Lamellipodia and filopodia in metastasis and invasion

scientific article published on 07 April 2008

Lamellipodia and filopodia in metastasis and invasion is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2008.03.039
P698PubMed publication ID18396168
P5875ResearchGate publication ID5456859

P50authorLaura MacheskyQ21264247
P2860cites workDual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasisQ30480311
P433issue14
P407language of work or nameEnglishQ1860
P304page(s)2102-2111
P577publication date2008-04-07
P1433published inFEBS LettersQ1388051
P1476titleLamellipodia and filopodia in metastasis and invasion
P478volume582

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cites work (P2860)
Q34504538Aberrant expression of Arpin in human breast cancer and its clinical significance
Q36450022Aberrant glycogen synthase kinase 3β in the development of pancreatic cancer
Q34585992Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy
Q38072817Actin binding proteins: their ups and downs in metastatic life.
Q36581678Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells.
Q37260040An outlook on ovarian cancer and borderline ovarian tumors: focus on genomic and proteomic findings
Q37580348Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis
Q53113764Any route for melanoblasts to colonize the skin!
Q39620742Asymmetric cancer-cell filopodium growth induced by electric-fields in a microfluidic culture chip
Q24648113Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567
Q27680078CARMIL leading edge localization depends on a non-canonical PH domain and dimerization
Q35640979CRMP1 Inhibits Proliferation of Medulloblastoma and Is Regulated by HMGA1
Q28388282Caveolin-1 induces lamellipodia formation via an Akt-dependent pathway
Q39135444Cdc42 and p190RhoGAP activation by CCN2 regulates cell spreading and polarity and induces actin disassembly in migrating keratinocytes.
Q38083887Cellular and molecular mechanisms controlling the migration of melanocytes and melanoma cells
Q27316921Cortactin Phosphorylated by ERK1/2 Localizes to Sites of Dynamic Actin Regulation and Is Required for Carcinoma Lamellipodia Persistence
Q37229340Corticotropin Releasing Factor promotes breast cancer cell motility and invasiveness.
Q64075444Cx43-Associated Secretome and Interactome Reveal Synergistic Mechanisms for Glioma Migration and MMP3 Activation
Q33679678DRP5 is involved in cancer cell growth and predicts poor prognosis in human osteosarcoma
Q38793596Deguelin inhibits the migration and invasion of lung cancer A549 and H460 cells via regulating actin cytoskeleton rearrangement
Q35100236Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions
Q28391837Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo
Q30560102Dysregulation of ezrin phosphorylation prevents metastasis and alters cellular metabolism in osteosarcoma
Q35469410Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines.
Q47283163Elevated hydrostatic pressure enhances the motility and enlarges the size of the lung cancer cells through aquaporin upregulation mediated by caveolin-1 and ERK1/2 signaling
Q30755062Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport
Q54635876Expression of Abl interactor 1 and its prognostic significance in breast cancer: a tissue-array-based investigation.
Q30009175F-BAR family proteins, emerging regulators for cell membrane dynamic changes-from structure to human diseases
Q39558892Fascin, an actin-bundling protein, promotes breast cancer progression in vitro
Q93257727Filopodia play an important role in the trans-mesothelial migration of ovarian cancer cells
Q42735921Filopodial focal complexes direct adhesion and force generation towards filopodia outgrowth
Q57805468Forces drive basement membrane invasion in
Q84764244From branched networks of actin filaments to bundles
Q92425551Functional Validation of DownRegulated MicroRNAs in HeLa Cells Treated with Polyalthia longifolia Leaf Extract Using Different Microscopic Approaches: A Morphological Alteration-Based Validation
Q39080969Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling
Q26739711Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy
Q36618983Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis
Q35998040Hem‐1: Putting the “WAVE” into actin polymerization during an immune response
Q55058467Heparin co-factor II enhances cell motility and promotes metastasis in non-small cell lung cancer.
Q33872469Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination
Q39327309High level of WAVE1 expression is associated with tumor aggressiveness and unfavorable prognosis of epithelial ovarian cancer
Q35121121Hsp90 C-terminal inhibitors exhibit antimigratory activity by disrupting the Hsp90α/Aha1 complex in PC3-MM2 cells
Q36977402Hybrid liposomes inhibit tumor growth and lung metastasis of murine osteosarcoma cells.
Q54100467Identification of ARL4C as a Peritoneal Dissemination-Associated Gene and Its Clinical Significance in Gastric Cancer.
Q38433013Identification of oral cancer related candidate genes by integrating protein-protein interactions, gene ontology, pathway analysis and immunohistochemistry.
Q42724911In silico analysis of combinatorial microRNA activity reveals target genes and pathways associated with breast cancer metastasis.
Q35555982Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma
Q28655851Integrated cellular and gene interaction modelling of pattern formation
Q42128881Integrin acts upstream of netrin signaling to regulate formation of the anchor cell's invasive membrane in C. elegans
Q36171317Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion
Q49787431Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration
Q39332459Invadosomes are coming: new insights into function and disease relevance
Q36070908Involvement of DNMT 3B promotes epithelial-mesenchymal transition and gene expression profile of invasive head and neck squamous cell carcinomas cell lines
Q40821501Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion
Q36283431Liver X receptor regulates rheumatoid arthritis fibroblast-like synoviocyte invasiveness, matrix metalloproteinase 2 activation, interleukin-6 and CXCL10.
Q30597743Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells
Q27331969Loss of myoferlin redirects breast cancer cell motility towards collective migration
Q39584472MDA-9/syntenin interacts with ubiquitin via a novel ubiquitin-binding motif.
Q30366227MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells.
Q39156200Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity
Q30633015Mechanical interplay between invadopodia and the nucleus in cultured cancer cells
Q55265662Mechanisms of Aquaporin-Facilitated Cancer Invasion and Metastasis.
Q33895232Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
Q39137490Morphological effects of autologous hsp70 on peritoneal macrophages in a murine T cell lymphoma
Q34288205Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.
Q92736081Mutant p53 on the Path to Metastasis
Q99202201NF1-RAC1 axis regulates migration of the melanocytic lineage
Q36950646New roles for endosomes: from vesicular carriers to multi-purpose platforms
Q28550876Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases
Q28385469Ouabain suppresses the migratory behavior of lung cancer cells
Q33564546Overexpression of HER2 signaling to WAVE2-Arp2/3 complex activates MMP-independent migration in breast cancer
Q35176391Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility.
Q90610987PRR14 overexpression promotes cell growth, epithelial to mesenchymal transition and metastasis of colon cancer via the AKT pathway
Q97681270Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells
Q47136871Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin αv and integrin β3.
Q37746085Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors
Q33761889Polyisoprenylated cysteinyl amide inhibitors disrupt actin cytoskeleton organization, induce cell rounding and block migration of non-small cell lung cancer
Q24304683Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase
Q30585662Protrusion fluctuations direct cell motion
Q30525522Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression
Q36651370Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells
Q36702577Regulation of directional cell migration by membrane-induced actin bundling
Q39588446Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors
Q54984579Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing.
Q39494666Sdc1 negatively modulates carcinoma cell motility and invasion
Q47100968Selenium nanoparticles induce suppressed function of tumor associated macrophages and inhibit Dalton's lymphoma proliferation
Q54531699Serum- and glucocorticoid-dependent kinase-1-induced cell migration is dependent on vinculin and regulated by the membrane androgen receptor.
Q35578598Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway
Q35770840Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers
Q30415151Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes
Q39490653Src-stimulated IRTKS phosphorylation enhances cell migration
Q92561858Stretching cells - An approach for early cancer diagnosis
Q48160145Substrate rigidity-dependent positive feedback regulation between YAP and ROCK2.
Q35781480Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells
Q93075261The Combined Effects of Co-Culture and Substrate Mechanics on 3D Tumor Spheroid Formation within Microgels Prepared via Flow-Focusing Microfluidic Fabrication
Q24308702The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration
Q52629081The Role of Actin Dynamics and Actin-Binding Proteins Expression in Epithelial-to-Mesenchymal Transition and Its Association with Cancer Progression and Evaluation of Possible Therapeutic Targets.
Q39066567The Role of BAR Domain Proteins in the Regulation of Membrane Dynamics
Q35964611The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer
Q42011176The cell ratchet: interplay between efficient protrusions and adhesion determines cell motion
Q57288777The chemosensory function of primary cilia regulates cholangiocyte migration, invasion and tumor growth
Q30010241The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading
Q41694358The inhibitory effect of 7,7″-dimethoxyagastisflavone on the metastasis of melanoma cells via the suppression of F-actin polymerization
Q35556999The role of actin bundling proteins in the assembly of filopodia in epithelial cells
Q28577203The vitamin D receptor regulates rheumatoid arthritis synovial fibroblast invasion and morphology
Q52948746Tumor cells interact with red blood cells via galectin-4 - a short report.
Q57301415Various stem cells in acupuncture meridians and points and their putative roles
Q30944807Virus movements on the plasma membrane support infection and transmission between cells
Q27318774Visualization of phosphatidic acid fluctuations in the plasma membrane of living cells
Q39151090WAVE1 gene silencing via RNA interference reduces ovarian cancer cell invasion, migration and proliferation
Q30489687Wash functions downstream of Rho and links linear and branched actin nucleation factors
Q31036801Wavelet-based multiscale analysis of bioimpedance data measured by electric cell-substrate impedance sensing for classification of cancerous and normal cells.
Q35088197Weak power frequency magnetic field acting similarly to EGF stimulation, induces acute activations of the EGFR sensitive actin cytoskeleton motility in human amniotic cells
Q33815708c-Src differentially regulates the functions of microtentacles and invadopodia.
Q34112686mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis
Q46142063miR-206 Inhibits Stemness and Metastasis of Breast Cancer by Targeting MKL1/IL11 Pathway.
Q38877448γ-Synuclein confers both pro-invasive and doxorubicin-mediated pro-apoptotic properties to the colon adenocarcinoma LS 174T cell line.

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