CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation

scientific article published on 23 February 2009

CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01737-08
P932PMC publication ID2668377
P698PubMed publication ID19237536

P2093author name stringHua Zhang
Ping Xie
Yuan Zhang
Dongfeng Gu
Cam Patterson
Huihua Li
Mingpeng She
Yongna Fan
P2860cites workCooperation of molecular chaperones with the ubiquitin/proteasome systemQ35967558
Phosphorylated tau and the neurodegenerative foldopathiesQ35992172
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteinsQ36088932
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complexQ40177208
Glycogen synthase kinase 3beta inhibits myocardin-dependent transcription and hypertrophy induction through site-specific phosphorylationQ40377590
The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradationQ40418287
SUMO-1 modification activated GATA4-dependent cardiogenic gene activityQ40520891
Pharmacology of the mouse-isolated cerebral arteryQ45068681
Chaperone-dependent stabilization and degradation of p53 mutantsQ46788559
Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.Q54596085
The RhoA/Rho kinase pathway regulates nuclear localization of serum response factorQ73035716
Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotypeQ73832899
Nonlinearity in intracochlear pressureQ79302481
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functionsQ22010047
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteinsQ24290709
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotypeQ24292785
Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardinQ24311484
The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorQ24562651
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitroQ24608829
Akt and CHIP coregulate tau degradation through coordinated interactionsQ24656202
Myocardin is a master regulator of smooth muscle gene expressionQ24680761
SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4Q28142245
CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell SurvivalQ28183470
ErbB2 degradation mediated by the co-chaperone protein CHIPQ28208008
CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylationQ28216253
Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradationQ28252956
Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in miceQ28506846
PIAS1 activates the expression of smooth muscle cell differentiation marker genes by interacting with serum response factor and class I basic helix-loop-helix proteins.Q28569320
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factorQ28587239
Molecular regulation of vascular smooth muscle cell differentiation in development and diseaseQ29615194
Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerizationQ30306237
Myocardin and Prx1 contribute to angiotensin II-induced expression of smooth muscle alpha-actinQ30312218
5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivoQ30435837
Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cellsQ30441514
C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosisQ33899695
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.Q34304925
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteinsQ35629026
Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblastsQ35642137
Control of smooth muscle development by the myocardin family of transcriptional coactivatorsQ35893541
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
P304page(s)2398-2408
P577publication date2009-02-23
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleCHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation
P478volume29

Reverse relations

cites work (P2860)
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Q37339007C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.
Q35561105Carboxyl terminus of HSC70-interacting protein (CHIP) down-regulates NF-κB-inducing kinase (NIK) and suppresses NIK-induced liver injury
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Q33888579Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts
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Q33554513On to the road to degradation: atherosclerosis and the proteasome
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