Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB

scientific article published on 21 January 2009

Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01824-08
P932PMC publication ID2655545
P698PubMed publication ID19158244

P50authorJun-ichirou YasunagaQ55270267
Jean-Marie PeloponeseQ55270727
P2093author name stringKuan-Teh Jeang
Koichi Watashi
Takao Kinjo
P2860cites workThe HTLV-1 Tax interactomeQ21093224
Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1Q24336250
The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1Q24533164
Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.Q24535558
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteinsQ24606249
Actinomycin and DNA transcriptionQ24612517
Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?Q24684898
The prolyl isomerase Pin1 in breast development and cancerQ24795560
The discovery of the first human retrovirus: HTLV-1 and HTLV-2Q24804470
A human peptidyl-prolyl isomerase essential for regulation of mitosisQ28117639
Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gammaQ28199322
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damageQ28208518
Phosphorylation-specific prolyl isomerization: is there an underlying theme?Q28248256
Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformationQ28257025
Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signalingQ28586249
Nuclear factor-kappaB in cancer development and progressionQ29547879
NF-kappaB in cancer: from innocent bystander to major culpritQ29614603
Activation of E2F-mediated transcription by human T-cell leukemia virus type I Tax protein in a p16(INK4A)-negative T-cell lineQ41012105
A human T-cell leukemia virus Tax variant incapable of activating NF-kappaB retains its immortalizing potential for primary T-lymphocytesQ41050877
Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypesQ41715443
PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivoQ41895077
The N-terminus of rodent and human MAD1 confers species-specific stringency to spindle assembly checkpoint.Q42808044
Pin1 acts catalytically to promote a conformational change in Cdc25.Q43628400
IGF-1 induces Pin1 expression in promoting cell cycle S-phase entryQ43851743
Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoproteinQ44199158
Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancerQ44305041
The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer.Q44618217
IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax proteinQ45747947
IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.Q45749335
The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic miceQ45839884
Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrestQ47900743
PIN1, the cell cycle and cancer.Q53561253
Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone.Q55067472
Coiled-coil motif as a structural basis for the interaction of HTLV type 1 Tax with cellular cofactors.Q55239893
Interactions between HTLV-I Tax and NF-kappa B/Rel proteins in T cells.Q55241101
Apoptosis induced by Actinomycin D, Camptothecin or Aphidicolin can occur in all phases of the cell cycleQ68213571
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphomaQ29615115
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinasesQ33797174
Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B.Q33944410
A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosisQ34047242
Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoproteinQ34244979
Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human seraQ34276501
Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma proteinQ34278817
PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cellsQ34283602
Discovery of HTLV-1, the first human retrovirus, its unique regulatory mechanisms, and insights into pathogenesisQ34450086
Molecular mechanisms of cellular transformation by HTLV-1 Tax.Q34450092
Cell cycle dysregulation by HTLV-I: role of the tax oncoproteinQ34486225
The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplicationQ34536941
Damaged DNA and miscounted chromosomes: human T cell leukemia virus type I tax oncoprotein and genetic lesions in transformed cellsQ34765185
Prevalent overexpression of prolyl isomerase Pin1 in human cancersQ35097986
Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax proteinQ35108002
Human T-cell leukemia virus type I and adult T-cell leukemiaQ35196605
The peptidyl-prolyl isomerase Pin1.Q35573742
Mechanisms of HTLV-1 transformationQ35880631
Evidence for cooperative transforming activity of the human pituitary tumor transforming gene and human T-cell leukemia virus type 1 Tax.Q35947596
Inflammation-associated cancer: NF-kappaB is the lynchpinQ36143426
Deregulation of cell-signaling pathways in HTLV-1 infectionQ36254870
Modulation of nuclear factor-kappaB by human T cell leukemia virus type 1 Tax protein: implications for oncogenesis and inflammationQ36487067
Phorbol esters modulate the phosphorylation of human T-cell leukemia virus type I TaxQ36650699
Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteinsQ36687133
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformationQ36769835
Centrosome and retroviruses: the dangerous liaisonsQ36791138
Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequenceQ36873450
Abundant synthesis of functional human T-cell leukemia virus type I p40x protein in eucaryotic cells by using a baculovirus expression vectorQ36885347
Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1.Q36933894
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and diseaseQ36945537
Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitroQ37686052
HTLV-1 Tax: centrosome amplification and cancerQ38253740
Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, JurkatQ40116365
Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.Q40381392
Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damageQ40407604
Tax deregulation of NF-kappaB2 p100 processing involves both beta-TrCP-dependent and -independent mechanismsQ40525571
Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitorsQ40765650
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
NF-κBQ411114
Human T-lymphotropic virus 1Q1280388
T-cell leukemiaQ7667895
P1104number of pages11
P304page(s)3238-3248
P577publication date2009-01-21
P1433published inJournal of VirologyQ1251128
P1476titlePeptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB
P478volume83

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cites work (P2860)
Q37470581HTLV gene regulation: because size matters, transcription is not enough
Q37802510HTLV-1 and Adult T-Cell Leukemia: Insights into Viral Transformation of Cells 30 Years After Virus Discovery
Q39263944HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells
Q37124047HTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4(+) T cells
Q60907586Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein
Q36147455Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy
Q35090534Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis
Q38156859Human T-lymphotropic virus proteins and post-translational modification pathways
Q45368177Identification of CD44 as a downstream target of noncanonical NF-κB pathway activated by human T-cell leukemia virus type 1-encoded Tax protein
Q28080937KSHV reactivation and novel implications of protein isomerization on lytic switch control
Q37374081NF-κB as a Target for Oncogenic Viruses
Q37891181Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease
Q33934864Peptidyl-prolyl isomerase Pin1 is a cellular factor required for hepatitis C virus propagation
Q39230419Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication.
Q42005266Pinning down viral proteins: a new prototype for virus-host cell interaction
Q26825421Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins
Q26774352Roles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related Diseases
Q35128946TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax.
Q39068717The cellular peptidyl-prolyl cis/trans isomerase Pin1 regulates reactivation of Kaposi's sarcoma-associated herpesvirus from latency
Q46853154The intricate interplay between RNA viruses and NF-κB.
Q38852028The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target
Q95310577The peptidyl-prolyl cis-trans isomerase Pin1 interacts with three early regulatory proteins of human cytomegalovirus
Q38939954The role of Pin1 in the development and treatment of cancer
Q35077552Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling

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