Motexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a Children's Oncology Group phase I study

scientific article published on 20 August 2008

Motexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a Children's Oncology Group phase I study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1215/15228517-2008-043
P932PMC publication ID2666252
P698PubMed publication ID18715950
P5875ResearchGate publication ID23183159

P50authorMinesh MehtaQ56533682
Susan M BlaneyQ73565675
P2093author name stringChildren's Oncology Group
Percy Ivy
Peter C Adamson
Ian F Pollack
Joel M Reid
Mark Krailo
Matthew M Ames
Gregory Reaman
Tianni Zhou
Gilbert Vezina
Kristin A Bradley
P2860cites workPhase 1 study of concurrent RMP-7 and carboplatin with radiotherapy for children with newly diagnosed brainstem gliomas.Q55471181
Corticosteroid-induced magnetic resonance imaging changes in patients with recurrent malignant glioma.Q55481768
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A phase I study of topotecan as a radiosensitizer for brainstem glioma of childhood: first report of the Children's Cancer Group-0952Q24671734
Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductaseQ28567883
A clinicopathologic reappraisal of brain stem tumor classification. Identification of pilocystic astrocytoma and fibrillary astrocytoma as distinct entitiesQ30615083
Multicenter phase Ib/II trial of the radiation enhancer motexafin gadolinium in patients with brain metastasesQ30662282
Lead-in phase to randomized trial of motexafin gadolinium and whole-brain radiation for patients with brain metastases: centralized assessment of magnetic resonance imaging, neurocognitive, and neurologic end pointsQ30713105
Diffuse brainstem glioma in children: critical review of clinical trialsQ31033307
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Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastasesQ35164078
Neurocognitive function and progression in patients with brain metastases treated with whole-brain radiation and motexafin gadolinium: results of a randomized phase III trialQ35618873
Final results of a study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: a Pediatric Oncology Group studyQ36773672
UKCCSG study of accelerated radiotherapy for pediatric brain stem gliomas. United Kingdom Childhood Cancer Study GroupQ36879740
Phase I and pharmacokinetic study of the novel redox-active agent, motexafin gadolinium, with concurrent radiation therapy in patients with locally advanced pancreatic or biliary cancersQ40499821
Prognostic factors in pediatric brain-stem gliomasQ41344144
Population pharmacokinetics of motexafin gadolinium in adults with brain metastases or glioblastoma multiformeQ42647577
A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brainstem gliomaQ44374100
Topotecan as a radiosensitizer in the treatment of children with malignant diffuse brainstem gliomas: results of a French Society of Paediatric Oncology Phase II StudyQ44483736
The treatment of brain stem and thalamic gliomas with 78 Gy of hyperfractionated radiation therapyQ46221713
Hyperfractionated radiation therapy (72 Gy) for children with brain stem gliomas. A Childrens Cancer Group Phase I/II TrialQ48232854
Hyperfractionated radiotherapy in the management of diffuse intrinsic brainstem tumors: when is enough enough?Q48245743
Trends in reported incidence of primary malignant brain tumors in children in the United StatesQ48398308
Carboplatin before and during radiation therapy for the treatment of malignant brain stem tumours: a study by the Société Française d'Oncologie PédiatriqueQ48637093
Hyperfractionated radiotherapy for children with brainstem gliomas: a pilot study using 7,200 cGy.Q49111287
Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy. A Childrens Cancer Group Phase I/II Trial.Q54194990
P433issue5
P921main subjectgadoliniumQ1832
adaptive radiation therapyQ180507
P304page(s)752-758
P577publication date2008-08-20
P1433published inNeuro-OncologyQ15724471
P1476titleMotexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a Children's Oncology Group phase I study
P478volume10

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