14-3-3s are potential biomarkers for HIV-related neurodegeneration

scientific article published on 19 July 2012

14-3-3s are potential biomarkers for HIV-related neurodegeneration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S13365-012-0121-2
P932PMC publication ID3763985
P698PubMed publication ID22811265

P2093author name stringSummer F Acevedo
Diana Morales
Efthimios C M Skoulakis
P2860cites workHepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1Q22011109
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Hepatitis C virus differentially modulates activation of forkhead transcription factors and insulin-induced metabolic gene expressionQ24606745
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infectionQ24608690
Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and functionQ24648178
Human immunodeficiency virus vpr product is a virion-associated regulatory proteinQ24649600
Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infectionQ24652969
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activityQ24685633
Human CNS cultures exposed to HIV-1 gp120 reproduce dendritic injuries of HIV-1-associated dementiaQ24794489
Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand bindingQ27619633
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14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndromeQ28178021
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HIV-1 accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of forkhead transcription factors by interfering with their binding to 14-3-3 proteins: potential clinical implications regarding the insulin resistance of HIV-1-infectQ45199116
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Human 14-3-3 protein: radioimmunoassay, tissue distribution, and cerebrospinal fluid levels in patients with neurological disordersQ48949632
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Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.Q52209534
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.Q53231720
HCV core protein promotes heparin binding EGF-like growth factor expression and activates Akt.Q53260500
The diagnostic efficiency of biomarkers in sporadic Creutzfeldt-Jakob disease compared to Alzheimer's disease.Q53292933
Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease.Q53888877
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Cerebrospinal fluid biomarkers in clinically isolated syndromes and multiple sclerosisQ59505826
Diagnostic value of CSF 14-3-3 detection in sporadic CJD diagnosis according to the age of the patientQ62381832
Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120Q67572030
Exposure to gp120 of HIV‐1 Induces an Increased Release of Arachidonic Acid in Rat Primary Neuronal Cell Culture Followed by NMDA Receptor‐mediated NeurotoxicityQ71795847
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodiesQ72815795
Diagnosis of Creutzfeldt-Jakob disease: effect of clinical criteria on incidence estimatesQ73556100
14-3-3 protein in the cerebrospinal fluid of patients with acute transverse myelitisQ73639546
Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt-Jakob diseaseQ74333080
Gatekeeper role of 14-3-3tau protein in HIV-1 gp120-mediated apoptosis of human endothelial cells by inactivation of BadQ80211870
HIV-1 Vpr induces G2 cell cycle arrest in fission yeast associated with Rad24/14-3-3-dependent, Chk1/Cds1-independent Wee1 upregulationQ80250592
Genetic isolation of transport signals directing cell surface expressionQ81197748
Association of 14-3-3 epsilon gene haplotype with completed suicide in JapaneseQ81663512
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HIV/hepatitis C coinfection natural history and disease progressionQ35801431
Pharmacological chaperones: potential treatment for conformational diseases.Q35820522
K2P channels and their protein partners.Q36142862
14-3-3 proteins: regulators of numerous eukaryotic proteinsQ36276386
Regulation of neural cell survival by HIV-1 infection.Q36317663
14-3-3 proteins: a historic overviewQ36470005
14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 VprQ36665575
Host factors exploited by retrovirusesQ36746350
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Enhancement of the surface expression of G protein-coupled receptors.Q37316198
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Trafficking of neuronal two pore domain potassium channelsQ37848077
Structural basis of 14-3-3 protein functions.Q37932715
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Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrestQ39880367
HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration.Q40149510
Interaction of HCV core protein with 14-3-3epsilon protein releases Bax to activate apoptosisQ40201962
Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.Q40717934
14-3-3 proteins: biological function and domain structureQ40949003
HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivoQ41071784
Phosphorylation-dependent C-terminal binding of 14-3-3 proteins promotes cell surface expression of HIV co-receptor GPR15.Q41955759
14-3-3 protein in CSF: an early predictor of SIV CNS diseaseQ42476359
Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV.Q43038781
Detection of 14-3-3 brain protein in cerebrospinal fluid of HIV infected patientsQ43062342
Increased concentrations of 14-3-3 epsilon, gamma and zeta isoforms in cerebrospinal fluid of AIDS patients with neuronal destructionQ43753321
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brainQ43850058
Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob diseaseQ43863115
Increased LIS1 expression affects human and mouse brain developmentQ30639738
Clinical diagnosis and differential diagnosis of CJD and vCJD. With special emphasis on laboratory testsQ30698122
14-3-3 proteins in the nervous systemQ33188355
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligaseQ33290831
Binding of 14-3-3beta to the carboxyl terminus of Wee1 increases Wee1 stability, kinase activity, and G2-M cell populationQ33292199
Synaptic proteins linked to HIV-1 infection and immunoproteasome induction: proteomic analysis of human synaptosomesQ33495226
Neuronal number and volume alterations in the neocortex of HIV infected individuals.Q33591126
Pathogenesis of HIV in the central nervous systemQ33781978
Patterns of CCR5, CXCR4, and CCR3 usage by envelope glycoproteins from human immunodeficiency virus type 1 primary isolates.Q33782930
Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activationQ33801078
Vpr protein of human immunodeficiency virus type 1 binds to 14-3-3 proteins and facilitates complex formation with Cdc25C: implications for cell cycle arrestQ33834244
Treatable neurological disorders misdiagnosed as Creutzfeldt-Jakob diseaseQ33933305
Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.Q33997189
Neurocognitive impairment and HIV risk factors: a reciprocal relationshipQ34005620
How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesisQ34120299
14-3-3 proteins: regulation of subcellular localization by molecular interferenceQ34127838
Identification of a protein encoded by the vpu gene of HIV-1.Q34163678
Identification of HIV-1 vpr product and functionQ34168026
Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.Q34341976
Specificity of 14-3-3 isoform dimer interactions and phosphorylationQ34797095
Specific 14-3-3 isoform detection and immunolocalization in prion diseasesQ34797160
HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic interventionQ34957142
Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive declineQ34988032
PI3K/Akt signalling-mediated protein surface expression sensed by 14-3-3 interacting motifQ34993298
The dynamics of cell cycle regulation.Q35007334
Human immunodeficiency virus-associated dementia: an evolving diseaseQ35112016
Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.Q35114694
The 14-3-3 proteins: gene, gene expression, and functionQ35166332
Miller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouseQ35194904
Models of neuronal injury in AIDS: another role for the NMDA receptor?Q35315325
Patients with Alzheimer's disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob diseaseQ35462665
The role of specific isoforms of 14-3-3 protein in regulating protein kinase activity in the brainQ35491257
14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteinsQ35624026
P433issue5
P921main subjectbiomarkerQ864574
neurodegenerationQ1755122
P304page(s)341-353
P577publication date2012-07-19
P1433published inJournal of NeuroVirologyQ6295640
P1476title14-3-3s are potential biomarkers for HIV-related neurodegeneration
P478volume18

Reverse relations

cites work (P2860)
Q9202607514-3-3 Proteins Are on the Crossroads of Cancer, Aging, and Age-Related Neurodegenerative Disease
Q6409345314-3-3ε acts as a proviral factor in highly pathogenic porcine reproductive and respiratory syndrome virus infection
Q4714191314-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells
Q35236882Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders
Q38173380Neuroprotective function of 14-3-3 proteins in neurodegeneration
Q37657002YWHAE/14-3-3ε: a potential novel genetic risk factor and CSF biomarker for HIV neurocognitive impairment