Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other Alpha-proteobacteria

scientific article published on 18 December 2008

Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other Alpha-proteobacteria is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10534-008-9192-1
P8608Fatcat IDrelease_od2pdo3aojejhmklx2zn2qwcxq
P932PMC publication ID2659648
P698PubMed publication ID19093075
P5875ResearchGate publication ID23674079

P2093author name stringMark R O'Brian
Sumant Puri
Sandra K Small
P2860cites workIdentification of the ubiquitin-protein ligase that recognizes oxidized IRP2Q24297533
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CO-sensing mechanismsQ24562799
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Heme induces ubiquitination and degradation of the transcription factor Bach1Q24684849
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A Redox-controlled Molecular Switch Revealed by the Crystal Structure of a Bacterial Heme PAS SensorQ27643191
Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupiedQ27766478
Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressorsQ28488940
The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coliQ28493158
Fur functions as an activator and as a repressor of putative virulence genes in Neisseria meningitidisQ29346571
Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA.Q29346681
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulonQ29346686
Recognition of DNA by Fur: a reinterpretation of the Fur box consensus sequenceQ29346692
Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis.Q29346698
Recognition of DNA by three ferric uptake regulator (Fur) homologs in Bacillus subtilis.Q29346705
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genesQ29346768
Sinorhizobium meliloti fur-like (Mur) protein binds a fur box-like sequence present in the mntA promoter in a manganese-responsive mannerQ29346918
A novel DNA-binding site for the ferric uptake regulator (Fur) protein from Bradyrhizobium japonicumQ29347223
Bacterial iron homeostasisQ29615095
Protein oxidation in aging, disease, and oxidative stressQ29619442
Role of the regulatory gene rirA in the transcriptional response of Sinorhizobium meliloti to iron limitationQ30476299
Computational reconstruction of iron- and manganese-responsive transcriptional networks in alpha-proteobacteriaQ33266803
Bacterial solutions to the iron-supply problemQ33594207
OxyR and SoxRS regulation of furQ33635537
Opening the iron box: transcriptional metalloregulation by the Fur protein.Q33749138
Iron and oxidative stress in bacteriaQ33808433
OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteinsQ33855733
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clockQ33949726
Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ionsQ33955368
DNA microarray-mediated transcriptional profiling of the Escherichia coli response to hydrogen peroxideQ33996654
NPAS2: a gas-responsive transcription factorQ34160458
Iron and metal regulation in bacteriaQ34205005
The Iron control element, acting in positive and negative control of iron-regulated Bradyrhizobium japonicum genes, is a target for the Irr protein.Q34303284
A Salmonella enterica serovar typhimurium hemA mutant is highly susceptible to oxidative DNA damageQ34315068
Activation of the OxyR transcription factor by reversible disulfide bond formationQ34459806
Nur, a nickel-responsive regulator of the Fur family, regulates superoxide dismutases and nickel transport in Streptomyces coelicolorQ34504215
Bradyrhizobium japonicum senses iron through the status of haem to regulate iron homeostasis and metabolismQ34507192
Regulation of inducible peroxide stress responsesQ34722966
Metals control activity and expression of the heme biosynthesis enzyme delta-aminolevulinic acid dehydratase in Bradyrhizobium japonicumQ35629190
Transcriptional regulation of the heme binding protein gene family of Bartonella quintana is accomplished by a novel promoter element and iron response regulatorQ35947267
The N-end rule pathway is a sensor of hemeQ36423606
Signal transduction and transcriptional and posttranscriptional control of iron-regulated genes in bacteria.Q36574340
Heme is an effector molecule for iron-dependent degradation of the bacterial iron response regulator (Irr) protein.Q36665454
The Bradyrhizobium japonicum Irr protein is a transcriptional repressor with high-affinity DNA-binding activityQ36804418
KatG is the primary detoxifier of hydrogen peroxide produced by aerobic metabolism in Bradyrhizobium japonicumQ37623315
Identification and characterization of a new organic hydroperoxide resistance (ohr) gene with a novel pattern of oxidative stress regulation from Xanthomonas campestris pv. phaseoliQ39565991
Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.Q40394197
The Sinorhizobium meliloti fur gene regulates, with dependence on Mn(II), transcription of the sitABCD operon, encoding a metal-type transporterQ40883339
Fur is involved in manganese-dependent regulation of mntA (sitA) expression in Sinorhizobium meliloti.Q41031341
A novel heme-regulatory motif mediates heme-dependent degradation of the circadian factor period 2.Q41337613
Discovery of a haem uptake system in the soil bacterium Bradyrhizobium japonicumQ42658366
Reciprocal regulation of haem biosynthesis and the circadian clock in mammalsQ42827031
Identification of a heme-sensing domain in iron regulatory protein 2.Q45021725
Two heme binding sites are involved in the regulated degradation of the bacterial iron response regulator (Irr) protein.Q45197492
Identification and molecular analysis of oxyR-regulated promoters important for the bacterial adaptation to oxidative stressQ46451759
Computational identification of BioR, a transcriptional regulator of biotin metabolism in Alphaproteobacteria, and of its binding signal.Q46911110
The ferric uptake regulator (Fur) protein from Bradyrhizobium japonicum is an iron-responsive transcriptional repressor in vitroQ47590652
The Fur-like protein Mur of Rhizobium leguminosarum is a Mn(2+)-responsive transcriptional regulatorQ47632868
The dps promoter is activated by OxyR during growth and by IHF and σs in stationary phaseQ47673138
The bacterial irr protein is required for coordination of heme biosynthesis with iron availabilityQ47682305
A small, stable RNA induced by oxidative stress: role as a pleiotropic regulator and antimutatorQ48047346
Dimeric Brucella abortus Irr protein controls its own expression and binds haemQ48118222
Molecular cloning and nucleotide sequencing of oxyR, the positive regulatory gene of a regulon for an adaptive response to oxidative stress in Escherichia coli: homologies between OxyR protein and a family of bacterial activator proteinsQ50194168
Oxidative stress promotes degradation of the Irr protein to regulate haem biosynthesis in Bradyrhizobium japonicum.Q51242218
Thioredoxin 2 is involved in the oxidative stress response in Escherichia coli.Q52537783
The Rhizobium leguminosarum regulator IrrA affects the transcription of a wide range of genes in response to Fe availability.Q54466630
Fur is not the global regulator of iron uptake genes in Rhizobium leguminosarum.Q54526080
The Bradyrhizobium japonicum Fur protein is an iron-responsive regulator in vivo.Q54576277
Proteomic analysis reveals the wide-ranging effects of the novel, iron-responsive regulator RirA in Rhizobium leguminosarum bv. viciae.Q54667779
Transcriptional Regulation of Glutaredoxin and Thioredoxin Pathways and Related Enzymes in Response to Oxidative StressQ60253894
Interaction between the bacterial iron response regulator and ferrochelatase mediates genetic control of heme biosynthesisQ77530167
The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pyloriQ77748405
RirA, an iron-responsive regulator in the symbiotic bacterium Rhizobium leguminosarumQ78655560
Irr regulates brucebactin and 2,3-dihydroxybenzoic acid biosynthesis, and is implicated in the oxidative stress resistance and intracellular survival of Brucella abortusQ80199323
Evidence that the Rhizobium regulatory protein RirA binds to cis-acting iron-responsive operators (IROs) at promoters of some Fe-regulated genesQ81104304
RirA is the iron response regulator of the rhizobactin 1021 biosynthesis and transport genes in Sinorhizobium meliloti 2011Q81756260
P433issue1
P921main subjectProteobacteriaQ130999
P304page(s)89-97
P577publication date2008-12-18
P1433published inBioMetalsQ15767134
P1476titleHeme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other Alpha-proteobacteria
P478volume22

Reverse relations

cites work (P2860)
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