| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2009PNAS..106.4360F |
| P356 | DOI | 10.1073/PNAS.0811332106 |
| P8608 | Fatcat ID | release_4b6kznpyczfrpkryi5yd4q7upi |
| P932 | PMC publication ID | 2657451 |
| P698 | PubMed publication ID | 19255426 |
| P5875 | ResearchGate publication ID | 24171785 |
| P50 | author | Cornelia Weyand | Q87638981 |
| P2093 | author name string | Inés Colmegna | |
| Lan Shao | |||
| Jörg J Goronzy | |||
| Hiroshi Fujii | |||
| P2860 | cites work | Extension of life-span by introduction of telomerase into normal human cells | Q24336088 |
| Telomere measurement by quantitative PCR | Q24529938 | ||
| Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita | Q24536887 | ||
| Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation | Q24797866 | ||
| DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
| The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Q28189076 | ||
| Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester | Q28248444 | ||
| Shelterin: the protein complex that shapes and safeguards human telomeres | Q28272546 | ||
| Switching and signaling at the telomere | Q29615653 | ||
| Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis | Q33646411 | ||
| Telomerase reverse-transcriptase homozygous mutations in autosomal recessive dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome | Q33899947 | ||
| Telomeres and their control | Q34090772 | ||
| Ectopic lymphoid organogenesis: a fast track for autoimmunity | Q34363840 | ||
| Phosphorylation of H2AX at short telomeres in T cells and fibroblasts | Q34550319 | ||
| Telomeres and aging | Q34768068 | ||
| Telomeres in T and B cells | Q34810292 | ||
| Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study | Q34923104 | ||
| T cell homeostasis in patients with rheumatoid arthritis | Q35200330 | ||
| p53-dependent integration of telomere and growth factor deprivation signals | Q35721430 | ||
| Telomere erosion: a new link between HLA DR4 and rheumatoid arthritis? | Q35810876 | ||
| Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT. | Q35847856 | ||
| TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque | Q36227892 | ||
| Regulated expression of telomerase activity in human T lymphocyte development and activation | Q36366852 | ||
| T cell activation as starter and motor of rheumatic inflammation. | Q36489100 | ||
| The role of DNA damage response proteins at telomeres--an "integrative" model | Q36517753 | ||
| Telomeres: cancer to human aging | Q36528826 | ||
| T-cell-targeted therapies in rheumatoid arthritis | Q36577464 | ||
| Therapy Insight: managing cardiovascular risk in patients with rheumatoid arthritis | Q36577503 | ||
| Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. | Q37089409 | ||
| SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity | Q39698075 | ||
| Active and Suppressor T Cells: Diminution in a Patient with Dyskeratosis Congenita and in First-Degree Relatives | Q40715180 | ||
| Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28- T cells from rheumatoid arthritis patients | Q41024041 | ||
| Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo | Q41945126 | ||
| Association of immune abnormalities with telomere shortening in autosomal-dominant dyskeratosis congenita | Q42464223 | ||
| Mechanism of telomerase induction during T cell activation | Q44208409 | ||
| Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection. | Q45721841 | ||
| The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation. | Q51974710 | ||
| T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. | Q51983441 | ||
| Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27. | Q51987403 | ||
| Will telomere erosion lead to a loss of T-cell memory? | Q51998145 | ||
| Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. | Q52018513 | ||
| Telomerase levels control the lifespan of human T lymphocytes | Q60628793 | ||
| Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis | Q60628794 | ||
| Dyskeratosis congenita | Q79843707 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | rheumatoid arthritis | Q187255 |
| P304 | page(s) | 4360-4365 | |
| P577 | publication date | 2009-03-02 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Telomerase insufficiency in rheumatoid arthritis | |
| P478 | volume | 106 |
| Q90216608 | Abnormal numbers of CD4+ T lymphocytes and abnormal expression of CD4+ T lymphocyte‑secreted cytokines in patients with immune‑related haemocytopenia |
| Q90446908 | Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression |
| Q37246355 | Age-related changes in arthritis susceptibility and severity in a murine model of rheumatoid arthritis |
| Q40398975 | Aging of the Immune System. Mechanisms and Therapeutic Targets |
| Q37681485 | Alterations in both the activatory and inhibitory potential of peripheral blood CD4+ T cells in rheumatoid arthritis patients correlate with disease progression |
| Q92208626 | Association of nutraceutical supplements with longer telomere length |
| Q35800364 | Autophagy in autoimmune disease |
| Q42220520 | Autophagy plays a protective role as an anti-oxidant system in human T cells and represents a novel strategy for induction of T-cell apoptosis. |
| Q36179565 | CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells |
| Q37801737 | Cell and cytokine imbalances in rheumatoid synovitis |
| Q37959331 | Cellular and molecular mechanisms of autoimmune disease |
| Q50424601 | Characterization in humans of in vitro leucocyte maximal telomerase activity capacity and association with stress |
| Q41471328 | Chronic Inflammation in Immune Aging: Role of Pattern Recognition Receptor Crosstalk with the Telomere Complex? |
| Q36176981 | Chronic inflammation and aging: DNA damage tips the balance |
| Q47443520 | DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system |
| Q34474734 | DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis |
| Q35830840 | Dampened ERK signaling in hematopoietic progenitor cells in rheumatoid arthritis |
| Q37273198 | Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis |
| Q42363315 | Deficient Activity of the Nuclease MRE11A Induces T Cell Aging and Promotes Arthritogenic Effector Functions in Patients with Rheumatoid Arthritis. |
| Q37454068 | Developments in the scientific understanding of rheumatoid arthritis |
| Q64885851 | Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions. |
| Q33686997 | ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis |
| Q58579018 | Effect of therapies-mediated modulation of telomere and/or telomerase on cancer cells radiosensitivity |
| Q37774304 | Epidemiology of rheumatoid arthritis: rheumatoid arthritis and mortality |
| Q90314188 | Expression and regulation of telomerase in human T cell differentiation, activation, aging and diseases |
| Q34506827 | Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies |
| Q35617577 | Giant cell arteritis: immune and vascular aging as disease risk factors |
| Q34495902 | Haematopoietic stem and progenitor cells in rheumatoid arthritis |
| Q34560012 | Healthy aging and disease: role for telomere biology? |
| Q36616642 | IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens |
| Q34777989 | Immune aging and autoimmunity |
| Q34036703 | Immune aging and rheumatoid arthritis |
| Q35059538 | Immunosenescence and rheumatoid arthritis: does telomere shortening predict impending disease? |
| Q37292111 | Immunosenescence, aging, and systemic lupus erythematous |
| Q90062620 | Inflammaging and Oxidative Stress in Human Diseases: From Molecular Mechanisms to Novel Treatments |
| Q58763477 | Inhibition of TRF2 accelerates telomere attrition and DNA damage in naïve CD4 T cells during HCV infection |
| Q52592808 | Insufficiency of DNA repair enzyme ATM promotes naive CD4 T-cell loss in chronic hepatitis C virus infection. |
| Q33582101 | Interleukin-7 and Immunosenescence. |
| Q36056599 | K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis |
| Q35880403 | Mechanisms of immunosenescence: lessons from models of accelerated immune aging |
| Q92914293 | Mechanisms of lung disease development in rheumatoid arthritis |
| Q34415999 | Methotrexate inhibits NF-κB activity via long intergenic (noncoding) RNA-p21 induction |
| Q34360195 | Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans |
| Q35674471 | Naive T cell maintenance and function in human aging |
| Q35136851 | Naive T-cells in myelodysplastic syndrome display intrinsic human telomerase reverse transcriptase (hTERT) deficiency. |
| Q38460545 | Neuroendocrine and viral correlates of premature immunosenescence |
| Q28298650 | Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells |
| Q39182224 | Progress in Human and Tetrahymena Telomerase Structure Determination |
| Q52663131 | Redox-sensitive signaling in inflammatory T cells and in autoimmune disease. |
| Q35025444 | Reduced T-cell repertoire restrictions in abatacept-treated rheumatoid arthritis patients |
| Q37607081 | Rejuvenating the immune system in rheumatoid arthritis |
| Q37357112 | Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis |
| Q37670307 | Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes |
| Q33555281 | Rheumatoid Arthritis, Immunosenescence and the Hallmarks of Aging |
| Q27693905 | Rheumatoid Arthritis: A Role for Immunosenescence? |
| Q38149252 | Rheumatoid arthritis and cardiovascular disease |
| Q93176410 | Stress and immunosenescence: The role of telomerase |
| Q39193878 | Successful and Maladaptive T Cell Aging |
| Q26859971 | T-cell aging in rheumatoid arthritis |
| Q36246006 | T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles |
| Q35071556 | T-cell metabolism in autoimmune disease |
| Q36160188 | Targets of immune regeneration in rheumatoid arthritis |
| Q34170012 | Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy |
| Q54174954 | Telomerase expression in individuals with chronic and aggressive periodontitis. |
| Q42385423 | Telomere Length and Coronary Atherosclerosis in Rheumatoid Arthritis |
| Q37203171 | Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects |
| Q35806766 | Telomere dysfunction, autoimmunity and aging. |
| Q57456657 | Telomere dysfunction-related serological markers and oxidative stress markers in rheumatoid arthritis patients: correlation with diseases activity |
| Q89909105 | Telomere length and telomerase activity in osteoporosis and osteoarthritis |
| Q40307232 | Telomere length in patients with pulmonary fibrosis associated with chronic lung allograft dysfunction and post-lung transplantation survival |
| Q38060615 | Telomere shortening and Alzheimer's disease. |
| Q34051060 | Telomeres and immunological diseases of aging |
| Q28077460 | The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect? |
| Q38107139 | The gracefully aging immune system |
| Q38115131 | The influence of ageing on the development and management of rheumatoid arthritis |
| Q36898613 | The janus head of T cell aging - autoimmunity and immunodeficiency |
| Q94518211 | The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females |
| Q34281329 | Understanding immunosenescence to improve responses to vaccines |
| Q38611147 | Vitamin D in rheumatoid arthritis-towards clinical application |
| Q41788396 | hTERT deficiency in naïve T cells affects lymphocyte homeostasis in myelodysplastic syndrome patients |
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