Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs

scientific article published on 25 February 2009

Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M809373200
P932PMC publication ID2670124
P698PubMed publication ID19244236

P2093author name stringFranca Cambi
Erming Wang
P2860cites workConserved signals around the 5' splice sites in eukaryotic nuclear precursor mRNAs: G-runs are frequent in the introns and C in the exons near both 5' and 3' splice sitesQ47642838
Conserved quartets near 5' intron junctions in primate nuclear pre-mRNA.Q47643913
Molecular evolution of myelin proteolipid proteinQ47781156
A PLP splicing abnormality is associated with an unusual presentation of PMD.Q48480596
Deletion of a splicing enhancer disrupts PLP1/DM20 ratio and myelin stabilityQ48893147
Members of the heterogeneous nuclear ribonucleoprotein H family activate splicing of an HIV-1 splicing substrate by promoting formation of ATP-dependent spliceosomal complexesQ79873055
Heterogeneous nuclear ribonucleoprotein H is required for optimal U11 small nuclear ribonucleoprotein binding to a retroviral RNA-processing control element: implications for U12-dependent RNA splicingQ81531543
Heterogeneous nuclear ribonucleoprotein F/H proteins modulate the alternative splicing of the apoptotic mediator Bcl-xQ81662355
The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factorQ22008524
The hnRNPs F and H2 bind to similar sequences to influence gene expressionQ24541421
hnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cellsQ24548365
hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cellsQ24554786
The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localizationQ24612895
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-xQ24683323
A combinatorial code for splicing silencing: UAGG and GGGG motifsQ24792190
Mechanisms of alternative pre-messenger RNA splicingQ28131822
PSF and p54(nrb)/NonO--multi-functional nuclear proteinsQ28213410
PLP1 alternative splicing in differentiating oligodendrocytes: characterization of an exonic splicing enhancerQ28576074
Understanding alternative splicing: towards a cellular codeQ29615085
ESEfinder: A web resource to identify exonic splicing enhancersQ29616126
hnRNP complexes: composition, structure, and functionQ29619428
Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicingQ29620837
An increased specificity score matrix for the prediction of SF2/ASF-specific exonic splicing enhancersQ33249150
Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H'/F/2H9 familyQ34092482
Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelinQ34337961
Combinatorial control of exon recognition.Q34585102
An intronic (A/U)GGG repeat enhances the splicing of an alternative intron of the chicken beta-tropomyosin pre-mRNAQ34769833
Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin geneQ35190588
G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selectionQ36570227
Nucleolin: a multiFACeTed protein.Q36678131
Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA SplicingQ37132263
A 5' splice site-proximal enhancer binds SF1 and activates exon bridging of a microexonQ38312386
GRSDB2 and GRS_UTRdb: databases of quadruplex forming G-rich sequences in pre-mRNAs and mRNAsQ38514932
Activation of alpha-tropomyosin exon 2 is regulated by the SR protein 9G8 and heterogeneous nuclear ribonucleoproteins H and F.Q39127727
An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5' splice sitesQ39540203
Cellular and molecular aspects of myelin protein gene expressionQ39581704
SR proteins and hnRNP H regulate the splicing of the HIV-1 tev-specific exon 6D.Q39646678
hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIcQ39969006
Complex splicing control of the human Thrombopoietin gene by intronic G runsQ40198625
Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramideQ40597437
QGRS Mapper: a web-based server for predicting G-quadruplexes in nucleotide sequencesQ42009767
An intron splicing enhancer containing a G-rich repeat facilitates inclusion of a vertebrate micro-exon.Q42022825
PLP/DM20 ratio is regulated by hnRNPH and F and a novel G-rich enhancer in oligodendrocytesQ42547610
Developmental Expression of Proteolipid Protein and DM20 mRNAs and Proteins in the Rat BrainQ43735105
Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or lossQ46234594
The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing eventQ46698520
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectribonucleoprotein complexQ417662
P304page(s)11194-11204
P577publication date2009-02-25
P1433published inJournal of Biological ChemistryQ867727
P1476titleHeterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs
P478volume284

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cites work (P2860)
Q33826558A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.
Q34037595A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions
Q47134651A mechanism underlying position-specific regulation of alternative splicing.
Q34762634Alternative splicing in multiple sclerosis and other autoimmune diseases
Q28480993Binding of hnRNP H and U2AF65 to respective G-codes and a poly-uridine tract collaborate in the N50-5'ss selection of the REST N exon in H69 cells
Q33554183Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms
Q34637786Dual role of G-runs and hnRNP F in the regulation of a mutation-activated pseudoexon in the fibrinogen gamma-chain transcript
Q34575659G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site.
Q34531757Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F
Q40648347Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis
Q53689786Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells.
Q35179872Mechanism of alternative splicing and its regulation
Q39364524MicroRNA expression in mouse oligodendrocytes and regulation of proteolipid protein gene expression
Q55560238Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS.
Q64105728Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing
Q34211868PMD patient mutations reveal a long-distance intronic interaction that regulates PLP1/DM20 alternative splicing
Q38076663Pick one, but be quick: 5' splice sites and the problems of too many choices
Q50978555Proteomics reveals selective regulation of proteins in response to memory-related serotonin stimulation in Aplysia californica ganglia.
Q39760103Regulation of alternative splicing of the receptor for advanced glycation endproducts (RAGE) through G-rich cis-elements and heterogenous nuclear ribonucleoprotein H.
Q47384193Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X.
Q64967604Splicing Factors Have an Essential Role in Prostate Cancer Progression and Androgen Receptor Signaling.
Q38967517Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas
Q38442322The human oligodendrocyte proteome
Q38290499The prevalent deep intronic c. 639+919 G>A GLA mutation causes pseudoexon activation and Fabry disease by abolishing the binding of hnRNPA1 and hnRNP A2/B1 to a splicing silencer.

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