Amyloid Polypeptide (IAPP).
Q90523235Wild Bilberry (Vaccinium myrtillus L., Ericaceae) from Montenegro as a Source of Antioxidants for Use in the Production of Nutraceuticals
Q36285113Wine Flavonoids in Health and Disease Prevention
Q33362165p-Coumaric acid and its conjugates: dietary sources, pharmacokinetic properties and biological activities

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