NF1-RAC1 axis regulates migration of the melanocytic lineage

scientific article published on 03 September 2020

NF1-RAC1 axis regulates migration of the melanocytic lineage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TRANON.2020.100858
P932PMC publication ID7484592
P698PubMed publication ID32891903

P2093author name stringHeike Allgayer
Jochen Utikal
Lionel Larribère
Nitin Patil
Mohammed Abba
Isabel Tundidor
Rubén Gerardo Aguiñón Olivares
Yohanes Cakrapradipta Wibowo
P2860cites workExome sequencing identifies recurrent somatic RAC1 mutations in melanomaQ24607661
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Neurofibromatosis type 1 gene product (neurofibromin) associates with microtubulesQ28260637
RHO-GTPases and cancerQ29616099
P-Rex1 is required for efficient melanoblast migration and melanoma metastasisQ34235334
NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar developmentQ34430736
The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway.Q34451888
Genomic Classification of Cutaneous MelanomaQ34670776
Angiotropism, pericytic mimicry and extravascular migratory metastasis in melanoma: an alternative to intravascular cancer disseminationQ34766649
Syndecan-2 induces filopodia and dendritic spine formation via the neurofibromin-PKA-Ena/VASP pathwayQ36118445
Metastasis suppressor genes: from gene identification to protein function and regulationQ36219149
Lamellipodia and filopodia in metastasis and invasionQ37132020
Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.Q37348865
Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesisQ38327730
The pre-GAP-related domain of neurofibromin regulates cell migration through the LIM kinase/cofilin pathwayQ38351627
The front and rear of collective cell migration.Q38685677
Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells.Q38797046
Multiple roles of NF1 in the melanocyte lineageQ38828126
STAT3 and HIF1α Signaling Drives Oncogenic Cellular Phenotypes in Malignant Peripheral Nerve Sheath Tumors.Q38891950
NF1-mutated melanoma tumors harbor distinct clinical and biological characteristicsQ38925098
The NF1 gene in tumor syndromes and melanomaQ39076849
Targeting invasive properties of melanoma cells.Q39135139
Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinaseQ39845497
TaqMan-based quantification of invasive cells in the chick embryo metastasis assay.Q40480967
The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responsesQ42498482
Differential effects of neurofibromin gene dosage on melanocyte developmentQ44718557
Rho-GTPase signaling drives melanoma cell plasticityQ47994759
NF1 loss induces senescence during human melanocyte differentiation in an iPSC-based modelQ49150464
Diminished levels of the soluble form of RAGE are related to poor survival in malignant melanoma.Q53490356
Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma.Q53777162
Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells.Q53802002
Targeted Therapy-Resistant Melanoma Cells Acquire Transcriptomic Similarities with Human MelanoblastsQ59797793
Expression of Neural Crest Markers GLDC and ERRFI1 is Correlated with Melanoma PrognosisQ61795891
Neurofibromin as a regulator of melanocyte development and differentiationQ80224090
Gene expression profiling of human angiotropic primary melanoma: selection of 15 differentially expressed genes potentially involved in extravascular migratory metastasisQ83446206
P433issue12
P304page(s)100858
P577publication date2020-09-03
P1433published inTranslational OncologyQ26839583
P1476titleNF1-RAC1 axis regulates migration of the melanocytic lineage
P478volume13

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