Phase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors.

scientific article published on 5 December 2006

Phase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10637-006-9027-2
P698PubMed publication ID17146730

P2093author name stringBeijnen JH
Schellens JH
Voest EE
Witteveen PO
Daehling A
Kuppens IE
Schot M
Schuessler VM
P2860cites workChemotherapeutic neuropathyQ33790285
Mechanism of action of antitumor drugs that interact with microtubules and tubulinQ34188643
Past and future of the mitotic spindle as an oncology targetQ34441105
Neurotoxicity of antineoplastic agentsQ40847058
Clinical characteristics of severe peripheral neuropathy induced by docetaxel (Taxotere).Q42550306
Motor neuropathy due to docetaxel and paclitaxelQ42555288
Quantitative analysis of D-24851, a novel anticancer agent, in human plasma and urine by liquid chromatography coupled with tandem mass spectrometryQ44951077
Role of taxanes in lung-cancer chemotherapyQ77420410
THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTSQ29308301
D-24851, a novel synthetic microtubule inhibitor, exerts curative antitumoral activity in vivo, shows efficacy toward multidrug-resistant tumor cells, and lacks neurotoxicityQ31983554
Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell deathQ33539855
P433issue3
P921main subjectpharmacokineticsQ323936
phase I clinical trialQ5452194
P304page(s)227-235
P577publication date2006-12-05
P1433published inInvestigational New DrugsQ2312231
P1476titlePhase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors.
P478volume25