Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery.

scientific article

Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery. is …
instance of (P31):
scholarly articleQ13442814

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P5530Altmetric DOI10.1016/J.JCONREL.2018.05.005
P6179Dimensions Publication ID1103972056
P356DOI10.1016/J.JCONREL.2018.05.005
P953full work available at URLhttp://eprints.whiterose.ac.uk/132017/
P932PMC publication ID6026028
P698PubMed publication ID29753957
P1154Scopus EID2-s2.0-85047251823

P50authorDaniel ColucciaQ56450174
Heiko WurdakQ89782444
Kullervo HynynenQ31088142
P2093author name stringJames T Rutka
Brian Golbourn
Christian Smith
Nesrin Sabha
Meaghan O'Reilly
Amanda Luck
Saira Alli
Andrew Bondoc
Carlyn A Figueiredo
Colin Maslink
Megan Yijun Wu
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Chronic, intermittent convection-enhanced delivery devicesQ26776237
DIPG in Children - What Can We Learn from the Past?Q26777843
Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical studyQ27334453
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In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine gliomaQ28487205
Functionally defined therapeutic targets in diffuse intrinsic pontine gliomaQ28833173
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastomaQ29616862
Characterization of Different Microbubbles in Assisting Focused Ultrasound-Induced Blood-Brain Barrier Opening.Q30358276
Opening the Blood-Brain Barrier with MR Imaging-guided Focused Ultrasound: Preclinical Testing on a Trans-Human Skull Porcine Model.Q30367034
Intracranial applications of magnetic resonance-guided focused ultrasound.Q30384529
Focused ultrasound-mediated drug delivery through the blood-brain barrierQ30394357
Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: potential for targeting experimental brain tumorsQ30407973
Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncologyQ30434475
Diffuse intrinsic pontine gliomas-current management and new biologic insights. Is there a glimmer of hope?Q47580461
Blood-Brain Barrier Closure Time After Controlled Ultrasound-Induced Opening Is Independent of Opening VolumeQ48346915
An epigenetic therapy for diffuse intrinsic pontine gliomas.Q48424265
Intracerebral chemotherapy: chronic microinfusion of cisplatinQ48968255
Mechanism of Low-Frequency Ultrasound in Opening Blood–Tumor Barrier by Tight JunctionQ50441989
Short and long-term motor skill learning in an accelerated rotarod training paradigm.Q52090583
In vivo and in vitro evidence for ATP-dependency of P-glycoprotein-mediated efflux of doxorubicin at the blood-brain barrier.Q54172518
Relationship between specific gravity, water content, and serum protein extravasation in various types of vasogenic brain edema.Q55488962
Comparative pharmacokinetics of free doxorubicin and doxorubicin entrapped in cardiolipin liposomesQ69485193
Focused ultrasound delivers targeted immune cells to metastatic brain tumorsQ30441716
Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat gliomaQ30448863
Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaquesQ30452238
Blood-brain barrier: real-time feedback-controlled focused ultrasound disruption by using an acoustic emissions-based controllerQ30455962
Ultrasound insertion loss of rat parietal bone appears to be proportional to animal mass at submegahertz frequenciesQ30462013
A PVDF receiver for ultrasound monitoring of transcranial focused ultrasound therapyQ30472865
Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo.Q30474719
Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endotheliumQ30488665
Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruptionQ30500905
Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implicationsQ30837732
Advances toward an understanding of brainstem gliomasQ31033870
Improved HPLC method for doxorubicin quantification in rat plasma to study the pharmacokinetics of micelle-encapsulated and liposome-encapsulated doxorubicin formulationsQ33354476
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade gliomaQ33751426
Chemotherapy for brain stem gliomasQ33768045
New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy.Q33895267
Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbitsQ33954300
Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy.Q33958482
A non-invasive method for focusing ultrasound through the human skullQ33959339
Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrierQ33999429
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytomaQ34810691
Motexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a Children's Oncology Group phase I studyQ37152041
Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation.Q37577170
Diffuse intrinsic pontine gliomas: treatments and controversiesQ38216988
Modeling localized delivery of Doxorubicin to the brain following focused ultrasound enhanced blood-brain barrier permeabilityQ39127658
Evaluation of permeability, doxorubicin delivery, and drug retention in a rat brain tumor model after ultrasound-induced blood-tumor barrier disruptionQ39290193
Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble DoseQ43693994
Convection-enhanced delivery of topotecan into diffuse intrinsic brainstem tumors in childrenQ44156403
MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbitsQ46802417
P4510describes a project that usesfocused ultrasoundQ50333304
P407language of work or nameEnglishQ1860
P921main subjectdoxorubicinQ18936
blood–brain barrierQ221694
P304page(s)29-41
P577publication date2018-05-16
P1433published inJournal of Controlled ReleaseQ6295046
P1476titleBrainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery.
P478volume281

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cites work (P2860)
Q101237517Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Q90317315First-in-human trial of blood-brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound
Q89967058Invaders Exposed: Understanding and Targeting Tumor Cell Invasion in Diffuse Intrinsic Pontine Glioma
Q57167169Low-Intensity MR-Guided Focused Ultrasound Mediated Disruption of the Blood-Brain Barrier for Intracranial Metastatic Diseases
Q55251609Malignant Brain Tumours in Children : Present and Future Perspectives.
Q94602503Overcoming the blood brain barrier to target diffuse intrinsic pontine glioma: What's new?
Q64244053Treatment Strategies in Diffuse Midline Gliomas With the H3K27M Mutation: The Role of Convection-Enhanced Delivery in Overcoming Anatomic Challenges

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