| P50 | author | Iwao Ojima | Q1676049 |
| P2093 | author name string | Iwao Ojima | |
| P2860 | cites work | Refined structure of alpha beta-tubulin at 3.5 A resolution | Q27636088 |
| | Fluorine in pharmaceuticals: looking beyond intuition | Q27648640 |
| | Structure of the alpha beta tubulin dimer by electron crystallography | Q27748784 |
| | Biotin | Q28026625 |
| | Multidrug resistance in cancer: role of ATP-dependent transporters | Q28208049 |
| | Biochemistry: biosynthesis of an organofluorine molecule | Q28208794 |
| | Therapeutic response of herpes simplex virus-induced corneal edema to trifluridine in combination with immunosuppressive agents | Q28303926 |
| | THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS | Q29308301 |
| | Disposition of docosahexaenoic acid-paclitaxel, a novel taxane, in blood: in vitro and clinical pharmacokinetic studies. | Q33185773 |
| | Survival of Mammals Breathing Organic Liquids Equilibrated with Oxygen at Atmospheric Pressure | Q33480168 |
| | Recent advances in the medicinal chemistry of taxoids with novel beta-amino acid side chains | Q33751126 |
| | Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR. | Q33886232 |
| | Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery. | Q33925595 |
| | Targeted delivery of chemotherapeutics: tumor-activated prodrug therapy | Q33933206 |
| | Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation | Q34001846 |
| | Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes | Q34065254 |
| | Crystal and molecular structure of paclitaxel (taxol). | Q34087570 |
| | Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids | Q34089278 |
| | The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man | Q34186254 |
| | A new class of angiotensin-converting enzyme inhibitors | Q34251984 |
| | Fluorine nuclear magnetic resonance, a privileged tool for metabolic studies of fluoropyrimidine drugs | Q34314635 |
| | Mechanism-based tumor-targeting drug delivery system. Validation of efficient vitamin receptor-mediated endocytosis and drug release. | Q34565264 |
| | Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo | Q34597483 |
| | Recent advances in the study of the bioactive conformation of taxol | Q34769728 |
| | On inventing reactions for atom economy | Q34861659 |
| | Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents | Q34936463 |
| | Antibody-drug conjugates: linking cytotoxic payloads to monoclonal antibodies. | Q35004254 |
| | Folate-targeted chemotherapy | Q35749880 |
| | Use of fluorine in the medicinal chemistry and chemical biology of bioactive compounds--a case study on fluorinated taxane anticancer agents | Q35762544 |
| | Tumor-targeting drug delivery of new-generation taxoids | Q35765100 |
| | Asymmetric synthesis of beta-lactams through the Staudinger reaction and their use as building blocks of natural and nonnatural products | Q35848119 |
| | Azetidin-2-ones, synthon for biologically important compounds | Q35848127 |
| | Beta-lactams as versatile synthetic intermediates for the preparation of heterocycles of biological interest | Q35848130 |
| | Dendrimers and dendritic polymers in drug delivery | Q36022312 |
| | n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. | Q36080066 |
| | Recent advances in tumor-targeting anticancer drug conjugates. | Q36162882 |
| | Uptake, localization, and noncarboxylase roles of biotin | Q36191087 |
| | Applications of carbon nanotubes in drug delivery | Q36289993 |
| | Antibody-cytotoxic agent conjugates for cancer therapy | Q36316831 |
| | Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids | Q36372764 |
| | Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations | Q36598611 |
| | Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy | Q36893212 |
| | Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads. | Q36896597 |
| | Functionalized carbon nanotubes in drug design and discovery | Q36941805 |
| | Molecular imaging with PET. | Q37143447 |
| | Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids | Q37193056 |
| | Design, synthesis, and biological evaluation of new-generation taxoids | Q37325768 |
| | pi-SCF-molecular mechanics PIMM: formulation, parameters, applications | Q37386275 |
| | Folate-Targeted Therapies for Cancer | Q37776257 |
| | The next generation of antibody-drug conjugates comes of age | Q37804936 |
| | Inactivation and metabolism of neuropeptides | Q38162555 |
| | A continuous spectrophotometric assay for angiotensin converting enzyme | Q40235334 |
| | Aptamer:toxin conjugates that specifically target prostate tumor cells | Q40267091 |
| | Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity | Q40328729 |
| | Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents | Q40349419 |
| | Use of the tubulin bound paclitaxel conformation for structure-based rational drug design | Q40441483 |
| | Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours | Q40509001 |
| | Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells | Q41166048 |
| | Promotion of microtubule assembly in vitro by taxol | Q41461193 |
| | Contributions of counter-charge in a potassium channel voltage-sensor domain. | Q42023842 |
| | Advances in the chemistry of β-lactam and its medicinal applications. | Q42095730 |
| | KNI-577, a potent small-sized HIV protease inhibitor based on the dipeptide containing the hydroxymethylcarbonyl isostere as an ideal transition-state mimic | Q42543158 |
| | Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere. | Q43507205 |
| | Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel | Q43763042 |
| | New strategy for the stereoselective synthesis of fluorinated beta-amino acids | Q44050526 |
| | The opioid activity and receptor selectivity of fluorinated Leu5 Enkephalin analogues in vitro and in vivo | Q44334119 |
| | Dietary intakes and food sources of omega-6 and omega-3 polyunsaturated fatty acids. | Q44504758 |
| | Accelerated metabolite identification by “Extraction-NMR” | Q44622481 |
| | Probing the proteolytic stability of beta-peptides containing alpha-fluoro- and alpha-hydroxy-beta-amino acids | Q44880172 |
| | Differential effect of fluorinated analogs of TRH on the cardiovascular system and prolactin release | Q48663913 |
| | Fluorinated tryptophans as substrates and inhibitors of the ATP-[32 P] PPi exchange reaction catalysed by tryptophanyl tRNA synthetase | Q57417518 |
| | Metabolism of new-generation taxanes in human, pig, minipig and rat liver microsomes | Q59183220 |
| | Tumor-Specific Novel Taxoid−Monoclonal Antibody Conjugates | Q59183296 |
| | Characterization of the Taxol Binding Site on the Microtubule | Q59183364 |
| | Synthesis and structure-activity relationships of new second-generation taxoids | Q59183369 |
| | Synthesis of novel 3'-trifluoromethyl taxoids through effective kinetic resolution of racemic 4-CF3-beta-lactams with baccatins | Q59183438 |
| | Design, synthesis and enzyme inhibitory activities of new trifluoromethyl-containing inhibitors for angiotensin converting enzyme | Q59183470 |
| | Design and synthesis of potent and specific renin inhibitors containing difluorostatine, difluorostatone, and related analogues | Q68902387 |
| | Aminoalkylphosphonofluoridate derivatives: rapid and potentially selective inactivators of serine peptidases | Q70826369 |
| | Mechanism for the antitumor and anticachectic effects of n-3 fatty acids | Q73034228 |
| | Phebestin, a new inhibitor of aminopeptidase N, produced by Streptomyces sp. MJ716-m3 | Q73147809 |
| | Glutathione concentration may be a useful predictor of response to second-line chemotherapy in patients with ovarian cancer | Q74226126 |
| | 4,5,6,7-Tetrafluorotryptophan: A substrate for tryptophan-tRNA ligase | Q77915575 |
| | Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles | Q84109228 |
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | fluorine | Q650 |
| P304 | page(s) | 6358-6383 | |
| P577 | publication date | 2013-05-06 | |
| P1433 | published in | Journal of Organic Chemistry | Q898967 |
| P1476 | title | Exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology | |
| P478 | volume | 78 | |