The iron-responsive regulator irr is required for wild-type expression of the gene encoding the heme transporter BhuA in Brucella abortus 2308.

scientific article published on 29 July 2011

The iron-responsive regulator irr is required for wild-type expression of the gene encoding the heme transporter BhuA in Brucella abortus 2308. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.00372-11
P932PMC publication ID3187407
P698PubMed publication ID21804001

P2093author name stringJames T Paulley
Kendra H Steele
R Martin Roop
Eric S Anderson
Jennifer M Gaines
David A Martinson
P2860cites workHepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalizationQ24310115
Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettesQ29615258
The Brucella abortus CcrM DNA methyltransferase is essential for viability, and its overexpression attenuates intracellular replication in murine macrophagesQ33602895
Brucella melitensis: a nasty bug with hidden credentials for virulenceQ33896055
The Iron control element, acting in positive and negative control of iron-regulated Bradyrhizobium japonicum genes, is a target for the Irr protein.Q34303284
Bradyrhizobium japonicum senses iron through the status of haem to regulate iron homeostasis and metabolismQ34507192
Characterization and genetic complementation of a Brucella abortus high-temperature-requirement A (htrA) deletion mutant.Q34539325
Production of the Siderophore 2,3-Dihydroxybenzoic Acid Is Required for Wild-Type Growth of Brucella abortus in the Presence of Erythritol under Low-Iron Conditions In VitroQ34932916
Modification of iron regulation by the inflammatory response.Q36057894
Identification and cloning of a fur regulatory gene in Yersinia pestisQ36125298
Brucella abortus requires the heme transporter BhuA for maintenance of chronic infection in BALB/c miceQ36313890
The AraC-like transcriptional regulator DhbR is required for maximum expression of the 2,3-dihydroxybenzoic acid biosynthesis genes in Brucella abortus 2308 in response to iron deprivationQ36483235
Heme is an effector molecule for iron-dependent degradation of the bacterial iron response regulator (Irr) protein.Q36665454
Nramp1 phagocyte intracellular metal withdrawal defenseQ37006940
Function, regulation, and transcriptional organization of the hemin utilization locus of Bartonella quintanaQ37032998
Positive control of ferric siderophore receptor gene expression by the Irr protein in Bradyrhizobium japonicumQ37110534
Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other Alpha-proteobacteriaQ37137835
Survival of the fittest: how Brucella strains adapt to their intracellular niche in the hostQ37270179
Identification of 2,3-dihydroxybenzoic acid as a Brucella abortus siderophoreQ40152024
Heme-responsive DNA binding by the global iron regulator Irr from Rhizobium leguminosarum.Q40602641
The role of iron in the biology of Brucella suis. I. Growth and virulenceQ40639449
The bacterial irr protein is required for coordination of heme biosynthesis with iron availabilityQ47682305
The Brucella abortus host factor I (HF-I) protein contributes to stress resistance during stationary phase and is a major determinant of virulence in miceQ47910975
Dimeric Brucella abortus Irr protein controls its own expression and binds haemQ48118222
The Rhizobium leguminosarum regulator IrrA affects the transcription of a wide range of genes in response to Fe availability.Q54466630
Nutrition of Brucellae: utilization of iron, magnesium, and manganese for growthQ73803260
Interaction between the bacterial iron response regulator and ferrochelatase mediates genetic control of heme biosynthesisQ77530167
RirA, an iron-responsive regulator in the symbiotic bacterium Rhizobium leguminosarumQ78655560
Irr regulates brucebactin and 2,3-dihydroxybenzoic acid biosynthesis, and is implicated in the oxidative stress resistance and intracellular survival of Brucella abortusQ80199323
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectBrucella abortusQ11353905
P304page(s)5359-5364
P577publication date2011-07-29
P1433published inJournal of BacteriologyQ478419
P1476titleThe iron-responsive regulator irr is required for wild-type expression of the gene encoding the heme transporter BhuA in Brucella abortus 2308.
P478volume193

Reverse relations

cites work (P2860)
Q33718576A bacterial iron exporter for maintenance of iron homeostasis
Q53612828A new cis-encoded sRNA, BsrH, regulating the expression of hemH gene in Brucella abortus 2308.
Q40148606Differential control of Bradyrhizobium japonicum iron stimulon genes through variable affinity of the iron response regulator (Irr) for target gene promoters and selective loss of activator function
Q42190199HmuP is a coactivator of Irr-dependent expression of heme utilization genes in Bradyrhizobium japonicum
Q36294903Iron response regulator protein IrrB in Magnetospirillum gryphiswaldense MSR-1 helps control the iron/oxygen balance, oxidative stress tolerance, and magnetosome formation
Q40063728Iron-dependent reconfiguration of the proteome underlies the intracellular lifestyle of Brucella abortus.
Q37353570Metal acquisition and virulence in Brucella
Q38330116Mur regulates the gene encoding the manganese transporter MntH in Brucella abortus 2308
Q39103477Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.
Q36156332The bhuQ gene encodes a heme oxygenase that contributes to the ability of Brucella abortus 2308 to use heme as an iron source and is regulated by Irr.
Q45091061The ferrous iron transporter FtrABCD is required for the virulence of Brucella abortus 2308 in mice
Q57056831The manganese-dependent pyruvate kinase PykM is required for wild-type glucose utilization by 2308 and its virulence in C57BL/6 mice
Q88910093Transposon Sequencing of Brucella abortus Uncovers Essential Genes for Growth In Vitro and Inside Macrophages

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