How might novel technologies such as optogenetics lead to better treatments in epilepsy?

scientific article published on January 2014

How might novel technologies such as optogenetics lead to better treatments in epilepsy? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/978-94-017-8914-1_26
P8608Fatcat IDrelease_57ufnye2vzhdlcr2rtcbdd5n7u
P932PMC publication ID4968566
P698PubMed publication ID25012388

P50authorMarco LedriQ59277168
P2093author name stringIvan Soltesz
Merab Kokaia
Esther Krook-Magnuson
P2860cites workThe temporal and spatial origins of cortical interneurons predict their physiological subtype.Q52033581
Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system.Q54268172
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouseQ58340638
Ion channels and epilepsyQ82635248
Optogenetic Dissection of Neuronal Circuits in Zebrafish using Viral Gene Transfer and the Tet SystemQ21129092
Global and local fMRI signals driven by neurons defined optogenetically by type and wiringQ22122183
High-efficiency channelrhodopsins for fast neuronal stimulation at low light levelsQ24598917
High-performance genetically targetable optical neural silencing by light-driven proton pumpsQ24608810
A wirelessly powered and controlled device for optical neural control of freely-behaving animalsQ24621949
Channelrhodopsin-2, a directly light-gated cation-selective membrane channelQ24631167
Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissueQ24631866
A user's guide to channelrhodopsin variants: features, limitations and future developmentsQ24632166
Millisecond-timescale optical control of neural dynamics in the nonhuman primate brainQ24634574
Characterization of engineered channelrhodopsin variants with improved properties and kineticsQ24643440
Optogenetic control of epileptiform activityQ24644895
Neurons born in the adult dentate gyrus form functional synapses with target cellsQ24648754
Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteriQ24649918
A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mappingQ24651191
New dimensions of interneuronal specialization unmasked by principal cell heterogeneityQ26853650
Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy modelQ27323875
Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoterQ27336119
Millisecond-timescale, genetically targeted optical control of neural activityQ27860591
Changes in granule cell firing rates precede locally recorded spontaneous seizures by minutes in an animal model of temporal lobe epilepsyQ47865779
A glass-coated tungsten microelectrode enclosing optical fibers for optogenetic exploration in primate deep brain structures.Q48380081
Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study.Q48478830
Altered profile of basket cell afferent synapses in hyper-excitable dentate gyrus revealed by optogenetic and two-pathway stimulations.Q48562624
Integrated device for combined optical neuromodulation and electrical recording for chronic in vivo applications.Q48788988
Synaptic connections from multiple subfields contribute to granule cell hyperexcitability in hippocampal slice cultures.Q49162375
Molecular and cellular approaches for diversifying and extending optogeneticsQ28277124
The spatial and temporal origin of chandelier cells in mouse neocortexQ28279922
Role of nucleotide sequences of loxP spacer region in Cre-mediated recombinationQ28280406
Optical control of mammalian endogenous transcription and epigenetic statesQ28505596
Structural and molecular interrogation of intact biological systemsQ29616195
Neocortical excitation/inhibition balance in information processing and social dysfunctionQ29616196
Interneurons of the hippocampusQ29618946
Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operationsQ29620030
Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populationsQ30446227
Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortexQ30494716
On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsyQ30533949
Spatially clustered neuronal assemblies comprise the microstructure of synchrony in chronically epileptic networksQ30537137
In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2.Q30539136
Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injuryQ30541144
Closed-loop optogenetic intervention in miceQ30576206
Connectomics and epilepsyQ30588566
Neuroimaging of epilepsyQ31136944
Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP.Q33387744
High precision and fast functional mapping of cortical circuitry through a novel combination of voltage sensitive dye imaging and laser scanning photostimulationQ33529362
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trialQ33905053
Developmental origin dictates interneuron AMPA and NMDA receptor subunit composition and plasticityQ34044120
Optical control of focal epilepsy in vivo with caged γ-aminobutyric acidQ34046135
Ultrafast optogenetic control.Q34093362
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structuresQ34102272
Optetrode: a multichannel readout for optogenetic control in freely moving miceQ34184443
Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsinsQ34196212
Multi-array silicon probes with integrated optical fibers: light-assisted perturbation and recording of local neural circuits in the behaving animalQ34198141
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex.Q34219089
Neurostimulation for the treatment of epilepsy: a review of current surgical interventionsQ34297472
An optogenetic approach in epilepsyQ34304480
Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsyQ34311339
Current status of gene therapy for brain tumors.Q34318157
An integrated μLED optrode for optogenetic stimulation and electrical recording.Q34411558
Cholecystokinin: a multi-functional molecular switch of neuronal circuitsQ34420892
Optical induction of synaptic plasticity using a light-sensitive channel.Q34596094
Circuit-breakers: optical technologies for probing neural signals and systemsQ34654330
Optogenetically induced seizure and the longitudinal hippocampal network dynamicsQ34674356
Targeting and readout strategies for fast optical neural control in vitro and in vivoQ34730559
A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortexQ34853721
Bi-stable neural state switchesQ34903131
Control of synchronization of brain dynamics leads to control of epileptic seizures in rodentsQ35061621
Single-neuron dynamics in human focal epilepsyQ35099268
Target-selective GABAergic control of entorhinal cortex outputQ35114673
Ivy cells: a population of nitric-oxide-producing, slow-spiking GABAergic neurons and their involvement in hippocampal network activityQ35805240
Towards reliable spike-train recordings from thousands of neurons with multielectrodesQ35857663
Spatiotemporal neuronal correlates of seizure generation in focal epilepsyQ35920543
Neurogliaform and Ivy Cells: A Major Family of nNOS Expressing GABAergic NeuronsQ35963176
Somatostatin and neuropeptide Y neurons undergo different plasticity in parahippocampal regions in kainic acid-induced epilepsyQ36103127
Lighting the chandelier: new vistas for axo-axonic cellsQ36146223
Diode probes for spatiotemporal optical control of multiple neurons in freely moving animalsQ36211314
Toward a full-scale computational model of the rat dentate gyrusQ36403984
Standard antiepileptic drugs fail to block epileptiform activity in rat organotypic hippocampal slice culturesQ36736095
A high-resolution enhancer atlas of the developing telencephalonQ36862710
Tools, methods, and applications for optophysiology in neuroscienceQ37019105
The promise of gene therapy for the treatment of epilepsyQ37021317
Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patientsQ37027502
Injectable, cellular-scale optoelectronics with applications for wireless optogenetics.Q37162596
Quantitative assessment of CA1 local circuits: knowledge base for interneuron-pyramidal cell connectivity.Q37179260
Informational lesions: optical perturbation of spike timing and neural synchrony via microbial opsin gene fusionsQ37343569
The therapeutic potential of focal cooling for neocortical epilepsyQ37426955
Developmental mechanisms for the generation of telencephalic interneurons.Q37864259
Basket cell dichotomy in microcircuit functionQ37971369
Complex single gene disorders and epilepsy.Q38040446
Optogenetics in epilepsyQ38110869
A neural circuit for spatial summation in visual cortexQ39709858
Multiwaveguide implantable probe for light delivery to sets of distributed brain targetsQ41480429
A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencingQ42137770
A 3D glass optrode array for optical neural stimulationQ42270039
Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmissionQ42321485
Organization of the GABAergic system in the rat hippocampal formation: a quantitative immunocytochemical studyQ42505474
Closed-loop control of epilepsy by transcranial electrical stimulation.Q42710892
Anticonvulsant and antiepileptogenic effects mediated by adeno-associated virus vector neuropeptide Y expression in the rat hippocampus.Q44814719
Efficient unsupervised algorithms for the detection of seizures in continuous EEG recordings from rats after brain injuryQ46841981
P407language of work or nameEnglishQ1860
P921main subjectoptogeneticsQ781492
leadQ708
P304page(s)319-336
P577publication date2014-01-01
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titleHow might novel technologies such as optogenetics lead to better treatments in epilepsy?
P478volume813

Reverse relations

cites work (P2860)
Q34464281Beyond the hammer and the scalpel: selective circuit control for the epilepsies
Q34948808Cerebellar Directed Optogenetic Intervention Inhibits Spontaneous Hippocampal Seizures in a Mouse Model of Temporal Lobe Epilepsy
Q42405385DREADDnoughts Join in the Battle for Seizure Control
Q26827783Future of seizure prediction and intervention: closing the loop
Q47734973Hippocampal GABAergic Inhibitory Interneurons
Q41266313In vivo evaluation of the dentate gate theory in epilepsy.
Q28087559Neuroelectronics and Biooptics: Closed-Loop Technologies in Neurological Disorders
Q35220504Resolution revolution: epilepsy dynamics at the microscale
Q55440525Specificity, Versatility, and Continual Development: The Power of Optogenetics for Epilepsy Research.
Q61449132The Role of BDNF in Peripheral Nerve Regeneration: Activity-Dependent Treatments and Val66Met
Q33779967Zebrafish as an animal model in epilepsy studies with multichannel EEG recordings

Search more.