Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages.

scientific article published on 24 October 2003

Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2003PNAS..10013471S
P356DOI10.1073/PNAS.2233561100
P932PMC publication ID263838
P698PubMed publication ID14578453
P5875ResearchGate publication ID231589379

P50authorEwa BrylQ40689596
Stefan SchönlandQ47114671
Cornelia WeyandQ87638981
P2093author name stringJörg J Goronzy
Julia Zimmer
Thomas Widmann
Consuelo Lopez
P2860cites workCD4+CD28- costimulation-independent T cells in multiple sclerosisQ24670063
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Telomere length predicts replicative capacity of human fibroblastsQ29615745
CD4+,CD28- T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systemsQ32044990
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The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infectionQ33904114
Regulatory T cells: key controllers of immunologic self-toleranceQ33941140
Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritisQ34216833
Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritisQ34222528
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T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell poolQ34998720
T cell homeostasis in patients with rheumatoid arthritisQ35200330
Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".Q36362764
Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritisQ36368995
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.Q36375132
Perturbation of the T cell repertoire in rheumatoid arthritisQ36735976
CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivityQ37354502
Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hostsQ37463129
New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study.Q37486377
The Molecular Basis of Susceptibility to Rheumatoid ArthritisQ40392032
Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL.Q40822163
Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathwaysQ40841306
Lymphocyte homeostasisQ41665913
Restoration of T-cell homeostasis after T-cell depletionQ41665917
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the peripheryQ41690259
Major histocompatibility complex-directed susceptibility to rheumatoid arthritisQ41722145
Functional disruption of the CD28 gene transcriptional initiator in senescent T cellsQ42495629
Genetic determination of telomere size in humans: a twin study of three age groups.Q42558225
T-cell depletion of HLA-identical transplants in leukemia.Q43844182
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infectionQ44902494
Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humansQ46083258
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.Q46315215
Control of homeostasis of CD8+ memory T cells by opposing cytokines.Q52027383
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.Q52125555
Killer Cell Activating Receptors Function as Costimulatory Molecules on CD4+CD28null T Cells Clonally Expanded in Rheumatoid ArthritisQ56607491
Changes in thymic function with age and during the treatment of HIV infectionQ59066353
Thymic function and peripheral T-cell homeostasis in rheumatoid arthritisQ73807442
Dynamics of telomere shortening in neutrophils and T lymphocytes during ageing and the relationship to skewed X chromosome inactivation patternsQ73883371
Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognitionQ77879066
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
P304page(s)13471-13476
P577publication date2003-10-24
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePremature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages
P478volume100

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