scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1146/ANNUREV.MED.48.1.353 |
P8608 | Fatcat ID | release_72zz4ewslnh63p2wmvje6ehb6e |
P3181 | OpenCitations bibliographic resource ID | 2051741 |
P698 | PubMed publication ID | 9046968 |
P5875 | ResearchGate publication ID | 14164193 |
P2093 | author name string | Eric K. Rowinsky, MD | |
P433 | issue | 1 | |
P921 | main subject | microtubule | Q189933 |
chemotherapy | Q974135 | ||
P304 | page(s) | 353-374 | |
P577 | publication date | 1997-02-01 | |
P1433 | published in | Annual Review of Medicine | Q567363 |
P1476 | title | THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS | |
P478 | volume | 48 |
Q35049068 | 4-Amino-5-benzoyl-2-(4-methoxyphenylamino)thiazole (DAT1): a cytotoxic agent towards cancer cells and a probe for tubulin-microtubule system. |
Q35683577 | 4. The natural products epothilones A and B as lead structures for anticancer drug discovery: chemistry, biology, and SAR studies |
Q49063865 | A Divergent Approach to the Marine Diterpenoids (+)-Dictyoxetane and (+)-Dolabellane V. |
Q47601795 | A Systems Biology Approach Provides Deeper Insights into Differentially Expressed Genes in Taxane-Anthracycline Chemoresistant and Non-Resistant Breast Cancers |
Q38561970 | A cell-based pharmacokinetics assay for evaluating tubulin-binding drugs |
Q36360764 | A critical review of lipid-based nanoparticles for taxane delivery |
Q37040640 | A leukotriene B4 receptor-2 is associated with paclitaxel resistance in MCF-7/DOX breast cancer cells |
Q39344829 | A novel C,D-spirolactone analogue of paclitaxel: autophagy instead of apoptosis as a previously unknown mechanism of cytotoxic action for taxoids |
Q33905704 | A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells |
Q43779746 | A preliminary pharmacokinetic study of docetaxel, carboplatin and concurrent radiotherapy for regionally advanced squamous cell carcinoma of the head and neck |
Q27006569 | A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics |
Q37560292 | A traditional poly herbal medicine "Le Pana Guliya" induces apoptosis in HepG2 and HeLa cells but not in CC1 cells: an in vitro assessment. |
Q34031434 | A tubulin binding peptide targets glioma cells disrupting their microtubules, blocking migration, and inducing apoptosis |
Q43773496 | Abundant expression of the microtubule-associated protein, ensconsin (E-MAP-115), alters the cellular response to Taxol |
Q35975007 | Advancements in the Treatment of Metastatic Breast Cancer (MBC): The Role of Ixabepilone |
Q37656206 | Advances in breast cancer treatment: the emerging role of ixabepilone |
Q38862820 | Advances in oral delivery of anti-cancer prodrugs |
Q42095730 | Advances in the chemistry of β-lactam and its medicinal applications. |
Q42934454 | Analysis of the protein expression changes during taxol-induced apoptosis under translation inhibition conditions. |
Q44651639 | Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L |
Q40046819 | Anti-microtubule activity of tubeimoside I and its colchicine binding site of tubulin |
Q36772390 | Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents |
Q34734079 | Anticancer drugs that induce cancer-associated cachectic syndromes |
Q39409812 | Antitumor activity and molecular dynamics simulations of paclitaxel-laden triazine dendrimers |
Q36694822 | Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft |
Q43844076 | Apoptosis induced by low-dose paclitaxel is associated with p53 upregulation in nasopharyngeal carcinoma cells |
Q40977884 | Bcl-2/Bcl-xL inhibitor ABT-737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel-induced cell death |
Q37804741 | Biologically active sesquiterpene coumarins fromFerulaspecies |
Q35496778 | Breast cancer medications and vision: effects of treatments for early-stage disease |
Q36925433 | Bridging converts a noncytotoxic nor-paclitaxel derivative to a cytotoxic analogue by constraining it to the T-Taxol conformation |
Q40493893 | CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line. |
Q28469491 | CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45 |
Q42833093 | Calpain inhibition stimulates caspase-dependent apoptosis induced by taxol in NIH3T3 cells. |
Q94550998 | Cancer and Alzheimer's disease inverse relationship: an age-associated diverging derailment of shared pathways |
Q51025634 | Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells. |
Q44101966 | Catalytic asymmetric three-component synthesis of homoallylic amines |
Q38935027 | Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic |
Q47812874 | Central Macular Thickness Monitoring after a Taxane-Based Therapy in Visually Asymptomatic Patients. |
Q33838951 | Centrosomal Protein 70 Is a Mediator of Paclitaxel Sensitivity |
Q34564374 | Chemistry and chemical biology of taxane anticancer agents. |
Q39659613 | Chemosensitization of human leukemia K562 cells to taxol by a Vanadium-salen complex |
Q26858839 | Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis |
Q45988720 | Cholic acid-based novel micellar nanoplatform for delivering FDA-approved taxanes. |
Q30670717 | Clinical and pharmacokinetic data of a docetaxel-epirubicin combination in metastatic breast cancer |
Q92052288 | Combined Modality Therapy Based on Hybrid Gold Nanostars Coated with Temperature Sensitive Liposomes to Overcome Paclitaxel-Resistance in Hepatic Carcinoma |
Q33728576 | Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells |
Q80510509 | Cyclin-dependent kinases as targets for cancer therapy |
Q81086253 | Cyclin-dependent kinases as targets for cancer therapy |
Q86493043 | Cytotoxic natural products from thai plants: a recent study |
Q92795542 | DHA-SBT-1214 Taxoid Nanoemulsion and Anti-PD-L1 Antibody Combination Therapy Enhances Antitumor Efficacy in a Syngeneic Pancreatic Adenocarcinoma Model |
Q56889252 | DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy |
Q34143291 | Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel |
Q54957223 | Design, Synthesis, and Biological Evaluations of Asymmetric Bow-Tie PAMAM Dendrimer-Based Conjugates for Tumor-Targeted Drug Delivery. |
Q37325768 | Design, synthesis, and biological evaluation of new-generation taxoids |
Q37329222 | Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids |
Q37549416 | Differential cell responses to nanoparticle docetaxel and small molecule docetaxel at a sub-therapeutic dose range. |
Q33752976 | Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization |
Q37825450 | Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives |
Q38542060 | Docetaxel and its potential in the treatment of refractory esophagogastric adenocarcinoma |
Q73432129 | Docetaxel in combination with epirubicin in metastatic breast cancer: pharmacokinetic interactions |
Q92447661 | Docetaxel-Loaded Disulfide Cross-Linked Nanoparticles Derived from Thiolated Sodium Alginate for Colon Cancer Drug Delivery |
Q36461825 | Docetaxel-loaded liposomes: preparation, pH sensitivity, pharmacokinetics, and tissue distribution |
Q46031139 | Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors. |
Q34143487 | Drug discovery targeting cell division proteins, microtubules and FtsZ. |
Q40850718 | Drug discovery: past, present and future. |
Q34273680 | Drug interactions of paclitaxel and docetaxel and their relevance for the design of combination therapy |
Q34535594 | Drug interactions of paclitaxel metabolism in human liver microsomes |
Q35849538 | Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011. |
Q39633767 | Effect of Mad2 on paclitaxel-induced cell death in ovarian cancer cells |
Q33560816 | Effect of spindle checkpoint on Akt2-mediated paclitaxel-resistance in A2780 ovarian cancer cells |
Q37628495 | Effects of 1,25(OH)₂D₃ on Cancer Cells and Potential Applications in Combination with Established and Putative Anti-Cancer Agents. |
Q61803676 | Effects of Piperazine Derivative on Paclitaxel Pharmacokinetics |
Q52123962 | Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis. |
Q45033397 | Effects of paclitaxel and docetaxel on EGFR-expressing human carcinoma cells under normoxic versus hypoxic conditions in vitro |
Q41773604 | Elevated prx1 provides resistance to docetaxel, but is not associated with predictive significance in lung cancer |
Q43867940 | Elimination of 118 Da: a characteristic fragmentation in the tandem mass spectra of 11(15 --> 1)-abeo-taxanes |
Q36758604 | Emerging therapeutic options for Philadelphia-positive acute lymphocytic leukemia |
Q59183374 | Enantiopure fluorine-containing taxoids: potent anticancer agents and versatile probes for biomedical problems |
Q35798402 | Encapsulation of docetaxel in oily core polyester nanocapsules intended for breast cancer therapy |
Q37021902 | Enhancement of paclitaxel-induced breast cancer cell death via the glycogen synthase kinase-3β-mediated B-cell lymphoma 2 regulation |
Q58696611 | Enhancing the Delivery of Chemotherapeutics: Role of Biodegradable Polymeric Nanoparticles |
Q33911979 | Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activity |
Q36979015 | Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues |
Q37118460 | Exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology. |
Q37673863 | Extracellular Vesicle-Mediated Reversal of Paclitaxel Resistance in Prostate Cancer. |
Q35091519 | Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies |
Q48176143 | Ferrocenyl Paclitaxel and Docetaxel Derivatives: Impact of an Organometallic Moiety on the Mode of Action of Taxanes. |
Q86403863 | Fibrates protect against vascular endothelial dysfunction induced by paclitaxel and carboplatin chemotherapy for cancer patients: a pilot study |
Q37074780 | Fluorine-Containing Taxoid Anticancer Agents and Their Tumor-Targeted Drug Delivery |
Q41630916 | Formation of complement-activating particles in aqueous solutions of Taxol: possible role in hypersensitivity reactions |
Q37687329 | Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway |
Q34908845 | Growth factor receptors and apoptosis regulators: signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer. |
Q34719865 | Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation |
Q35884220 | Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry. |
Q36648815 | IDN 5390: an oral taxane candidate for protracted treatment schedules |
Q89932847 | Identification of a lathyrane-type diterpenoid EM-E-11-4 as a novel paclitaxel resistance reversing agent with multiple mechanisms of action |
Q40599191 | Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells |
Q34155175 | Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen |
Q36642502 | Improved biochemical strategies for targeted delivery of taxoids |
Q93048585 | In Search of Panacea-Review of Recent Studies Concerning Nature-Derived Anticancer Agents |
Q39945309 | In vitro effect of radiation, antibody to epidermal growth factor receptor and Docetaxel in human head and neck squamous carcinoma cells with mutant P53 and over-expressed EGFR. |
Q36968133 | Induction and concurrent taxanes enhance both the pulmonary metabolic radiation response and the radiation pneumonitis response in patients with esophagus cancer |
Q35991706 | Inhibiting proliferation and enhancing chemosensitivity to taxanes in osteosarcoma cells by RNA interference-mediated downregulation of stathmin expression |
Q52955249 | Inhibition of human vascular endothelial cell migration and capillary-like tube formation by the microtubule-stabilizing agent peloruside A. |
Q34515624 | Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells |
Q36558125 | Inhibitors of mitotic kinesins: next-generation antimitotics |
Q27321017 | Integrin-linked kinase regulates interphase and mitotic microtubule dynamics |
Q36736349 | Investigational agents against platinum-resistant ovarian cancer |
Q44879452 | Isolation, identification, semi-synthesis of aziditaxel derivatives and their biological evaluation |
Q34418413 | Ixabepilone: a new treatment option for the management of taxane-resistant metastatic breast cancer |
Q34313121 | JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells |
Q73504342 | Late apoptotic effects of taxanes on K562 erythroleukemia cells: apoptosis is delayed upstream of caspase-3 activation |
Q33687982 | Liposomes, micelles and microemulsions as new delivery systems for cytotoxic alkaloids. |
Q54921747 | Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture. |
Q40431663 | Lyophilized paclitaxel magnetoliposomes as a potential drug delivery system for breast carcinoma via parenteral administration: in vitro and in vivo studies |
Q46042101 | Mechanisms of inhibition of endothelial cell migration by taxanes |
Q36214179 | MiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo |
Q34501681 | MiR-634 sensitizes nasopharyngeal carcinoma cells to paclitaxel and inhibits cell growth both in vitro and in vivo |
Q48297603 | Microtubule Dynamicity Is More Important than Stability in Memory Formation: an In Vivo Study |
Q49653378 | Microtubule-Actin Crosslinking Factor 1 and Plakins as Therapeutic Drug Targets |
Q39459854 | Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity |
Q35181795 | Microtubule-interacting drugs for cancer treatment |
Q34318072 | Microtubule-stabilizing agents: a growing class of important anticancer drugs |
Q40470308 | Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells. |
Q43437349 | Molecular cytogenetic evaluation of the mechanism of genotoxic potential of amsacrine and nocodazole in mouse bone marrow cells |
Q42731418 | Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site |
Q74539124 | Monoclonal antibodies to taxanes that neutralize the biological activity of paclitaxel |
Q30375438 | Multiparametric monitoring of chemotherapy treatment response in locally advanced breast cancer using quantitative ultrasound and diffuse optical spectroscopy |
Q47929908 | Nanoemulsion formulation of a novel taxoid DHA-SBT-1214 inhibits prostate cancer stem cell-induced tumor growth. |
Q57973339 | Natural products with taxol-like anti-tumor activity: Synthetic approaches to eleutherobin and dictyostatin |
Q64095791 | Network Pharmacology-Based identification of pharmacological mechanism of SQFZ injection in combination with Docetaxel on lung cancer |
Q30491925 | Non-toxic melanoma therapy by a novel tubulin-binding agent |
Q28481583 | Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53 |
Q38985034 | Novel antitumour indole alkaloid, Jerantinine A, evokes potent G2/M cell cycle arrest targeting microtubules |
Q28279384 | Novel cytotoxic agents: epothilones |
Q34432179 | Novel molecules that interact with microtubules and have functional activity similar to Taxol |
Q39012277 | Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism |
Q35207632 | Novel therapeutic agents under investigation for malignant melanoma |
Q54441195 | Open-label, randomized, single-dose, crossover study to evaluate the pharmacokinetics and safety differences between two docetaxel products, CKD-810 and Taxotere injection, in patients with advanced solid cancer. |
Q39329443 | Optimization of parameters for preparation of docetaxel-loaded PLGA nanoparticles by nanoprecipitation method |
Q37327639 | PPMP, a novel tubulin-depolymerizing agent against esophageal cancer in patient-derived tumor xenografts |
Q40657105 | PSK-mediated NF-kappaB inhibition augments docetaxel-induced apoptosis in human pancreatic cancer cells NOR-P1. |
Q83760900 | Paclitaxel as second-line chemotherapy in patients with gemcitabine-refractory pancreatic cancer: a retrospective study |
Q35166688 | Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy |
Q39160733 | Paclitaxel nanosuspensions for targeted chemotherapy - nanosuspension preparation, characterization, and use. |
Q35623627 | Paclitaxel-based chemotherapy for advanced pancreatic cancer after gemcitabine-based therapy failure: a case series of 5 patients |
Q36487089 | Paclitaxel-carboplatin combination chemotherapy in advanced breast cancer: accumulating evidence for synergy, efficacy, and safety |
Q33947088 | Paclitaxel-induced cell death: where the cell cycle and apoptosis come together |
Q38363629 | Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine |
Q27691306 | Paclitaxel: new uses for an old drug |
Q33857714 | Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis |
Q38791215 | Pharmacogenomics of second-line drugs used for treatment of unresponsive or relapsed osteosarcoma patients. |
Q28742710 | Pharmacokinetics, efficacy, and safety evaluation of docetaxel/hydroxypropyl-sulfobutyl-β-cyclodextrin inclusion complex |
Q37398150 | Phase I dose escalation study of KOS-1584, a novel epothilone, in patients with advanced solid tumors |
Q51483995 | Phase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors. |
Q39924170 | Phenethyl isothiocyanate induces cell cycle arrest and reduction of alpha- and beta-tubulin isotypes in human prostate cancer cells |
Q92782799 | Phytochemical Analysis, Biochemical and Mineral Composition and GC-MS Profiling of Methanolic Extract of Chinese Arrowhead Sagittaria trifolia L. from Northeast China |
Q36520778 | Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation. |
Q43496569 | Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity |
Q44558863 | Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel |
Q34702599 | Preparation, pharmacokinetics, biodistribution, antitumor efficacy and safety of Lx2-32c-containing liposome |
Q52690917 | Quest for Efficacious Next-Generation Taxoid Anticancer Agents and Their Tumor-Targeted Delivery. |
Q38931722 | Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents |
Q33967932 | Recent advances in cancer chemotherapy |
Q37400110 | Recent advances in the chemistry and biology of new generation taxoids |
Q34769728 | Recent advances in the study of the bioactive conformation of taxol |
Q27010654 | Recent progress in the development of polysaccharide conjugates of docetaxel and paclitaxel |
Q90183783 | Recent progress in the strategic incorporation of fluorine into medicinally active compounds |
Q36877796 | Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy. |
Q36001079 | Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation |
Q40793437 | Role of cytochrome P450 2C8*3 (CYP2C8*3) in paclitaxel metabolism and paclitaxel-induced neurotoxicity. |
Q39115898 | Role of tumor necrosis factor alpha-induced protein 1 in paclitaxel resistance. |
Q34001846 | Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation |
Q38408578 | SH003 enhances paclitaxel chemosensitivity in MCF-7/PAX breast cancer cells through inhibition of MDR1 activity |
Q37327246 | STI571 sensitizes breast cancer cells to 5-fluorouracil, cisplatin and camptothecin in a cell type-specific manner |
Q36365126 | Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors |
Q46704730 | Seventy-two-hour stability of Taxol in 5% dextrose or 0.9% sodium chloride in Viaflo, Freeflex, Ecoflac and Macoflex N non-PVC bags |
Q39093086 | Spiro-bicyclo[2.2.2]octane derivatives as paclitaxel mimetics. Synthesis and toxicity evaluation in breast cancer cell lines. |
Q38694536 | Strategic Incorporation of Fluorine into Taxoid Anticancer Agents for Medicinal Chemistry and Chemical Biology Studies |
Q27690134 | Structural investigations into the stereochemistry and activity of a phenylalanine-2,3-aminomutase from Taxus chinensis |
Q39138838 | Structural significance of the acyl group at the C-10 position and the A ring of the taxane core of paclitaxel for inducing nitric oxide and tumor necrosis factor production by murine macrophages |
Q38090681 | Structural studies of taxol analogues for drug discovery. |
Q44466661 | Structure-activity relationship study of taxoids for their ability to activate murine macrophages as well as inhibit the growth of macrophage-like cells |
Q80067067 | Structure-activity relationships in side-chain-modified epothilone analogues--how important is the position of the nitrogen atom? |
Q73980264 | Structure-activity relationships study at the 3'-N position of paclitaxel. Part 2: synthesis and biological evaluation of 3'-N-thiourea- and 3'-N-thiocarbamate-bearing paclitaxel analogues |
Q35168819 | Synergistic antimicrotubule therapy for prostate cancer |
Q37193056 | Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids |
Q57607834 | Synthesis and Biological Activity of C-6 and C-7 Modified Paclitaxels |
Q36372764 | Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids |
Q31988187 | Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel |
Q57607835 | Synthesis and biological activity of a novel C4–C6 bridged paclitaxel analog |
Q57607837 | Synthesis and biological evaluation of C-1 and ring modified A-norpaclitaxels |
Q44892653 | Synthesis and biological evaluation of C-3'NH/C-10 and C-2/C-10 modified paclitaxel analogues. |
Q54025270 | Synthesis and biological evaluation of highly potent analogues of epothilones B and D. |
Q44006404 | Synthesis and cytotoxicity of 2alpha-amido docetaxel analogues |
Q57607845 | Synthesis of 6α-hydroxypaclitaxel, the major human metabolite of paclitaxel |
Q81801304 | Synthesis, antiproliferative evaluation, and structure-activity relationships of 3-arylquinolines |
Q37093119 | TLR4 is a novel determinant of the response to paclitaxel in breast cancer |
Q37623838 | Targeting microtubules by natural agents for cancer therapy |
Q37030872 | Targeting synuclein-gamma to counteract drug resistance in cancer |
Q45759415 | Taxane-Induced Peripheral Neurotoxicity. |
Q36012041 | Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis |
Q33630392 | Taxol biosynthesis and molecular genetics |
Q24657911 | Taxol suppresses dynamics of individual microtubules in living human tumor cells |
Q48111623 | The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells |
Q37165362 | The ClC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis |
Q42852896 | The Effect of Adjuvant Dimethylenastron, a Mitotic Kinesin Eg5 Inhibitor, in Experimental Glaucoma Filtration Surgery |
Q24291382 | The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death |
Q91741269 | The Preparation, Determination of a Flexible Complex Liposome Co-Loaded with Cabazitaxel and β-Elemene, and Animal Pharmacodynamics on Paclitaxel-Resistant Lung Adenocarcinoma |
Q36752835 | The chemistry and biology of epothilones--the wheel keeps turning. |
Q37543912 | The epothilones: how pharmacology relates to clinical utility |
Q43743125 | The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies |
Q34720419 | The role of mitosis in LDL transport through cultured endothelial cell monolayers |
Q35774565 | The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase |
Q35103643 | The war on cancer: a report from the front lines |
Q28543507 | Thermosensitive and mucoadhesive sol-gel composites of paclitaxel/dimethyl-β-cyclodextrin for buccal delivery |
Q40340692 | Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition |
Q37267400 | Total synthesis and selective activity of a new class of conformationally restrained epothilones |
Q35101412 | Toxic optic neuropathy in the setting of docetaxel chemotherapy: a case report |
Q42824843 | Translation regulation after taxol treatment in NIH3T3 cells involves the elongation factor (eEF)2. |
Q39303893 | Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells |
Q36967160 | Treatment of acute lymphoblastic leukaemia : a new era. |
Q35130026 | Unconventional Motoring: An Overview of the Kin C and Kin I Kinesins |
Q35762544 | Use of fluorine in the medicinal chemistry and chemical biology of bioactive compounds--a case study on fluorinated taxane anticancer agents |
Q92592813 | YAP/TAZ Signaling and Resistance to Cancer Therapy |
Q39966639 | shRNA-targeted cyclooxygenase (COX)-2 inhibits proliferation, reduces invasion and enhances chemosensitivity in laryngeal carcinoma cells |
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