Brucella abortus requires the heme transporter BhuA for maintenance of chronic infection in BALB/c mice

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Brucella abortus requires the heme transporter BhuA for maintenance of chronic infection in BALB/c mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00460-07
P932PMC publication ID2168305
P698PubMed publication ID17709407

P2093author name stringJames T Paulley
R Martin Roop
Eric S Anderson
P2860cites workCompletion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suisQ22065444
Nucleotide sequence of the gene for the ferrienterochelin receptor FepA in Escherichia coli. Homology among outer membrane receptors that interact with TonB.Q41791003
Discovery of a haem uptake system in the soil bacterium Bradyrhizobium japonicumQ42658366
Structure of the Shigella dysenteriae haem transport locus and its phylogenetic distribution in enteric bacteriaQ42681729
Brucella abortus siderophore 2,3-dihydroxybenzoic acid (DHBA) facilitates intracellular survival of the bacteriaQ44032829
The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c miceQ47885211
Haem utilization in Vibrio cholerae involves multiple TonB-dependent haem receptorsQ77291477
Whole-Genome Analyses of Speciation Events in Pathogenic BrucellaeQ22065492
The genome sequence of the facultative intracellular pathogen Brucella melitensisQ22066222
The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbiontsQ22066244
A new mathematical model for relative quantification in real-time RT-PCRQ27860781
Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress responseQ28492822
The Ton system, an ABC transporter, and a universally conserved GTPase are involved in iron utilization by Brucella melitensis 16M.Q31114739
Cloning and characterization of an outer membrane protein of Vibrio vulnificus required for heme utilization: regulation of expression and determination of the gene sequenceQ33756125
The Brucella abortus Cu,Zn superoxide dismutase is required for optimal resistance to oxidative killing by murine macrophages and wild-type virulence in experimentally infected miceQ33768886
The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB/c miceQ33867901
Hemin uptake system of Yersinia enterocolitica: similarities with other TonB-dependent systems in gram-negative bacteriaQ33938714
Interruption of the cydB locus in Brucella abortus attenuates intracellular survival and virulence in the mouse model of infectionQ33995977
Molecular characterization of the hemin uptake locus (hmu) from Yersinia pestis and analysis of hmu mutants for hemin and hemoprotein utilization.Q34001362
TonB-dependent systems of uropathogenic Escherichia coli: aerobactin and heme transport and TonB are required for virulence in the mouseQ34009302
Ferrochelatase is present in Brucella abortus and is critical for its intracellular survival and virulenceQ34009336
Characterization of the Plesiomonas shigelloides genes encoding the heme iron utilization systemQ34011300
BhuR, a virulence-associated outer membrane protein of Bordetella avium, is required for the acquisition of iron from heme and hemoproteinsQ34132423
Cellular and molecular mechanisms of senescent erythrocyte phagocytosis by macrophages. A review.Q34468151
Characterization and genetic complementation of a Brucella abortus high-temperature-requirement A (htrA) deletion mutant.Q34539325
Iron and microbial infectionQ34650077
Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells.Q34744746
Genetic organization and iron-responsive regulation of the Brucella abortus 2,3-dihydroxybenzoic acid biosynthesis operon, a cluster of genes required for wild-type virulence in pregnant cattleQ34853905
BrucellaStationary-Phase Gene Expression and VirulenceQ35121003
Complex role of hemoglobin and hemoglobin-haptoglobin binding proteins in Haemophilus influenzae virulence in the infant rat model of invasive infection.Q35217539
Staphylococcus aureus IsdB is a hemoglobin receptor required for heme iron utilization.Q35220663
Identification of shuA, the gene encoding the heme receptor of Shigella dysenteriae, and analysis of invasion and intracellular multiplication of a shuA mutant.Q35561276
Adaptation of the Brucellae to their intracellular nicheQ35752932
Aquisition, mobilization and utilization of cellular iron and heme: endless findings and growing evidence of tight regulationQ36063092
Identification and cloning of a fur regulatory gene in Yersinia pestisQ36125298
A developmentally regulated Caulobacter flagellar promoter is activated by 3' enhancer and IHF binding elementsQ37373713
TonB is required for intracellular growth and virulence of Shigella dysenteriae.Q39516873
Use of heme-protein complexes by the Yersinia enterocolitica HemR receptor: histidine residues are essential for receptor function.Q39547650
Identification of 2,3-dihydroxybenzoic acid as a Brucella abortus siderophoreQ40152024
Brucella abortus strain 2308 produces brucebactin, a highly efficient catecholic siderophore.Q40752306
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectBrucella abortusQ11353905
P304page(s)5248-5254
P577publication date2007-08-20
P1433published inInfection and ImmunityQ6029193
P1476titleBrucella abortus requires the heme transporter BhuA for maintenance of chronic infection in BALB/c mice
P478volume75

Reverse relations

cites work (P2860)
Q53612828A new cis-encoded sRNA, BsrH, regulating the expression of hemH gene in Brucella abortus 2308.
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Q34189311Differential expression of iron acquisition genes by Brucella melitensis and Brucella canis during macrophage infection
Q37148846Expression, purification, crystallization and preliminary X-ray diffraction analysis of the TonB-dependent haem outer membrane transporter ShuA from Shigella dysenteriae
Q60907519Identification of Cross-Protective Potential Antigens against Pathogenic spp. through Combining Pan-Genome Analysis with Reverse Vaccinology
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Q39636373Iron homeostasis in Brucella abortus: the role of bacterioferritin
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Q37353570Metal acquisition and virulence in Brucella
Q38330116Mur regulates the gene encoding the manganese transporter MntH in Brucella abortus 2308
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Q36483235The AraC-like transcriptional regulator DhbR is required for maximum expression of the 2,3-dihydroxybenzoic acid biosynthesis genes in Brucella abortus 2308 in response to iron deprivation
Q36156332The bhuQ gene encodes a heme oxygenase that contributes to the ability of Brucella abortus 2308 to use heme as an iron source and is regulated by Irr.
Q42774011The effects of MucR on expression of type IV secretion system, quorum sensing system and stress responses in Brucella melitensis
Q45091061The ferrous iron transporter FtrABCD is required for the virulence of Brucella abortus 2308 in mice
Q38631036The iron-responsive regulator irr is required for wild-type expression of the gene encoding the heme transporter BhuA in Brucella abortus 2308.
Q37274852The manganese transporter MntH is a critical virulence determinant for Brucella abortus 2308 in experimentally infected mice

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