scholarly article | Q13442814 |
P50 | author | James Costello | Q80183609 |
P2093 | author name string | James J Collins | |
Orian S Shirihai | |||
Marc Liesa | |||
Catherine S Spina | |||
J Ruben Morones-Ramirez | |||
Anthony Molina | |||
Shimyn Slomovic | |||
Sameer Kalghatgi | |||
P2860 | cites work | Mechanism of bactericidal action of aminoglycosides. | Q39675399 |
Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines | Q40211387 | ||
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation | Q40490388 | ||
N-acetyl-l-cysteine. | Q40865217 | ||
Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells. | Q41154998 | ||
Isolation of human cell lines lacking mitochondrial DNA. | Q41244296 | ||
Nephrotoxicity of beta-lactam antibiotics: mechanisms and strategies for prevention | Q41686944 | ||
Contribution of oxidative damage to antimicrobial lethality. | Q41808795 | ||
The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells | Q46113141 | ||
The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex | Q46560335 | ||
Interaction of beta-lactam antibiotics with the mitochondrial carnitine/acylcarnitine transporter | Q46614628 | ||
H2S: a universal defense against antibiotics in bacteria | Q46754342 | ||
The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid | Q69353201 | ||
Killing by bactericidal antibiotics does not depend on reactive oxygen species | Q86312935 | ||
Mitochondrial evolution | Q22065556 | ||
Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones | Q24548260 | ||
New insights into the role of mitochondria in aging: mitochondrial dynamics and more | Q24600600 | ||
The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro | Q24670241 | ||
Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems | Q24679491 | ||
A common mechanism of cellular death induced by bactericidal antibiotics | Q28246128 | ||
Glutathione | Q28261279 | ||
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics | Q28264943 | ||
Mitochondrial formation of reactive oxygen species | Q29547906 | ||
Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity | Q30488706 | ||
Aminoglycosides: nephrotoxicity | Q33605648 | ||
Contribution of reactive oxygen species to pathways of quinolone-mediated bacterial cell death | Q33636218 | ||
Mitochondrial dysfunction in cardiac disease: ischemia--reperfusion, aging, and heart failure | Q33953515 | ||
Fluoroquinolone-associated tendinopathy: a critical review of the literature | Q34199899 | ||
A murine model of urinary tract infection | Q34236010 | ||
Prevalence of mitochondrial DNA disease in adults | Q34691723 | ||
Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli | Q35742369 | ||
Proposed molecular and cellular mechanism for aminoglycoside ototoxicity | Q35822046 | ||
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. | Q36132703 | ||
Inhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents. | Q36364252 | ||
Cell death from antibiotics without the involvement of reactive oxygen species | Q37065875 | ||
Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. | Q37198083 | ||
Aminoglycoside-induced hearing loss in humans | Q38676819 | ||
The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria | Q39279622 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 192 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mitochondrion | Q39572 |
antibiotic | Q12187 | ||
P304 | page(s) | 192ra85 | |
P577 | publication date | 2013-07-01 | |
P1433 | published in | Science Translational Medicine | Q1573955 |
P1476 | title | Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells | |
P478 | volume | 5 |
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