| Q51446102 | A Long-lived Mouse Lacking Both Growth Hormone and Growth Hormone Receptor: A New Animal Model for Aging Studies. |
| Q47716658 | A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation |
| Q34424938 | A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner? |
| Q36112487 | Age- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice |
| Q37383914 | Age-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice |
| Q37851872 | Aging and cancer: can mTOR inhibitors kill two birds with one drug? |
| Q40296763 | Aging metabolism: intervention strategies |
| Q48254240 | Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations |
| Q33693451 | Calorie restriction and cancer prevention: metabolic and molecular mechanisms |
| Q34170610 | Calorie restriction and prevention of age-associated chronic disease. |
| Q41628772 | Can FSH influence longevity? |
| Q38618091 | Cause-of-Death Analysis in Rodent Aging Studies |
| Q35971938 | Comparative endocrinology of aging and longevity regulation |
| Q58119900 | Continuous overexpression of thioredoxin 1 enhances cancer development and does not extend maximum lifespan in male C57BL/6 mice |
| Q36990255 | Decreased expression level of apoptosis-related genes and/or proteins in skeletal muscles, but not in hearts, of growth hormone receptor knockout mice |
| Q36253119 | Decreased insulin sensitivity and increased oxidative damage in wasting adipose tissue depots of wild-type mice |
| Q37003167 | Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice. |
| Q36297254 | Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation |
| Q35853682 | Deletion of growth hormone receptor gene but not visceral fat removal decreases expression of apoptosis-related genes in the kidney-potential mechanism of lifespan extension |
| Q36968560 | Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice |
| Q37726297 | Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions |
| Q44965473 | Does eating less make you live longer and better? An update on calorie restriction |
| Q27314852 | Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? |
| Q34422493 | Dynamic analysis of GH receptor conformational changes by split luciferase complementation |
| Q48147612 | Effects of rapamycin on growth hormone receptor knockout mice. |
| Q24613998 | Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse |
| Q37619460 | Evaluation of growth hormone (GH) action in mice: discovery of GH receptor antagonists and clinical indications |
| Q35211637 | Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. |
| Q24599191 | Extending healthy life span--from yeast to humans |
| Q34450441 | Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice |
| Q93164515 | From White to Brown - Adipose Tissue Is Critical to the Extended Lifespan and Healthspan of Growth Hormone Mutant Mice |
| Q38782067 | From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span |
| Q39287747 | GH and ageing: Pitfalls and new insights |
| Q26796574 | Genome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and Worms |
| Q28681454 | Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii |
| Q41573026 | Growth Hormone's Effect on Adipose Tissue: Quality versus Quantity. |
| Q34614325 | Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice. |
| Q46794728 | Growth hormone actions during development influence adult phenotype and longevity |
| Q36410031 | Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice |
| Q24618226 | Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans |
| Q34572500 | Growth hormone signaling is necessary for lifespan extension by dietary methionine |
| Q36159113 | Growth hormone, inflammation and aging |
| Q28390350 | Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice |
| Q38747946 | Healthspan and longevity can be extended by suppression of growth hormone signaling |
| Q26849737 | Healthy aging: is smaller better? - a mini-review |
| Q60053075 | Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity |
| Q37102355 | Higher number of stem cells in the bone marrow of circulating low Igf-1 level Laron dwarf mice--novel view on Igf-1, stem cells and aging. |
| Q22251048 | How ageing processes influence cancer |
| Q37374857 | Human metastatic melanoma cell lines express high levels of growth hormone receptor and respond to GH treatment |
| Q54405530 | IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan. |
| Q39390983 | Impact of Growth Hormone on Regulation of Adipose Tissue. |
| Q33854215 | Impact papers on aging in 2009. |
| Q39094521 | Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species |
| Q35935123 | Interventions to Slow Aging in Humans: Are We Ready? |
| Q36928810 | Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice |
| Q55318581 | Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. |
| Q37503535 | Lifespan extension in genetically modified mice |
| Q27691307 | Links between growth hormone and aging. |
| Q37709205 | Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles |
| Q33849416 | Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-A. |
| Q34402689 | Mammalian models of extended healthy lifespan |
| Q52603773 | Mechanisms of cancer resistance in long-lived mammals. |
| Q39318607 | Metabolic Alterations at the Crossroad of Aging and Oncogenesis |
| Q35670344 | Metabolic effects of intra-abdominal fat in GHRKO mice |
| Q37670847 | Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span |
| Q46309715 | Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species |
| Q37130681 | Mouse models of growth hormone action and aging: a proteomic perspective |
| Q36941459 | Murine models of atrophy, cachexia, and sarcopenia in skeletal muscle |
| Q38260335 | Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency |
| Q37005075 | Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging. |
| Q27008956 | Pathobiology of aging mice and GEM: background strains and experimental design |
| Q33848749 | Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age. |
| Q30575876 | Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model. |
| Q28085421 | Questioning the preclinical paradigm: natural, extreme biology as an alternative discovery platform |
| Q61803760 | ROLE of IGF-1 System in the Modulation of Longevity: Controversies and New Insights From a Centenarians' Perspective |
| Q37000451 | Rapamycin Increases Mortality in db/db Mice, a Mouse Model of Type 2 Diabetes |
| Q36739314 | Rapamycin extends life span of Rb1+/- mice by inhibiting neuroendocrine tumors |
| Q37228766 | Rapamycin extends life- and health span because it slows aging |
| Q33816255 | Rapamycin extends maximal lifespan in cancer-prone mice |
| Q37102346 | Reduced number of VSELs in the bone marrow of growth hormone transgenic mice indicates that chronically elevated Igf1 level accelerates age-dependent exhaustion of pluripotent stem cell pool: a novel view on aging |
| Q35975972 | Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice |
| Q36990243 | Renal pro-apoptotic proteins are reduced by growth hormone resistance but not by visceral fat removal. |
| Q37146692 | Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. |
| Q60919351 | Silencing growth hormone receptor inhibits estrogen receptor negative breast cancer through ATP-binding cassette sub-family G member 2 |
| Q24629563 | Single-gene mutations and healthy ageing in mammals |
| Q41907365 | Somatic growth, aging, and longevity |
| Q37158512 | Somatotropic signaling: trade-offs between growth, reproductive development, and longevity |
| Q37532672 | Some highlights of research on aging with invertebrates, 2009. |
| Q92265740 | Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans' Lifespan |
| Q28077481 | Systemic DNA damage responses in aging and diseases |
| Q33817029 | The GH/IGF-1 axis in ageing and longevity |
| Q37360718 | The effect of calorie restriction on the presence of apoptotic ovarian cells in normal wild type mice and low-plasma-IGF-1 Laron dwarf mice |
| Q37705705 | The effect of low and high plasma levels of insulin-like growth factor-1 (IGF-1) on the morphology of major organs: studies of Laron dwarf and bovine growth hormone transgenic (bGHTg) mice. |
| Q28289018 | The growth hormone receptor: mechanism of activation and clinical implications |
| Q33857579 | The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies. |
| Q33893799 | The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer |
| Q36670184 | The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs). |
| Q36660574 | The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice |
| Q37471096 | The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty |
| Q98613072 | The three dimensions of somatic evolution: Integrating the role of genetic damage, life-history traits, and aging in carcinogenesis |
| Q56418741 | Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice |
| Q38365609 | Tipping the metabolic scales towards increased longevity in mammals |
| Q33552135 | Two-year body composition analyses of long-lived GHR null mice |
| Q93216893 | Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein |
| Q26745908 | Unraveling the message: insights into comparative genomics of the naked mole-rat |
| Q36974726 | Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice. |