scholarly article | Q13442814 |
P50 | author | Maria A Blasco | Q54086437 |
P2093 | author name string | Madalena Tarsounas | |
Maria Thanasoula | |||
Paula Martinez | |||
Jose Miguel Escandell | |||
Sophie Badie | |||
Purificacion Muñoz | |||
P2860 | cites work | Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells | Q21146367 |
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair | Q24299313 | ||
RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation | Q24311792 | ||
Telomere maintenance requires the RAD51D recombination/repair protein | Q24338140 | ||
TRF2 Protects Human Telomeres from End-to-End Fusions | Q28111898 | ||
Cell-cycle checkpoints and cancer | Q28293996 | ||
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 | Q28609749 | ||
Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
DNA damage foci at dysfunctional telomeres | Q29614811 | ||
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM | Q29614843 | ||
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
How shelterin protects mammalian telomeres | Q29615744 | ||
A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
Tumor spectrum analysis in p53-mutant mice | Q29617436 | ||
Radiation-induced cell cycle arrest compromised by p21 deficiency | Q29620237 | ||
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle | Q33227804 | ||
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. | Q33889383 | ||
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres | Q33890968 | ||
Regulation of the G2/M transition by p53. | Q33943437 | ||
Connecting chromosomes, crisis, and cancer | Q34141381 | ||
Phosphorylation of H2AX at short telomeres in T cells and fibroblasts | Q34550319 | ||
High-throughput telomere length quantification by FISH and its application to human population studies | Q34609809 | ||
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice | Q34997279 | ||
DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres | Q35837052 | ||
Functional links between telomeres and proteins of the DNA-damage response | Q35853775 | ||
gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes | Q36418967 | ||
Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. | Q40674805 | ||
Induction of senescence by oncogenic Ras. | Q40800050 | ||
Intact G2-phase checkpoint in cells of a human cell line lacking DNA-dependent protein kinase activity. | Q41125546 | ||
XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. | Q55041190 | ||
53BP1, an activator of ATM in response to DNA damage | Q64388924 | ||
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest | Q74355482 | ||
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres | Q79365400 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 521-526 | |
P577 | publication date | 2010-03-11 | |
P1433 | published in | Current Biology | Q1144851 |
P1476 | title | p53 prevents entry into mitosis with uncapped telomeres | |
P478 | volume | 20 |
Q35894239 | 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response |
Q36494808 | A three-state model of telomere control over human proliferative boundaries |
Q28387570 | ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres |
Q48007327 | Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes |
Q35116646 | BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres |
Q28115349 | BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping |
Q28594209 | CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion |
Q28475293 | Chromosome Tips Damaged in Anaphase Inhibit Cytokinesis |
Q61799774 | Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples |
Q34300546 | Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis. |
Q41894182 | Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres. |
Q34044618 | DNA damage to a single chromosome end delays anaphase onset |
Q93111214 | Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives |
Q33942627 | Effects of age and heart failure on human cardiac stem cell function |
Q42166975 | Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. |
Q34248736 | Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations |
Q34445264 | Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis. |
Q37668369 | Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation |
Q34142564 | IL-7Rα deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis |
Q46234448 | In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay. |
Q35667156 | Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation |
Q37210618 | TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection |
Q89909105 | Telomere length and telomerase activity in osteoporosis and osteoarthritis |
Q37046752 | Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells. |
Q30845102 | The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response. |
Q47654278 | The small molecule AU14022 promotes colorectal cancer cell death via p53-mediated G2/M-phase arrest and mitochondria-mediated apoptosis. |
Q35904248 | Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage |
Q34420523 | Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status |
Q38930927 | γH2AX foci on apparently intact mitotic chromosomes: not signatures of misrejoining events but signals of unresolved DNA damage |
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